Abstract: An electrical heating system for a vehicle. The system includes: a transparent metallic layer configured to be mounted to a transparent material, conduct electrical current, and increase in temperature to heat the transparent material in response to electrical current running across the transparent metallic layer; a power supply; a heating, ventilation, and air conditioning (HVAC) system configured to heat and cool a passenger cabin of the vehicle; and a control module. The control module is configured to: apply voltage from the power supply to the transparent metallic layer to heat the transparent material; and apply voltage from the power supply to a component of the HVAC system to heat the component of the HVAC system.

Abstract: A system for electrically heating glass configured for installation on a vehicle. The system includes: a transparent metallic layer configured to be mounted to the glass, conduct electrical current, and increase in temperature to heat the glass in response to electrical current running across the transparent metallic layer; a glass temperature sensor configured to sense a glass temperature of the glass; a humidity sensor configured to sense humidity of at least one of cabin humidity inside the vehicle and exterior humidity outside of the vehicle; a cabin temperature sensor configured to sense cabin temperature of the vehicle; an exterior temperature sensor configured to sense exterior temperature outside of the vehicle; and a control module.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: The present disclosure provides ubonodin peptides, pharmaceutical formulations comprising ubonodin peptides and nucleic acids encoding ubonodin peptides. The disclosure also provides methods of treating Burkholderia infections in a subject in need thereof utilizing the described ubonodin peptides and pharmaceutical formulations.

Abstract: A system for cooling a heat generating component of a vehicle. The system includes a blower of a vehicle heating, ventilation, and air conditioning (HVAC) system. An air duct extends from the blower to the heat generating component to cool the heat generating component.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: A system for cooling a heat generating component of a vehicle. The system includes a blower of a vehicle heating, ventilation, and air conditioning (HVAC) system. An air duct extends from the blower to the heat generating component to cool the heat generating component.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticcacaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticcacaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: The present disclosure provides a casing for an air conditioning unit including a main body, a door, a passing defining member, and a drain channel. The main body includes a fresh-air passage and a recirculation-air passage. The recirculation-air passage is positioned below the fresh-air passage. The door selectively opens and closes a communication hole through which the fresh-air passage and the recirculation-air passage are in fluid communication with each other. The passage defining member is disposed upstream of the communication hole and defines a lower side of the fresh-air passage. The drain channel extends from the passage defining member to a space outside of the recirculation-air passage to discharge condensed water generated in the fresh-air passage.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticcacaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticcacaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: The present disclosure provides a casing for an air conditioning unit including a main body, a door, a passing defining member, and a drain channel. The main body includes a fresh-air passage and a recirculation-air passage. The recirculation-air passage is positioned below the fresh-air passage. The door selectively opens and closes a communication hole through which the fresh-air passage and the recirculation-air passage are in fluid communication with each other. The passage defining member is disposed upstream of the communication hole and defines a lower side of the fresh-air passage. The drain channel extends from the passage defining member to a space outside of the recirculation-air passage to discharge condensed water generated in the fresh-air passage.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: A fastening device for securing a first component to a second component includes a latch coupled with the first component and a catch coupled with the second component. The fastening device further includes a convex portion formed with one of the latch and the catch and a concave portion formed with the other of the latch and the catch. The catch is configured to engage with the latch when the concave portion receives the convex portion.

Abstract: A dual joint block for pressing a seal against an air conditioner thermal expansion valve housing. The dual joint block includes a body having an inner face and an outer face. The body defines a first aperture and a second aperture. The first aperture extends through the body between the inner face and the outer face. The first aperture is configured to completely surround a first conduit extending therethrough. The second aperture extends through the body between the inner face and the outer face, and is configured to completely surround a second conduit extending therethrough.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.