Patents by Inventor A. Francis Stewart

A. Francis Stewart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tyrosine recombinase for genetic engineering
    Patent number: 7083976
    Abstract: The present invention is directed to methods and compositions for TnpI-mediated genetic engineering using the Bacillus thuringiensis recombinase TnpI and the TnpI recombination substrates TRT or TRT?, and variants thereof. In particular, the invention relates to TRT or TRT? sequences, and variants thereof, vectors, cells and kits useful for TnpI-mediated genetic recombination, as well as methods for the use of TRT or TRT? sequences for TnpI-mediated genetic engineering.
    Type: Grant
    Filed: June 30, 2001
    Date of Patent: August 1, 2006
    Assignees: The European Molecular Biology Laboratory, l 'Universite catholique de Louvain
    Inventors: A. Francis Stewart, Youming Zhang, Bernard Hallet
  • Tyrosine recombinase for genetic engineering
    Publication number: 20030113837
    Abstract: The present invention is directed to methods and compositions for TnpI-mediated genetic engineering using the Bacillus thuringiensis recombinase TnpI and the TnpI recombination substrates TRT or TRT′, and variants thereof. In particular, the invention relates to TRT or TRT′ sequences, and variants thereof, vectors, cells and kits useful for TnpI-mediated genetic recombination, as well as methods for the use of TRT or TRT′ sequences for TnpI-mediated genetic engineering.
    Type: Application
    Filed: June 30, 2001
    Publication date: June 19, 2003
    Inventors: A. Francis Stewart, Youming Zhang, Bernard Hallet
  • Methods and compositions for directed cloning and subcloning using homologous recombination
    Patent number: 6355412
    Abstract: The present invention is directed to methods and compositions for DNA subcloning using bacterial recombinase-mediated homologous recombination. The invention relates to methods for cloning, compositions comprising polynucleotides usefall as cloning vectors, cells comprising such polynucleotide compositions, and kits useful for cloning mediated by bacterial recombinases, such as RecE/T and Red&agr;/&bgr;.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: March 12, 2002
    Assignee: The European Molecular Biology Laboratory
    Inventors: A. Francis Stewart, Youming Zhang, Joep Pieter Paul Muyrers