Patents by Inventor A. H. Clemens

A. H. Clemens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190134023
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention a so relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Application
    Filed: June 5, 2018
    Publication date: May 9, 2019
    Inventor: Anton H. Clemens
  • Patent number: 9987268
    Abstract: The present invention relates to methods of treating metabolic syndrome Type 2 diabetes mellitus atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: June 5, 2018
    Assignee: NEURENDO PHARMA, LLC
    Inventor: Anton H. Clemens
  • Publication number: 20150065535
    Abstract: The present invention relates to methods of treating metabolic syndrome Type 2 diabetes mellitus atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Application
    Filed: September 8, 2014
    Publication date: March 5, 2015
    Inventor: Anton H. Clemens
  • Publication number: 20140329844
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Application
    Filed: July 18, 2014
    Publication date: November 6, 2014
    Inventor: Anton H. Clemens
  • Patent number: 8829018
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Grant
    Filed: April 10, 2013
    Date of Patent: September 9, 2014
    Assignee: Neurendo Pharma, LLC
    Inventor: Anton H. Clemens
  • Patent number: 8785469
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: July 22, 2014
    Assignee: Neurendo Pharma, LLC
    Inventor: Anton H. Clemens
  • Patent number: 8445508
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: May 21, 2013
    Assignee: Neurendo Pharma, LLC
    Inventor: Anton H. Clemens
  • Patent number: 8399474
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: March 19, 2013
    Assignee: Neurendo Pharma, LLC
    Inventor: Anton H. Clemens
  • Publication number: 20110118293
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Application
    Filed: October 18, 2010
    Publication date: May 19, 2011
    Inventor: Anton H. Clemens
  • Patent number: 7893080
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: February 22, 2011
    Assignee: Neurendo Pharma, LLC
    Inventor: Anton H. Clemens
  • Publication number: 20110034501
    Abstract: The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective ?-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
    Type: Application
    Filed: October 18, 2010
    Publication date: February 10, 2011
    Inventor: Anton H. Clemens
  • Publication number: 20110023214
    Abstract: The convertible mask and cap relates generally to a head cover device for teams, groups, squads, players, companies, troops, sporting events, and more particularly to a unique type of cap that has the option of converting to a face mask when pulled forward from the head to the face.
    Type: Application
    Filed: December 29, 2009
    Publication date: February 3, 2011
    Inventors: Jodine G. Hubbard, Justin D. Peters, Patricia H. Clemens, William R. Clemens
  • Patent number: 6919310
    Abstract: The invention provides an improved method of treating a human suffering from one or more conditions included within the Coronary Heart Disease Risk Factor (CHDRF) syndrome. The method includes administering, by a pharmaceutically effective mode, a drug composition having an opioidergic agent including an opiate antagonist, opiate having ?-agonist activity or combination thereof, and an insulin secretagogue.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: July 19, 2005
    Assignee: CPD, LLC
    Inventor: Anton H. Clemens
  • Patent number: 6846831
    Abstract: Methods of treating a human suffering from the Syndrome of Lipodystrophy or one or more HIV-related abnormalities included therein are provided. One method may include administering, by a pharmaceutically effective mode, a drug composition comprising an opioidergic agent, or alternatively, an opioidergic agent and an insulin secretagogue. The method may also include administering, by a pharmaceutically effective mode, a drug composition comprising an opiate agonist and opiate antagonist, or alternatively, an opiate agonist, opiate antagonist and an insulin secretagogue.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: January 25, 2005
    Assignee: CPD, LLC
    Inventor: Anton H. Clemens
  • Publication number: 20030149076
    Abstract: The invention provides an improved method of treating a human suffering from one or more conditions included within the Coronary Heart Disease Risk Factor (CHDRF) syndrome. The method includes administering, by a pharmaceutically effective mode, a drug composition having an opioidergic agent including an opiate antagonist, opiate having &mgr;-agonist activity or combination thereof, and an insulin secretagogue.
    Type: Application
    Filed: March 3, 2003
    Publication date: August 7, 2003
    Applicant: CPD, LLC
    Inventor: Anton H. Clemens
  • Patent number: 6528520
    Abstract: The invention provides an improved method of treating a human suffering from one or more conditions included within the Coronary Heart Disease Risk Factor (CHDRF) syndrome. The method includes administering, by a pharmaceutically effective mode, a drug composition having an opioidergic agent including an opiate antagonist, opiate having &mgr;-agonist activity or combination thereof, and an insulin secretagogue.
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: March 4, 2003
    Assignee: CPD, LLC
    Inventor: Anton H. Clemens
  • Publication number: 20030036546
    Abstract: Methods of treating a human suffering from the Syndrome of Lipodystrophy or one or more HIV-related abnormalities included therein are provided. One method may include administering, by a pharmaceutically effective mode, a drug composition comprising an opioidergic agent, or alternatively, an opioidergic agent and an insulin secretagogue. The method may also include administering, by a pharmaceutically effective mode, a drug composition comprising an opiate agonist and opiate antagonist, or alternatively, an opiate agonist, opiate antagonist and an insulin secretagogue.
    Type: Application
    Filed: June 25, 2002
    Publication date: February 20, 2003
    Applicant: CPD, LLC
    Inventor: Anton H. Clemens
  • Publication number: 20020045572
    Abstract: The invention provides a method of treating a human suffering from the Syndrome of Type 2 Diabetes by administering, by a pharmaceutically effective mode, a drug composition having an opioidergic agent including opiates having &mgr;-agonist activity, opiates having &kgr; antagonist activity or a combination thereof and an insulin secretagogue.
    Type: Application
    Filed: June 11, 2001
    Publication date: April 18, 2002
    Applicant: CPD, LLC
    Inventor: Anton H. Clemens
  • Publication number: 20020045636
    Abstract: The invention provides an improved method of treating a human suffering from one or more conditions included within the Coronary Heart Disease Risk Factor (CHDRF) syndrome. The method includes administering, by a pharmaceutically effective mode, a drug composition having an opioidergic agent including an opiate antagonist, opiate having &mgr;-agonist activity or combination thereof, and an insulin secretagogue.
    Type: Application
    Filed: June 11, 2001
    Publication date: April 18, 2002
    Applicant: CPD, LLC
    Inventor: Anton H. Clemens
  • Patent number: 6262062
    Abstract: A method of treating a human suffering from one or more conditions included within the Coronary Heart Disease Risk Factor (CHDRF) syndrome. The method includes administering, by a pharmaceutically effective mode, a drug composition having an active ingredient which is selected from opiate antagonists, opiates having &mgr; agonist activity and combinations thereof.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: July 17, 2001
    Assignee: CPD, LLC
    Inventor: Anton H. Clemens