Abstract: The present technology is generally directed to adjustable shunting systems for draining fluid from a first body region to a second body region. The adjustable shunting systems include a flow control plate or cartridge for controlling the flow of fluid through the system. For example, the flow control plate can include a shape memory actuation assembly having one or more nitinol actuators for controlling the flow of fluid through the system. The flow control plate can further include a plurality of discrete sheets or layers adhered together to encase the shape memory actuation assembly. The discrete sheets or layers can form flow channels for directing fluid through the flow control plate.

Abstract: Communications over short-range connections are used to facilitate whether access to resources is to be granted. For example, upon device discovery of one of an electronic user device and an electronic client device by the other device over a Bluetooth Low Energy connection, an access-enabling code associated with a user device or account can be evaluated for validity and applicability with respect to one or more particular resource specifications. User identity can be verified by comparing the user against previously obtained biometric information.

Abstract: An apparatus for treating an aneurysm includes an occlusion element configured to be releasably coupled to an elongate delivery shaft and having a distal end, a proximal end, and a longitudinal axis extending between the distal end and the proximal end, the occlusion element configured to be delivered in a collapsed configuration and further configured to expand to an expanded configuration, the occlusion element comprising an inverted mesh tube having an outer layer and an inner layer, the outer layer transitioning to the inner layer at an inversion fold located at or adjacent the distal end of the occlusion element, the inversion fold defining an inner diameter, the occlusion element further comprising a maximum outer diameter, wherein the inner diameter is between about 35% to about 85% of the maximum outer diameter, and wherein an outer diameter of the occlusion element increases along the longitudinal axis to the maximum outer diameter.

Abstract: The present technology relates to adjustable shunting systems and methods. In some embodiments, the present technology includes an adjustable shunting system that includes a drainage element having an inflow portion configured for placement within a patient. The system can also include a flow control assembly having a gating element operably coupled to the outflow portion of the drainage element. The flow control assembly can further include a first actuation element and a second actuation element coupled to the gating element. The first and second actuation elements can be configured to selectively move the gating element relative to the outflow portion to control an amount of fluid flow therethrough. The first and second actuation elements can each extend less than entirely around a perimeter of the drainage element.

Abstract: In one embodiment, the present disclosure is directed to a bathroom mirror lighting system comprising a mirror, a light source, a sensor, and a control circuit operably coupled to the light source and the sensor. The control circuit receives a sensor signal from the sensor indicative of at least one of a user's distance from the sensor, a user's position, a user's posture, a motion of the user towards or away from the sensor, or a task being performed by the user. The control circuit then transmits a control signal to the light source causing the light source to alter its light output based on the sensor signal from the sensor.

Abstract: In an embodiment, systems and methods for reviewing payments using artificial intelligence are provided. Training data is collected that includes payments made by insurance payors for claims received from medical providers. The payments may have been verified as correct and include metadata about the associated claim such as the medical service and whether the claim was in or out of network. The training data is used to train a model that predicts a payment amount for a claim from a medical provider for an insurance payor. When a payment is received, the model is used to predict the payment amount for the payment. The predicted amount is compared with the actual payment amount and is used to determine if the payment is anomalous. If the payment is anomalous, it is provided to an auditor who checks the payment for compliance with a contract between the payor and the provider.

Abstract: Described herein are methods for coordinating movement of a group of people, comprising: receiving numerical coordinates for each count of a drill for each person in a group of people, wherein the numerical coordinates indicate a location on a field for each person; receiving a starting count for each of the one or more sets and a number of counts in each of the one or more sets for each person; combining the numerical coordinates with the start count and the number of counts for each of the one or more sets; deriving human readable coordinates for each count of the drill for each person, wherein the human readable coordinates indicate the location on the field for each person; and transmitting the human readable coordinates to one or more receiving devices each associated with one person in the group of people.

Abstract: A cache may include multiple request handling pipes, each of which may further include multiple request buffers, for storing device requests from one or more processors to one or more devices. Some of the device requests may require to be sent to the devices according to an order. For a given one of such device requests, the cache may select a request handling pipe, based on an address indicated by the device request, and select a request buffer, based on the available entries of the request buffers of the selected request handling pipe, to store the device request. The cache may further use a first-level and a second-level token stores to track and maintain the device requests in order when transmitting the device requests to the devices.

Abstract: An inflatable crate assembly includes a base panel, a rear panel, a first side panel, a second side panel, and a top panel, where: the base panel, the rear panel, the first side panel, the second side panel, and the top panel are all formed from a single piece of drop stitch material; an inner wall of the drop stitch material forms at least a portion of an interior surface of the inflatable crate assembly; and an outer wall of the drop stitch material forms at least a portion of an exterior surface of the inflatable crate assembly; and the inflatable crate also includes a drop stitch corner formed between each of the rear panel and the base panel, the first side panel and the base panel, the top panel and the first side panel, and the second side panel and the top panel.

Abstract: A method of identifying a subject having cancer who is likely to be responsive to a treatment compound, comprising administering the treatment compound to the subject having the cancer; obtaining a sample from the subject; determining the level of a biomarker in the sample from the subject; and diagnosing the subject as being likely to be responsive to the treatment compound if the level of the biomarker in the sample of the subject changes as compared to a reference level of the biomarker; wherein the treatment compound is Compound 1, Compound 2, or Compound 3.

Abstract: A method for data exchange and charging is provided. An implantable medical device is monitored and charging of the implantable medical device is initiated by providing charge parameters to a bedside monitor. Communication is initiated between a puck associated with the bedside monitor and implantable medical device. The implantable medical device is charged using the charge parameters. Simultaneously with the charging, transfer of data between the implantable medical device and the bedside monitor is initiated.

Abstract: Provided herein are methods of using 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, in combination with a second active agent for treating, preventing or managing multiple myeloma. The second active agent is one or more of a BTK inhibitor, an mTOR inhibitor, a PIM inhibitor, an IGF-1R inhibitor, an MEK inhibitor, an XPO1 inhibitor, a DOT1L inhibitor, an EZH2 inhibitor, a JAK2 inhibitor, a BRD4 inhibitor, a PLK1 inhibitor, an NEK2 inhibitor, an AURKB inhibitor, a BIRC5 inhibitor, a BET inhibitor, or a DNA methyltransferase inhibitor.

Abstract: Systems and methods obtain a database query, modify the database query into a modified database query incorporating a privacy mechanism configured for randomizing an attribute value of data in an answer to the modified database query, and output the modified database query. In some embodiments, the modified database query is forwarded to a database.

Abstract: Methods of controlling lockout of a switching or isolating component of an electrical grid are provided. A method of controlling lockout of a switching or isolating component includes, responsive to a plurality of trips occurring at the switching or isolating component during a predetermined time window, incrementing, by the switching or isolating component, a plurality of counters, respectively, and determining whether a number of the trips meets or exceeds a predetermined threshold. Moreover, the method includes, responsive to meeting or exceeding the predetermined threshold, driving the switching or isolating component to lockout. Related switching or isolating components are also provided.

Abstract: The present technology relates to adjustable shunting systems and methods. In some embodiments, the present technology includes an adjustable shunting system that includes a drainage element having an inflow portion configured for placement within a patient. The system can also include a flow control assembly having a gating element operably coupled to the outflow portion of the drainage element. The flow control assembly can further include a first actuation element and a second actuation element coupled to the gating element. The first and second actuation elements can be configured to selectively move the gating element relative to the outflow portion to control an amount of fluid flow therethrough. The first and second actuation elements can each extend less than entirely around a perimeter of the drainage element.

Abstract: A system may include a plurality of processors and a coprocessor. A plurality of coprocessor context priority registers corresponding to a plurality of contexts supported by the coprocessor may be included. The plurality of processors may use the plurality of contexts, and may program the coprocessor context priority register corresponding to a context with a value specifying a priority of the context relative to other contexts. An arbiter may arbitrate among instructions issued by the plurality of processors based on the priorities in the plurality of coprocessor context priority registers. In one embodiment, real-time threads may be assigned higher priorities than bulk processing tasks, improving bandwidth allocated to the real-time threads as compared to the bulk tasks.

Abstract: The present technology is directed to implantable medical devices for draining fluid from a first body region to a second body region. Some embodiments of the present technology provide adjustable devices that are selectively titratable to provide various levels of therapy. For example, the adjustable devices can have a drainage element with a lumen extending therethrough, a flow control element, and an actuation assembly. The actuation assembly can drive movement of the flow control element to change a dimension of and/or a flow resistance through the lumen, thereby increasing or decreasing the relative drainage rate of aqueous from an eye. In some embodiments, the actuation assembly and the flow control element together operate as a ratchet mechanism that can selectively move the flow control element between a plurality of positions and lock the device in a desired configuration until further actuation of the actuation assembly.

Abstract: The present disclosure relates to crystalline forms of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one hemihydrate (Compound 1) and/or tautomers thereof, wherein Compound 1 has the structure: (I)·0.5H2O; processes for preparing crystalline forms of Compound 1 and/or tautomers thereof; pharmaceutical compositions comprising the crystalline forms; methods of inhibiting a cell division cycle 7 in a mammal comprising administering the crystalline forms; and methods of treating a cell division cycle 7 mediated cancer in a mammal comprising administering the crystalline forms or a pharmaceutical composition comprising the crystalline forms.

Abstract: In an illustrative example, one or more coating formulations may be used and may have characteristics useful in different situations. During evaluations, a plurality of coating formulations comprising epoxy resins and diamine hardeners were prepared and evaluated with regards to impact ice adhesion strength and durability. Alone, such coating formulations provided a significantly reduced impact ice adhesion strength as compared to uncoated aluminum and/or stainless steel surfaces. However, a durability of the coatings, when applied to aluminum or stainless steel surfaces, was insufficient to be considered for use on external aircraft surfaces. By including nano-sized and/or micro-sized particles as additives to the coating formulations, resulted in improved durability without significantly reducing ice adhesion performance of the resin base.

Abstract: A cache may include multiple request handling pipes, each of which may further include multiple request buffers, for storing device requests from one or more processors to one or more devices. Some of the device requests may require to be sent to the devices according to an order. For a given one of such device requests, the cache may select a request handling pipe, based on an address indicated by the device request, and select a request buffer, based on the available entries of the request buffers of the selected request handling pipe, to store the device request. The cache may further use a first-level and a second-level token stores to track and maintain the device requests in order when transmitting the device requests to the devices.