Abstract: A cable pass through system for running one or more cables through a roof and a ceiling can comprise a cap having an inner surface and an outer surface having a thickness which can create a shell. The cap can cover and attach to a base. The seals can be attached to the base and the cap forming a seal around the cable. A gasket can be placed between the base and the roof creating a seal between the roof and the base. A backing plate can be placed on the ceiling and is removably attached to the base by one or more fasteners. The cap and the base can further comprise a recess for the one or more seals and a seal can be placed in the recess in the base wherein when pushed together the two seals create a watertight seal against the cable.

Abstract: The present invention generally relates to bacterial polypeptide display systems, libraries using these bacterial display systems, and methods of making and using these systems, including methods for improved display of polypeptides on the extracellular surface of bacteria using circularly permuted transmembrane bacterial polypeptides that have been modified to increase resistance to protease degradation and to enhance polypeptide display characteristics.

Abstract: The invention relates generally to polypeptides that include at least a first cleavable moiety (CM1) that is a substrate for at least one matrix metalloprotease (MMP) and at least a second cleavable moiety (CM2) that is a substrate for at least one serine protease (SP), to activatable antibodies and other larger molecules that include these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease, and to methods of making and using these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: The invention relates generally to antibodies that bind programmed death ligand 1 (PDL1), activatable antibodies that specifically bind to PDL1 and methods of making and using these anti-PDL1 antibodies and anti-PDL1 activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: The invention relates generally to polypeptides that include at least a first cleavable moiety (CM1) that is a substrate for at least one matrix metalloprotease (MMP) and at least a second cleavable moiety (CM2) that is a substrate for at least one serine protease (SP), to activatable antibodies and other larger molecules that include these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease, and to methods of making and using these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: A coated plier hand tool with a fixed loop provided in a handle grip to promote security of the tool via tether to a work belt, work vest, work bag or similar receiving article, and methods for fabricating such tool.

Abstract: Compositions for treating a substrate to provide increased lubricity to portions of the substrate surface that come into contact with the surface of a mating component are provided. The treated substrates provide improved lubricity, while maintaining adhesion between the surface of the substrate and an overlying polymer coating and imparting corrosion resistance to the substrate surface. The compositions include a silanol coupling agent in combination with lubricating particles, and an acid, which are dissolved or dispersed in a mixture of organic solvent and water.

Abstract: An outdoor decorative burner having a direct gas feed and a linear burner having a plurality of longitudinally-oriented slit-like flame orifices. The linear burner is securely attached to a plate by at least two wrap brackets. A direct spark igniter and a flame sensor are included and surrounded by protective cages.

Abstract: The present invention is directed to a microelectrode array for use in microengineered physiological systems and methods of using the same.

Abstract: The invention relates generally to polypeptides that include at least a first cleavable moiety (CM1) that is a substrate for at least one matrix metalloprotease (MMP) and at least a second cleavable moiety (CM2) that is a substrate for at least one serine protease (SP), to activatable antibodies and other larger molecules that include these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease, and to methods of making and using these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one protease selected from matriptase and u-plasminogen activator (uPA), to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one protease selected from matriptase and u-plasminogen activator, and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one protease selected from matriptase and u-plasminogen activator in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: An outdoor decorative burner having a direct gas feed and a linear burner having a plurality of longitudinally-oriented slit-like flame orifices. The linear burner is securely attached to a plate by at least two wrap brackets. A direct spark igniter and a flame sensor are included and surrounded by protective cages.

Abstract: A writing instrument with a cap that lockingly engages a body portion via a locking assembly is presented herein. The locking assembly includes a pair of locking tabs on the cap that correspondingly fit within locking channels on the body of the writing instrument. With the tabs positioned within the locking channels, the cap is twisted or rotated such that the locking tabs slide past a node within the channels and restricts removal of the cap from the body portion.

Abstract: A condensation cooling system for motor vehicles is presented. The system, in principal part, comprises a liquid-to-liquid heat exchanger for circulating a first coolant, a coolant tank for circulating a second coolant, and a condensing panel or surface, where the condensing panel is part of the coolant tank and also functions as a vehicle body panel. These components are arranged in two circuits, i.e. an engine cooling circuit in which a first coolant is circulated and a vapor condensing circuit in which a second coolant is circulated. The two cooling circuits are interconnected by the coolant tank where the heat exchanger is positioned within the coolant tank such that it is immersed in the second coolant. The coolant tank may also be equipped with pressure release valves, electric fans and diffuser plates to control pressure and manage air and vapor flow internally within the tank.

Abstract: A poolside burner having a central gas feed and a burner ring having longitudinally-oriented slit-like flame orifices. The burner ring is securely attached to a burner plate having a centralized hole through which a feeder extends and mates with a central distribution tube connected to the burner ring.

Abstract: The present invention generally relates to bacterial polypeptide display systems, libraries using these bacterial display systems, and methods of making and using these systems, including methods for improved display of polypeptides on the extracellular surface of bacteria using circularly permuted transmembrane bacterial polypeptides that have been modified to increase resistance to protease degradation and to enhance polypeptide display characteristics.

Abstract: The invention provides methods and kits for qualitatively and/or quantitatively analyzing activation and other properties of activatable antibody therapeutic in biological samples, including tissues and/or biofluid samples. The invention also relates to methods of using a capillary-based immunoassay platform to qualitatively and/or quantitatively analyze levels of activation in biological samples, including tissues and/or biofluid samples.

Abstract: One or more embodiments disclosed herein relate generally to flotation devices, and more specifically to modular flotation devices with a mechanism to removably attach to other modular devices. In one embodiments, an apparatus includes a first flotation module and a first connector coupled to the first flotation module. The first connector has a first end portion, a second end portion and a sidewall extended from the first end portion to the second end portion. The sidewall defines a plurality of circumferentially defined stepped portions configured to matingly engage a second connector of a second flotation module to couple the first flotation module to the second flotation module. The first connector is selectively operative as one of a female connector or a male connector with respect to the second connector.

Abstract: The present disclosure generally relates to a cell culturing system, and specifically to a three-dimensional cell culturing system for neuronal cells that promotes both structural and functional characteristics that mimic those of in vivo peripheral fibers, including cell myelination. Using a dual hydrogel construct and spheroids comprising neuronal cells, the present disclosure provides methods, devices, and systems for in vitro spatially-controlled, three-dimensional models that permit intra- and extra-cellular electro-physiological measurements and recordings. The three-dimensional hydrogel constructs allow for flexibility in incorporated cell types, geometric fabrication, and electrical manipulation, providing viable systems for culture, perturbation, and testing of biomimetic neural growth with physiologically-relevant results.