Patents by Inventor A. Evren Ozarslan

A. Evren Ozarslan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Magnetic resonance method, software product, and system for determining a diffusion propagator or related diffusion parameters for spin-labelled particles
    Patent number: 11789106
    Abstract: The present disclosure relates to a computer implemented diffusion magnetic resonance method for determining a diffusion parameter for spin-labelled particles in a specimen.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: October 17, 2023
    Assignee: KALMIA AB
    Inventor: Evren Özarslan
  • A MAGNETIC RESONANCE METHOD, SOFTWARE PRODUCT, AND SYSTEM FOR DETERMINING A DIFFUSION PROPAGATOR OR RELATED DIFFUSION PARAMETERS FOR SPIN-LABELLED PATRICLES
    Publication number: 20230124954
    Abstract: The present disclosure relates to a computer implemented diffusion magnetic resonance method for determining a diffusion parameter for spin-labelled particles in a specimen.
    Type: Application
    Filed: March 26, 2021
    Publication date: April 20, 2023
    Inventor: Evren ÖZARSLAN
  • Magnetic resonance specimen evaluation using multiple pulsed field gradient sequences with a wavenumber magnitude local minimum and restricted compartment estimation
    Patent number: 8704515
    Abstract: Using pulsed-field-gradient (PFG) sequences, the sizes of the pores in ordered porous media can be estimated from the “diffraction” pattern that the signal attenuation curves exhibit. A different diffraction pattern is observed when the experiment is extended to a larger number (N) of diffusion gradient pulse pairs. Differences in the characteristics of attenuation curves also permit distinguishing different pore shapes and distributions using the N-PFG technique. Using an even number of PFG pairs, an approximation to the average pore size can be obtained even when the sample contains pores with a broad distribution of sizes. Multi-PFG sequences can also be used to differentiate free and multi-compartment diffusion, and to estimate compartment sizes and orientations, and to distinguish microscopic and ensemble anisotropy.
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: April 22, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Evren Ozarslan, Peter J. Basser
  • Crystalline forms of valacyclovir hydrochloride
    Patent number: 7786302
    Abstract: In this invention the novel polymorphs of the valacyclovir hydrochloride and methods for preparing these novel polymorphs are provided.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: August 31, 2010
    Assignee: Eczacibasi-Zentiva Kimyasal Urunler Sanayi Ve Ticaret A.S.
    Inventors: Tuncer Aslan, A. Evren Ozarslan, Filiz Sahbaz, N. Sait Uluozyurt, Nihat Arslan
  • MAGNETIC RESONANCE SPECIMEN EVALUATION USING MULTIPLE PULSED FIELD GRADIENT SEQUENCES
    Publication number: 20100033182
    Abstract: Using pulsed-field-gradient (PFG) sequences, the sizes of the pores in ordered porous media can be estimated from the “diffraction” pattern that the signal attenuation curves exhibit. A different diffraction pattern is observed when the experiment is extended to a larger number (N) of diffusion gradient pulse pairs. Differences in the characteristics of attenuation curves also permit distinguishing different pore shapes and distributions using the N-PFG technique. Using an even number of PFG pairs, an approximation to the average pore size can be obtained even when the sample contains pores with a broad distribution of sizes. Multi-PFG sequences can also be used to differentiate free and multi-compartment diffusion, and to estimate compartment sizes and orientations, and to distinguish microscopic and ensemble anisotropy.
    Type: Application
    Filed: August 11, 2009
    Publication date: February 11, 2010
    Inventors: Evren Ozarslan, Peter J. Basser
  • Process for the preparation of 4-amino-1-hydroxybutylidene-1, 1-biphosphonic acid
    Patent number: 7009071
    Abstract: This invention is related with the preparation of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid with phosphorous acid and phosphorus trichloride in the presence of aralkyl or alkyl ethoxylates or triglycerides such as plant or animal oils or their derivatives; and recovering of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid or salts thereof are described. The main feature of the invention is in the use of the above defined non-ionic emulgators in the phosphonylation reaction.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: March 7, 2006
    Assignee: Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S.
    Inventors: Kadir Dabak, A. Evren Ozarslan, Filiz Sahbaz, Tuncer Aslan
  • Process for the preparation of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid
    Publication number: 20040152916
    Abstract: This invention is related with the preparation of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid with phosphorous acid and phosphorous thrichloride in the presence of aralkyl or akyl ethoxylates or triglycerides such as plant or animal oils or their derivative; and recovering of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid or salts thereof are described. The main feature of the invention is in the use of the above defined non-ionic emulgators in the phosphonylation reaction.
    Type: Application
    Filed: October 10, 2003
    Publication date: August 5, 2004
    Inventors: Kadir Dabak, A Evren Ozarslan, Filiz Sahbaz, Tuncer Aslan