Abstract: A multi-tool is provided having a plurality of tool-receipt openings adapted to receive respective tools, wherein at least one of the tools is a slitting punch. In some cases, the slitting punch can be centrally positioned/oriented in the multi-tool. The multi-tool includes a guide plate configured to connect a driver assembly of the multi-tool and a selected one of the tools of the multi-tool via a drive mechanism. In some cases, the guide plate has a plurality of openings through which protruding portions of the drive mechanism correspondingly extend. One or more of the protruding portions extending through the guide plate openings are positioned in front of the desired tool-receipt opening. Adjustment of the drive mechanism can result from corresponding adjustment of the guide plate and/or corresponding adjustment of the driver assembly head.

Abstract: Endoscopic imaging systems are disclosed herein. In some embodiments, an endoscopic imaging system can include an endoscope having a distal tip with a distal face configured to face a scene, such as a portion of a body cavity of a patient. The endoscope can further include first cameras for capturing first image data of the scene, a projector for projecting a light pattern into the scene, and second cameras for capturing second image data of the scene including the light pattern. A processor can be communicatively coupled to the first and second cameras for receiving the first and second image data. The processor can process the first and second image data to generate an image of the scene at the perspective of a virtual camera, and can vary the perspective, the aperture, the focus plane, and/or another parameter of the virtual camera without requiring the endoscope to be physically moved.

Abstract: A magnetic particle separation system includes a magnetic field generating device having an upper surface with a receiving area formed thereon; and a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface. A container assembly is disposed on the upper surface and includes: a flexible container having an outer wall with an interior surface that at least partially bounds an internal compartment, the outer wall having a front side and an opposing back side with the internal compartment disposed therebetween; a fluid inlet extending through the outer wall at the front side; a fluid outlet extending through the outer wall at the front side; and a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet.

Abstract: Described are techniques for a control plane. The techniques include receiving, at the control plane hosted on a service-provider data center, a request to perform a computing resource operation at a remote data center, where the control plane is used to manage computing resources located at the remote data center. The techniques further include creating a data object at the service-provider data center to represent a status of the computing resource operation, and updating the data object in response to receiving indications of events associated with performance of the computing resource operation at the remote data center. The techniques further include receiving, at the control plane, a status request for the computing resource operation, querying the data object maintained at the service-provider data center for the status of the computing resource operation, and providing the status of the computing resource operation represented by the data object.

Abstract: Exemplary embodiments pertain to a solution containing carbon black. The solution may be applied to a membrane filter of a microbial enumeration system as a post-rinse solution (i.e., after the membrane filter is rinsed with the sample of interest). The solution may reduce or suppress background autofluorescence, thereby improving detection and enumeration of colony forming units (CFUs) or other microbiological entities. The solution may be used in connection with a method for performing sample preparation for a microbial enumeration system. The carbon black solution may be manufactured according to a manufacturing process detailed herein.

Abstract: The present application provides compounds that may be used as a glucagon-like peptide-1 receptors (GLP-1R) agonist, or pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions containing such compounds, or pharmaceutically acceptable salts thereof. Methods of preparing these compounds and compositions, and methods of using these compounds and compositions to treat or prevent a disease or a condition mediated by GLP-1R, are also provided.

Abstract: A steering column assembly includes a steering wheel having a steering wheel rim, a steering wheel hub, and a rim extension segment. The steering column assembly also includes a motor operatively coupled to the rim extension segment. The steering column assembly further includes a jacket assembly operatively coupled to the steering wheel, wherein the jacket assembly defines a central passage extending in a longitudinal direction of the steering column assembly, wherein the central passage does not include a steering shaft therein.

Abstract: An apparatus includes a first and second elongate member that can releasably couple together to in order to cooperate to clamp and staple tissue, a clamp lever and latch body that together can latch the first and second elongate member to clamp tissue, a firing assembly that can sever and staple clamped tissue, and a lockout assembly that can prevent firing of the firing assembly until the clamp leer and latch body successfully latch the first and second elongate member together to clamp tissue.

Abstract: An implant insertion tool includes an outer shaft, an inner shaft received in the outer shaft, and two arms coupled to the outer shaft and the inner shaft. The inner shaft translates within the outer shaft and has angled ramps that slide within complementary angled ramps in the two arms. The arms engage an implant for insertion into a body. When the inner shaft translates along a longitudinal axis, it causes the angled ramps to slide against the complementary angled ramps in the arms such that the two arms move laterally relative to the longitudinal axis of the outer shaft to engage and disengage the implant.

Abstract: A system is disclosed. The system may include two devices, along with a processor to communicate with the two devices. A buffer may store an entry including a communication from one device to the other device.

Abstract: Described are coated particles containing a core and a coating, and pharmaceutical formulations containing these coated particles. The core contains a polymer or a hydrophobic drug. The coating contains a glycoprotein or a combination of a sugar and a protein. The coating surrounds the core. The coated particles are effectively absorbed by mucosa such as intestinal mucosa, GI tissue, and/or vaginal mucosa, and show increased systemic uptake following oral or mucosal administration. Optionally, the coated particles contain one or more active agents encapsulated in the core and/or embedded in the coating of the particles, for systemic or local delivery.

Abstract: In some aspects, the present disclosure provides hydrogels that comprise a crosslinked reaction product of (a) a reactive multi-arm polymer that comprises a plurality of reactive moieties and (b) a multifunctional crosslinking compound which has plurality of complementary reactive moieties that are reactive with the reactive moieties of the reactive multi-arm polymer, the hydrogels comprising hydrolysable moieties as described herein that are dispersed throughout the hydrogels. Other aspects of the present disclosure pertain to reactive multi-arm polymers and multifunctional crosslinking compounds for forming such hydrogels and to crosslinkable systems for forming such hydrolysable hydrogels.

Abstract: Laser drivers and methods are disclosed including a pulse input for receiving one or more logical pulse control signals, a delay circuit, a main pulse output, and a precharge pulse output for efficiently driving a laser with reduced time delay to desired optical output and reduced power consumption during between optical outputs.

Abstract: In general, this disclosure describes techniques that enable a network system to perform application-aware active measurement for monitoring network health. The network system includes memory that stores a topology graph for a network. The network system includes processing circuitry that may receive an identifier associated with an application utilizing the network for communications, and determine, based on the topology graph and the identifier, a subgraph of the topology graph based on a location, in the topology graph, of a node representing a compute node that is a host of the application. The processing circuitry may next determine, based on the subgraph, a probe module to measure performance metrics associated with the application, and for the probe module, generate configuration data corresponding to the probe module. The processing circuitry may output, to the probe module, the configuration data.

Abstract: Described herein are systems and techniques for implementing a petrophysics assistant. An example method can include receiving, by a control language model configured to perform natural language processing, a query related to one or more subject areas; based on the one or more subject areas associated with the query and a respective domain-specific knowledge of each domain-specific language model from a plurality of domain-specific language models, selecting one or more domain-specific language models from the plurality of domain-specific language models to answer the query; sending, to the one or more domain-specific language models, a request to answer the query; and generating, by the control language model, a response to the query based on one or more responses to the query received from the one or more domain-specific language models.

Abstract: Described herein is an animal kill trap. More specifically, an improved animal trap configured for trapping and humanely killing small mammalian predators. The trap comprises an integrated enclosure which utilizes the lid for setting the trap mechanism, and additionally acts as a safety mechanism wherein when the lid is the open position, the trap is deactivated and thus avoiding any harm to the user. The trap comprises a tunnel architecture which is appealing to the predators, and additionally has a capture flag to indicate when a predator has been captured.

Abstract: A method of assigning parent-of-origin to a haplotype, a sub-haplotype or an allele associated with a haplotype. Chromosome-length haplotypes of a genome are generated and a differential methylation status of at least one imprinted differentially methylated region (iDMR) associated with each one of the autosomal chromosomes is determined. The differential methylation status of the at least one iDMR is used to assign parent-of-origin for each one of the chromosome-length haplotypes.

Abstract: The present application provides compounds that may be used as a glucagon-like peptide-1 receptors (GLP-1R) agonist, or pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions containing such compounds, or pharmaceutically acceptable salts thereof. Methods of preparing these compounds and compositions, and methods of using these compounds and compositions to treat or prevent a disease or a condition mediated by GLP-1R, are also provided.

Abstract: An apparatus includes a first and second elongate member that can releasably couple together to in order to cooperate to clamp and staple tissue, a latch member that can latch the first and second elongate member to clamp tissue, a firing assembly that can sever and staple clamped tissue, and a clamp force measuring assembly. The clamp force measuring assembly can measure a parameter associated with a clamping force imparted on the first and second stapling surfaces while clamping tissue, and process and communicate the measured parameter to be compared with a predetermined limit associated with successful staple formation.

Abstract: A syngas generation system includes a molten carbonate fuel cell (MCFC) including a MCFC cathode configured to receive a MCFC cathode input stream including a flue gas stream and a MCFC anode configured to output a MCFC anode exhaust stream including carbon dioxide and steam. The syngas generation system further includes a solid oxide electrolysis cell (SOEC) including an SOEC cathode and an SOEC anode. The SOEC is configured to receive, at the SOEC cathode, an SOEC cathode input stream, the SOEC cathode input stream including at least a portion of the MCFC anode exhaust stream, co-electrolyze carbon dioxide and steam in the SOEC cathode input stream, and output, from the SOEC cathode, an SOEC cathode exhaust stream including carbon monoxide and hydrogen gas.