Abstract: A vehicle system is provided for correcting in real-time a camera-based estimated position of a road object. The system includes a camera for generating an image input signal including image sensor data associated with the road object. The system further includes one or more input devices for generating a vehicle input signal including vehicle sensor data associated with a position, a speed, and a heading of the vehicle. The system further includes a computer, which includes one or more processors and a non-transitory computer readable medium (CRM) storing instructions. The processor is programmed to match the image sensor data and the vehicle sensor data to one another based on a common time of collection. The processor is further programmed to determine an error model and a deviation of a current camera-based position from a predicted position. The processor is further programmed to update the error model based on the deviation.

Abstract: Adapter assemblies for connecting an endoscope to a robotic surgical system include a proximal housing, a distal housing, and a drive assembly. The distal housing is rotatable relative to the proximal housing via the drive assembly. A surgical assembly for interconnecting an endoscope and a surgical robotic arm includes a surgical instrument holder and an adapter assembly configured for receipt within the surgical instrument holder.

Abstract: The present invention relates to an inserter for an intrauterine system comprising a handle (3), and an insertion tube (6) having a first end and a second end, and being arranged in connection with the handle. The inserter is characterized in that the first end of the insertion tube (6) comprises at least one frame slot for receiving a frame of the intrauterine system. The invention also relates to a kit comprising an inserter according to the present invention and an intrauterine system, wherein the intrauterine system (1) comprises a therapeutic component (1b) and a continuous, closed frame (1a), the therapeutic component (1b) being connected to the frame (1a) at least one point, and therapeutic component (1b) of the intrauterine system (1) is at least mainly arranged inside the first end of the insertion tube (6) and the frame (1a) of the intrauterine system (1) is at least mainly arranged outside the first end of the insertion tube (6).

Abstract: A device includes a dielectric layer having a first surface and a second surface. The device also includes a first set of high-aspect ratio electroplated structures disposed on the first surface of the dielectric layer and a second set of high-aspect ratio electroplated structures disposed on the second surface of the dielectric layer opposite the first set of high-aspect ratio electroplated structures.

Abstract: A surgical assembly, a stabilisation plate and methods. The surgical assembly comprises includes a jig having a body with a tissue-engaging surface shaped to be received by tissue to be re-orientated by a correction factor. The body defines a plurality of alignment apertures orientated to be parallel with respect to each other on application of said correction factor.

Abstract: The present invention relates to compounds of formula (I) wherein Q is selected from O or S; R1 is a non-aromatic heterocyclic group comprising at least one ring nitrogen atom, wherein R1 is attached to the sulfur atom of the sulfonylurea group by a ring carbon atom, and wherein R1 may optionally be substituted; and R2 is a cyclic group substituted at the ?-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.

Abstract: Boots with fit adjustment systems that are configured to selectively adjust a fit of the boot on the wearer's foot by engaging the foot with more force and/or across a greater surface area relative to a pull-on boot that lacks the fit adjustment system. The fit adjustment system may adjust the fit of the boot without adjusting the external dimensions of the boot. The fit adjustment system includes an instep pad that is positioned interior of the external surface of the upper within an instep region of the boot, a lace that is coupled to the instep pad, and a lace adjustment mechanism. The lace adjustment mechanism includes a lace lock that selectively defines an adjustment length of the lace. Actuating the lace adjustment mechanism to reduce the adjustment length exerts a tightening force on the instep pad and draws the instep pad toward a heel region of the boot.

Abstract: A system for flushing a lumen of a medical device to remove air, comprising: a first fluid delivery device adapted to provide a pulsatile flow of a flushing gas from a pressurised source of the flushing gas; a second fluid delivery device adapted to provide a pulsatile flow of a flushing liquid from a source of the flushing liquid; and, at least one fluid coupling for connecting the first fluid delivery device and the second fluid delivery device to the lumen of the medical device.

Abstract: Various embodiments include cementitious compositions with low levels of embodied greenhouse gas emissions, in particular carbon dioxide, as a result of its production and/or use compared to conventional cementitious materials, such as portland cement. Various embodiments include any cementitious material or materials with low embodied carbon, as well as any material produced using this cement.

Abstract: The present disclosure relates to a formulation for a wide variety of poorly soluble drugs to improve bioavailability using a solid self-emulsifying drug delivery system. Compositions of the present disclosure can be used for improved delivery of hydrophobic or lipophilic pharmaceutical active ingredients, such as drugs, nutritional agents, cosmeceuticals, and diagnostic agents.

Abstract: A process for the microfluidic electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds comprising the steps of pumping a solution comprising a compound of Formula I into a microfluidic electrochemical reactor in the presence of a base, one of a halide or pseudohalide salt (MY), and a mediator; applying an electrical current through the microfluidic electrochemical reactor; and performing oxidative addition to create a geminal dipseudohalide or halide-pseudohalide compound of the general Formula II

Abstract: The present invention relates to sulfonylureas and sulfonylthioureas comprising a monocyclic imidazolyl group of formula (I): wherein Q is selected from O or S, R1 is an imidazolyl group, wherein the imidazolyl group is unsubstituted or substituted with one or more monovalent substituents, and R2 is a cyclic group substituted at the ?-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.

Abstract: A system for risk-based multi-factor authentication having a multi-dimensional time series data server configured to monitor and record a network's traffic data and to serve the traffic data to other modules and a directed computation graph module configured to receive network traffic data from the multi-dimensional time series data server, determine a network traffic baseline from the network traffic data, and determine a verification score needed before granting access based at least in part by the network traffic baseline. A plurality of verification methods build up a user's verification score to required level to gain access.

Abstract: The present invention relates to sulfonylureas and sulfonylthioureas of formula (I) comprising a 5-membered heteroaryl ring attached to the sulfonyl group, wherein the heteroaryl ring is di-substituted at the 3- and 4-positions relative to the point of attachment of the sulfonyl group, and wherein the group attached to the terminal nitrogen atom of the urea group is either a 1,2,3,5,6,7-hexahydro-s-indacen-4-yl group substituted at the 8-position, or a heteroaryl group substituted at the alpha and alpha? positions. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.

Abstract: Methods and systems that allow a recipient to electronically receive documents and accept service of process include receiving personally identifiable information about the recipient, generating a retrieval code specific to the recipient and/or the documents, and causing the retrieval code to be displayed on a page or device for delivery to the recipient. Later, the methods and systems receive user input including the retrieval code, verify that the user is the recipient, provide the recipient access to the electronic documents, and offer the recipient electronic delivery of the electronic documents. If the recipient agrees to the offer of electronic delivery, the methods and systems cause the electronic documents to be electronically delivered to the recipient; and after they deliver the documents in full, they present an acceptance document acknowledging and accepting the service of the electronic documents upon the recipient, and ask the recipient to execute it.

Abstract: A verification operating system (VOS) is an intermediary operating system that verifies data of a primary operating system before the primary operating system controls of the computing device. When the computing device is initialized, initial boot processes load the VOS instead of the primary operating system. The VOS performs verification processes on data storing the primary operating system to verify that the primary operating system has not been manipulated or corrupted before passing control of the computing device to the primary operating system. A VOS also may be used to verify an operating system used by a virtual machine (VM). The VOS verifies data storing a VM operating system to be used for requested VMs. If the VOS verifies that the VM OS data is accurate, the VOS provides the VM OS data to a hypervisor for use in a VM.

Abstract: A verification operating system (VOS) is an intermediary operating system that verifies data of a primary operating system before the primary operating system controls of the computing device. When the computing device is initialized, initial boot processes load the VOS instead of the primary operating system. The VOS performs verification processes on data storing the primary operating system to verify that the primary operating system has not been manipulated or corrupted before passing control of the computing device to the primary operating system. A VOS also may be used to verify an operating system used by a virtual machine (VM). The VOS verifies data storing a VM operating system to be used for requested VMs. If the VOS verifies that the VM OS data is accurate, the VOS provides the VM OS data to a hypervisor for use in a VM.

Abstract: A surgical instrument holder includes a carriage and a drive coupler. The carriage is configured for movable engagement to a surgical robotic arm. The drive coupler includes an outer member and a first gear rotatably disposed therein. The outer member extends from the carriage and defines a lateral slot configured for lateral receipt of a surgical instrument. The first gear defines a lateral slot and is rotatable within the outer member to a first position, in which the lateral slot of the first gear is in alignment with the lateral slot of the outer member such that a surgical instrument is receivable within the drive coupler through the lateral slots of the outer member and the first gear.

Abstract: A device receives, by way of a policy enforcement application, based on input by a user, a request to generate a resource. Responsively, the device generates a user interface comprising a plurality of blueprints for creating the resource by generating a set of signals by extracting data from a profile of the user, inputting the set of signals into a supervised machine learning model, and receiving, as output from the supervised machine learning model, a probability for each given blueprint of the plurality of blueprints that the user will access the given blueprint. The device assigns ranks to each given blueprint of the plurality of blueprints based on their corresponding probabilities and orders the plurality of blueprints based on the ranks. The device generates for display the user interface, each blueprint comprising a selectable option that, when selected, leads to fields for configuring the resource.