Abstract: A cysteinized variant of an RNase disclosed in U.S. Pat. No. 6,239,257 B1 is disclosed. A targeting moiety can be conjugated to the cysteine residue.

Abstract: A fusion protein contains a cysteinized variant of an RNase disclosed in U.S. Pat. No. 6,239,257 B1.

Abstract: A method and system for mirror storage element resynchronization in a storage virtualization device is disclosed. According to one embodiment of the present invention, a read operation on a region of a data volume is received at a first module of a first storage virtualization device where the data volume is associated with at least a first mirror storage element and a second mirror storage element, a state indicated by a bit corresponding to the region of the data volume within a first synchronization map is determined in response to receiving the read operation, the read operation is processed using the first module if the bit is determined to indicate a first state and using a second module of the first storage virtualization device if the bit is determined to indicate a second state.

Abstract: Methods for recombinantly producing new RNases, as well as previously-known RNases, are disclosed. The new RNases are active against human carcinoma cells.

Abstract: The development of an in vitro regeneration system that utilizes a plant growth regulator having cytokinin activity for the induction of de novo shoots or somatic embryos on explants of phytopharmaceutical plants is provided. Transfer of the regenerated shoots or somatic embryos into a solid or liquid medium with no plant growth regulators results in the rapid and prolific growth of viable plantlets. The method and its modifications are intended for application to all phytopharmaceutical plants, in particular St. John's wort (Hypericum perforatum cv. Anthos), Huang-qin (Scutellaria baicalensis), Echinacea sp., Feverfew (Tanacetum parthenium), garlic (Allium sp.) and the like. Furthermore, a process for the uptake of nutrients, minerals or additives from the growth medium and accumulation of these in the consumable biomass of plants, hereafter referred to as phytofortification, is also described.

Abstract: The present invention provides a process for the extraction of aromatics from petroleum fractions i.e. naphtha, kerosene and gas oil, using re-extraction route for recovery of solvent.

Abstract: Ribonuclease DNA coding for an amino acid sequence beginning with a residue of glutamine is introduced into a vector of pET22b(+) plasmid to form recombinant plasmid DNA that begins with a Pel B leader sequence. The recombinant plasmid DNA is used to transform an E.coli BL21(DE3) host. Signal peptidase enzyme present in the host cell cleaves the pelB leader sequence during signal processing and thereby allows the glutamine residue to autocyclize to pyroglutamic acid. In this way, the Ribonuclease can be produced directly, i.e. without a separate step of cleaving the initial N-terminal methionine residue.

Abstract: The present invention provides a synergistic composition of bioactive fraction essentially constituting iridoid glucosides, acetyl barlerin and shanzhiside methyl ester isolated from a plant source Barleria prionitis linn along with a process for the isolation of the bioactive fraction, the present invention also relates to a method of treating mammals and humans for hepatotoxicity, stress and immuno-deficiency with the synergistic bioactive composition.

Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.

Abstract: The present invention provides a synergistic composition of bioactive fraction essentially constituting iridoid glucosides, acetyl barlerin and shanzhiside methyl ester isolated from a plant source Barleria prionitis linn along with a process for the isolation of the bioactive fraction, the present invention also relates to a method of treating mammals and humans for hepatotoxicity, stress and immuno-deficiency with the synergistic bioactive composition.

Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising_of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.

Abstract: Following initial call establishment negotiation to build a call context between a network and a remote unit, the base processes the header of the data packets. The base acts as an intermediate nodal point to establish call contexts with the endpoints on the traffic channels, wherein the processing of the header of the data packets is terminated at the base. The base processes only the header field that needs to be transmitted along the payload, and transfers the processed portion along with the payload. A session is then established between the remote unit and the network, and the traffic resumes from both ends.

Abstract: pET11d-rOnc(Q1, M23L) DNA is subjected to two different site-directed mutations, each using an overlapping PCR protocol. One of the site-directed mutations changes the amino acid residue at position 23 of the encoded protein from leucine to methionine, whereby the encoded protein can be made into ranpirnase by cleaving the N-terminal methionine residue and allowing the adjacent glutamine residue to autocyclize. The other site-directed mutation changes the amino acid residue at position 72 of the encoded protein from serine to cysteine, thereby producing an encoded protein that can be made into a cysteinized ranpirnase by cleaving the N-terminal methionine residue and allowing the adjacent glutamine residue to autocyclize.

Abstract: A process for effectively remediating soils contaminated with individual or mixture of metal ions is described. The process involves utilizing plants of the genus Pelargonium, particularly Pelargonium sp., to hyperaccumulate metal ions in their roots and shoots. These plants when grown on soils, which contain one or more of the metal ions, individually or in a complex mixture, will uptake the metal ions through their roots and translocate them to the shoots. This process thereby removes the metal ions from the soil. The harvested shoot and root biomass can be used for extraction of essential aromatic oils, and the residual oil-extracted biomass will be available for extraction and recycling of the metals. The process also describes the use of the above said plant(s) for remediating land-farming sites of petroleum industries, which are generally contaminated with a mixture of metal ions and organic contaminants.

Abstract: pET11d-rOnc(Q1, M23L) DNA is subjected to two different site-directed mutations, each using an overlapping PCR protocol. One of the site-directed mutations changes the amino acid residue at position 23 of the encoded protein from leucine to methionine, whereby the encoded protein can be made into ranpirnase by cleaving the N-terminal methionine residue and allowing the adjacent glutamine residue to autocyclize. The other site-directed mutation changes the amino acid residue at position 72 of the encoded protein from serine to cysteine, thereby producing an encoded protein that can be made into a cysteinized ranpirnase by cleaving the N-terminal methionine residue and allowing the adjacent glutamine residue to autocyclize.

Abstract: The invention concerns a method for control of the properties of the remaining oil layer on magnesium or magnesium alloy particles and/or other reactive metal particles produced from molten metal. The particles are cooled in a cooling oil with subsequent centrifuging and heating to remove remaining oil. A part of the oil layer on the particles is replaced with a lighter oil, preferably during centrifuging. The oil can be supplied as a spray. The light oil is supplied in an amount of 0.5-10 weight %. The light oil used should have a viscosity <5 cP at 25.degree. C. and a flashpoint <100.degree. C. Preferably it is used oils having a viscosity <2.5 cP and a flash point between 30.degree. and 75.degree. C. It is preferred to use dearomatized oil.

Abstract: A plurality of viable plant regenerants can be produced by culturing an intact plant seed of in the presence of cytokinin and/or auxin growth factors. The growth factor is preferably benzylaminopurine and thiadiziron. The plant seed is preferably a pea, bean, geranium, peanut, grass pea, chickpea or lentil seed.

Abstract: The method and apparatus for improving linearization of a radio frequency power amplifier which includes extracting a small portion of the output signal of the power amplifier and utilizing this extracted signal as a feedback signal. The feedback signal is then adjusted in phase, attenuated, and combined with the input signal of the power amplifier and then filtered prior to being transmitted to the power amplifier.

Abstract: Reactive metal granules, especially of magnesium and/or magnesium alloys, are produced directly from molten metal. The metal is fed under pressure to a granulation nozzle which forces the metal to acquire a circular motion of increasing velocity before it reaches the outlet of the nozzle and disintegrates successively into small fragments and droplets. These fragments and droplets are formed in an inactive gas atmosphere in an enclosed system and are thereafter solidified and cooled in a nonoxidizing cooling bath. An apparatus includes a granulation chamber made up of two parts which can be fitted to each other at various positions with an air tight locking system.

Abstract: A method for the treatment of waste products, in particular oil-contaminated chips of reactive metals such as magnesium and magnesium alloys includes heading the chips to a temperature close to or above the boiling point of the oil and below the melting point of the metal. Preferably, a closed, cylindrical rotating furnace having inner, slanting blades/wings on the wall of a furnace is used. Chips are fed from a container via a transporting device into the furnace. A closed outlet system conducts the chips from the furnace. Oil vapour is conducted out of the furnace and is coalesced.