Patents by Inventor A. Loomis

A. Loomis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Epidermal growth factor receptor antagonists and methods of use
    Publication number: 20060014690
    Abstract: The present invention features epidermal growth factor receptor (EGFR) antagonists. These EGFR antagonists are polypeptide variants of ligands of EGFR. The EGFR ligand polypeptide variants of the invention possess EGFR antagonistic properties and can inhibit at least one EGFR-mediated biological activity such as inhibition of the receptor's kinase activation activity and subsequently, cell proliferation. Such polypeptide variants, and nucleic acids encoding these polypeptide variants can be used therapeutically in situations in which inhibition of EGFR activity is indicated.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 19, 2006
    Inventors: Jeffrey Bishop, A. Loomis, Daniel Monticello, Philip Pienkos
  • Epidermal growth factor agonists and methods of use
    Publication number: 20050032162
    Abstract: The present invention features polypeptides that have at least 90% amino acid identity to wild-type epidermal growth factor, and also have epidermal growth factor biological activity that is greater than the biological activity of wild-type epidermal growth factor.
    Type: Application
    Filed: April 8, 2004
    Publication date: February 10, 2005
    Inventors: Wayne Coco, Philip Pienkos, A. Loomis