Abstract: Embodiments of the present invention provide a system for implementing authentication control protocols via components of entity device. In particular, the system may be configured to determine initiation of a resource interaction by a user at an entity device, control one or more components of the entity device to cause the entity device to capture a real-time image of the user, compare the real-time image captured via the entity device with an updated enhanced user image stored in a data file of the user, in response to comparing the real-time image with the updated enhanced user image, determine if the real-time image matches the updated enhanced user image, and implement one or more authentication control protocols based on determining if the real-time image matches the updated enhanced user image.

Abstract: Embodiments of the present invention provide a system for identifying and redirecting incoming unauthorized data access requests. The system is configured for continuously monitoring one or more incoming data access requests from one or more sources, identifying that a data access request of the one or more incoming data access requests is an unauthorized request, redirecting the data access request to a controlled environment, performing one or more actions in the controlled environment to capture one or more interactions associated with the data access request within the controlled environment, and automatically generating one or more controls to secure a real-time environment based on the one or more interactions captured within the controlled environment.

Abstract: Systems and methods are described that generate a first virtual space corresponding to a first multi-dimensional image set, where the first multi-dimensional image set includes one or more images generated based on receiving first imaging signals. The systems and method store pose information of one or more markers in association with a second virtual space, where the second virtual space corresponds to a second multi-dimensional image set including one or more ultrasound images generated based on receiving second imaging signals. The systems and method generate an image-based surgical plan in association with the first virtual space based on the pose information of the one or more markers. In some cases, the systems and method translate the pose information of the one or more markers to the first virtual space, and generating the image-based surgical plan is based on the translation of the pose information to the first virtual space.

Abstract: Various embodiments of the present disclosure disclose mitigating internal and external vibrational disturbances in opto-fluidic instrument. In various embodiments, the resonance frequency ranges and/or the vibrational frequency ranges of various modules and components of the opto-fluidic instrument may be selected to avoid resonances from occurring in the opto-fluidic instrument, thereby mitigating vibrations from internal and external sources that may distort the imaging of samples in the opto-fluidic instrument.

Abstract: Disclosed herein are methods and systems for automatically validating evidence of traffic violations. One instance of a method comprises receiving an evidence package comprising video frames showing a vehicle involved in a potential traffic violation. The video frames can be input into one or more deep learning models to obtain a plurality of classification results. The method can further comprise generating a score based in part on the classification results and evaluating the score against one or more thresholds to determine whether the evidence package is automatically approved, is automatically rejected, or requires further review.

Abstract: A method of impedance flow cytometry comprises: flowing a fluid along a flow channel; applying electrical signals to current paths through the fluid, the current paths comprising at least first and second current paths, and further first and second current paths, wherein the electrical signals applied to the first and further first current paths have a frequency, magnitude and phase, and the electrical signals applied to the second and further second current paths have substantially equal frequency and magnitude and opposite phase to the electrical signals applied to the first and first further current path; detecting current flow in the current paths; producing a first summed signal representing the sum of the current flows detected in the current paths, and a second summed signal representing the sum of the current flows detected in the further current paths; and obtaining a differential signal representing the difference between the summed signals.

Abstract: A system and method for analyzing and improving the performance of a body motion, which requires receiving, by a CPU, sensor data from sensors worn by a user; storing the transmitted sensor data in a data buffer; recognizing that a motion gesture occurred based on a signature of acceleration data in the buffered sensor data, extracting from the data buffer sensor data from a predetermined time window around the moment when the motion gesture occurred; automatically generating a regime file customized for the user based on the extracted sensor data, and generating in real-time a user interface displaying a representation corresponding to the motion indicated by the sensor data, wherein the CPU determines the signature of acceleration data by matching the buffered sensor data with stored motion signatures, wherein the regime file is automatically generated based on diagnostic parameters obtained from the sensor data associated with a motion activity category.

Abstract: A process for the preparation of polyfluoroalkylamines wherein polyfluoroalkylalcohols are reacted with an imide in the presence of SO2F2 and an acid scavenger in a first step and the compound obtained is then reacted with an acid, base or hydrazine in a second step.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.

Abstract: A garment may include a body having a channel and a belt loop extending along and at least partially recessed within the channel.

Abstract: Methods for identifying patients susceptible to treatment with checkpoint inhibitors are provided herein. Also provided are reagents for analyzing T cell responses for understanding resistance to checkpoint inhibitor therapy and understanding therapeutics for overcoming that resistance. Therapeutic strategies, for instance, for treating cancer, are also provided.

Abstract: Provided herein are compounds of formula (1): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein X1, X2, Ry, Rz, R1, R2, R3, and R4 are as defined herein. Also provided herein is a pharmaceutically acceptable composition comprising a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided herein are methods of using a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, to treat various diseases, disorders, and conditions responsive to the modulation of the contractility of the skeletal sarcomere.

Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic—cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

Abstract: A surgical stapling system comprising an actuator system operable to generate independent motions and a stapling end effector responsive to the independent motions generated by the actuator system is disclosed. The stapling end effector comprises a staple cartridge jaw comprising a plurality of staples removably stored therein, an anvil jaw, and a firing member. The firing member comprises an anvil-engaging portion and a cartridge jaw-engaging portion configured to engage the staple cartridge jaw.

Abstract: A coffee puck removal device (10) to remove a coffee puck (24) from a portafilter (20) is disclosed herein. The coffee puck removal device (10) has an open compartment (22) containing the coffee puck (24), the coffee puck (24) having an exposed major outer face (26) and a major inner face (28) when the coffee puck (24) is located in the open compartment (22). The device (10) includes: a body (12) having a rim (14) surrounding an aperture (16), with the rim (14) being configured to engage the portafilter (20), with the open compartment (22) facing the body (12) to inhibit air passing between the portafilter (20) and the rim (14); and a vacuum source (30) to remove air from the aperture (16) so that air pressure applied to the major inner face (28) is greater than air pressure applied to the exposed major outer face (26) so that the coffee puck (24) is removed from the portafilter (20).

Abstract: An apparatus for monitoring blood oxygen saturation of a subject is provided. The apparatus includes a unit configured for wearing on the subject's upper arm, the unit comprising first and second light sources configured to emit light of first and second wavelengths and a photodetector configured to detect light of the first and second wavelengths, where the light sources are arranged to direct light into the upper arm and the photodetector is arranged to detect light reflected from within the upper arm.

Abstract: The present invention relates, in various embodiments, to prediction of human subject states (e.g. physiological and/or psychological and/or neurological state) via a hybrid approach, which includes elements of AI-based classification and objective physiological analysis (such as blepharometric analysis). Embodiments are described by reference to applications in driver alertness monitoring. However, it will be appreciated that the technology is not limited as such, and has application in a broader range of context. For example, the technology is applicable to prediction of physiological states other than alertness level, and to implementation environments other than driver monitoring.

Abstract: The present inventions relate to a breeding system for the production of polyploid potato seeds, plants, or plant parts where cycles of meiosis, syngamy, and selection are used for interpopulation improvement of progenitor lines, and sexual polyploidization occurs during hybrid production by inducing clonal gamete formation in the parents that are to be crossed. Reciprocal recurrent selection can be used to inform selection of candidate potato lines that are either advanced to a gene editing or genetic modification system or crossed and selected to induce clonal gamete formation by arresting meiotic recombination and chromosome reduction. Crosses of parent plants bearing clonal gametes are planned and executed based upon predicted heterotic performance at the polyploid level. The final product is a homogeneous population of hybrid polyploid potato seed, or derivative thereof, bearing both parents' complete nuclear genomes. In some instances, the method is used to generate seedless plants.

Abstract: The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for treating diseases, such as cancer, autoimmune disorders, and inflammatory disorders.

Abstract: The present inventions relate to a breeding system for the production of polyploid maize seeds, maize plants, or maize plant parts where cycles of meiosis, syngamy, and selection are used for interpopulation improvement of progenitor lines, and sexual polyploidization occurs during hybrid production by inducing clonal gamete formation in the parents that are to be crossed. Reciprocal recurrent selection can be used to inform selection of candidate maize lines that are either advanced to a gene editing or genetic modification system or crossed and selected to induce clonal gamete formation by arresting meiotic recombination and chromosome reduction. Crosses of parent maize plants bearing clonal gametes are planned and executed based upon predicted heterotic performance at the polyploid level. The final product is a homogeneous population of hybrid polyploid maize seed, or derivative thereof, bearing both parents' complete nuclear genomes.