Patents by Inventor A. Geoffrey Skillman

A. Geoffrey Skillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating neurodegenerative disorders using aspartyl protease inhibitors
    Patent number: 7119105
    Abstract: The present invention relates to () non-peptide aspartyl protease inhibitors; (ii) methods for modulating the processing of an amyloid precursor protein (APP); (iii) methods for modulating the processing of a tau protein (?-protein); and (iv) methods for treating neurodegenerative diseases.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: October 10, 2006
    Assignee: The Regents of the University of California
    Inventors: Jonathan A. Ellman, Gary Lynch, Irwin D. Kuntz, Xiaoning Bi, Christina E. Lee, A. Geoffrey Skillman, Tasir Haque
  • Methods for treating neurodegenerative disorders using aspartyl protease inhibitors
    Publication number: 20040157896
    Abstract: The present invention relates to (i) non-peptide aspartyl protease inhibitors; (ii) methods for modulating the processing of an amyloid precursor protein (APP); (iii) methods for modulating the processing of a tau protein (&tgr;-protein); and (iv) methods for treating neurodegenerative diseases.
    Type: Application
    Filed: February 5, 2004
    Publication date: August 12, 2004
    Inventors: Jonathan A. Ellman, Gary Lynch, Irwin D. Kuntz, Xiaoning Bi, Christina E. Lee, A. Geoffrey Skillman, Tasir Haque
  • Nanomolar, non-peptide inhibitors of cathepsin D
    Patent number: 6150416
    Abstract: The present invention provides non-peptide cathepsin D binding compounds and methods for using such compounds in the detection, labelling and inhibition of cathepsin D.
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: November 21, 2000
    Assignee: The Regents of the University of California
    Inventors: Ellen K. Kick, Jonathan A. Ellman, Irwin D. Kuntz, Christina E. Lee, Guangcheng Liu, Diana C. Roe, A. Geoffrey Skillman
  • Heterocyclic derivatives as inhibitors of purine salvage phosphoribosyltransferases
    Patent number: 6075044
    Abstract: The use of certain heterocyclic derivatives for treating parasitic protozoa infections in mammals, in particular bovine trichomoniasis and giardiasis, is disclosed.
    Type: Grant
    Filed: July 17, 1998
    Date of Patent: June 13, 2000
    Assignee: The Regents of the University of California
    Inventors: Ching C. Wang, John Somoza, Jon P. Page, Ronaldus Marcellus Alphonsus Knegtel, Irwin D. Kuntz, Connie M. Oshiro, A. Geoffrey Skillman