Abstract: A system for cooling a heat generating component of a vehicle. The system includes a blower of a vehicle heating, ventilation, and air conditioning (HVAC) system. An air duct extends from the blower to the heat generating component to cool the heat generating component.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: A system for cooling a heat generating component of a vehicle. The system includes a blower of a vehicle heating, ventilation, and air conditioning (HVAC) system. An air duct extends from the blower to the heat generating component to cool the heat generating component.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticcacaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticcacaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: The present disclosure provides a casing for an air conditioning unit including a main body, a door, a passing defining member, and a drain channel. The main body includes a fresh-air passage and a recirculation-air passage. The recirculation-air passage is positioned below the fresh-air passage. The door selectively opens and closes a communication hole through which the fresh-air passage and the recirculation-air passage are in fluid communication with each other. The passage defining member is disposed upstream of the communication hole and defines a lower side of the fresh-air passage. The drain channel extends from the passage defining member to a space outside of the recirculation-air passage to discharge condensed water generated in the fresh-air passage.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticcacaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticcacaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: The present disclosure provides a casing for an air conditioning unit including a main body, a door, a passing defining member, and a drain channel. The main body includes a fresh-air passage and a recirculation-air passage. The recirculation-air passage is positioned below the fresh-air passage. The door selectively opens and closes a communication hole through which the fresh-air passage and the recirculation-air passage are in fluid communication with each other. The passage defining member is disposed upstream of the communication hole and defines a lower side of the fresh-air passage. The drain channel extends from the passage defining member to a space outside of the recirculation-air passage to discharge condensed water generated in the fresh-air passage.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: A fastening device for securing a first component to a second component includes a latch coupled with the first component and a catch coupled with the second component. The fastening device further includes a convex portion formed with one of the latch and the catch and a concave portion formed with the other of the latch and the catch. The catch is configured to engage with the latch when the concave portion receives the convex portion.

Abstract: A dual joint block for pressing a seal against an air conditioner thermal expansion valve housing. The dual joint block includes a body having an inner face and an outer face. The body defines a first aperture and a second aperture. The first aperture extends through the body between the inner face and the outer face. The first aperture is configured to completely surround a first conduit extending therethrough. The second aperture extends through the body between the inner face and the outer face, and is configured to completely surround a second conduit extending therethrough.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: A dual joint block for pressing a seal against an air conditioner thermal expansion valve housing. The dual joint block includes a body having an inner face and an outer face. The body defines a first aperture and a second aperture. The first aperture extends through the body between the inner face and the outer face. The first aperture is configured to completely surround a first conduit extending therethrough. The second aperture extends through the body between the inner face and the outer face, and is configured to completely surround a second conduit extending therethrough.

Abstract: An induction forging coil apparatus which makes induction forge coils easier and faster to change on a forge-line. The coil insert is a separate independent unit by itself which slides into the frame to connect to the frame via bus connections and other components. The coil insert is attached to the frame (another separate independent unit by itself) to complete the overall induction heating coil. The induction coil (with both units attached and operatively interconnected) can run on the forge line until it blows/fails, and instead of pulling the whole induction coil (both units attached) off-line to be rebuilt; the frame can be left on-line (or pulled off-line for a brief period of time if there is not enough room to reach the components due to the particular forge-line setup) to switch the failed insert with a new or rebuilt insert, by disconnecting the failed coil insert from the frame and then reconnecting the frame with the new or rebuilt coil insert.

Abstract: A compound of formula (I): or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof. Methods of inhibiting 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. Methods of treating non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.