Abstract: Wound closure methods and apparatus are provided which utilize blood fluid by activating the clotting cascade of blood fluid outside the body within a substantially enclosed sterile container then introducing the blood fluid to the wound site to complete clotting. Methods and apparatus for providing ways of inhibiting anti-coagulating agents and slowing fibrin clot degradation are also disclosed. Kits for practicing the invention singularly or in combination with and/or associated with preferred procedures are also disclosed. The present invention provides improved methods of creating hemostasis or control of bleeding at the site of wounds, particularly wounds created in arteries during procedures employing percutaneous access. The invention preferably includes the steps of acquiring an aliquot of a patient's blood, i.e.

Abstract: A thermosetting composition comprising a co-reactable solid, particulate mixture of (a) capped polyisocyanate crosslinking agent, e.g., a trimer of 1-isocyanato-3,3,5 -trimethyl-5-isocyanatomethylcyclohexane capped with e-caprolactam or 1H-2,5-dimethyl pyrazole, and (b) hydroxy functional polymer, is described. The hydroxy functional polymer is prepared by atom transfer radical polymerization and has well defined polymer chain architecture and polydispersity index of less than 2.5. The thermosetting compositions of the present invention have utility as powder coatings compositions.

Abstract: A processor including a register, an execution unit, a temporary result buffer, and a commit function circuit. The register includes at least one register bit and may include one or more sticky bits. The execution unit is suitable for executing a set of computer instructions. The temporary result buffer is configured to receive, from the execution unit, register bit modification information provided by the instructions. The temporary result buffer is suitable for storing the modification information in set/clear pairs of bits corresponding to respective register bits of the register. The commit function circuit is configured to receive the set/clear pairs of bits from the temporary result buffer when the instruction is committed. The commit function circuit is suitable for generating an updated bit in response to receiving the set/clear pairs of bits. The updated bit is then committed to the corresponding register bit of the register.

Abstract: A work machine is provided and adapted for use in paving operations. The work machine has a conveying system for moving paving material from a first end portion to a predetermined distance beyond a second end portion. A receiving portion is included on the second end portion and is adapted to receive a plurality of operational attachments. The plurality of attachments transforms the work machine into three distinct machines that perform different paving operations.

Abstract: A system is disclosed for facilitating operation of a peripheral bus, such as a PCI bus, that operates at multiple clock speeds. The system includes an expansion slot controller that identifies the number of peripheral devices that have been installed in the expansion slots, and further determines whether these devices support high speed operation. The expansion slots transmit a signal indicating the presence of a peripheral device in the slot, and also transmit a signal indicating whether the device is operable at the higher clock frequency. Once the expansion slot controller determines this information, it decides whether operation at the higher frequency is supported by the peripheral devices and by the bus bridge. The expansion slot controller informs each peripheral device of what the operating frequency will be, and transmits a signal to the PCI bus bridge indicating if high frequency operation will be supported.

Abstract: A method of producing refastenable side seams in an absorbent garment results in an absorbent garment that is adapted to easy application and removal. The refastenable side seams can be produced in either a cross direction or a machine direction. Each of the refastenable side seams is a dual side seam that includes a standing butt seam formed between a front lap seam and a back lap seam. The resulting garment can be opened and closed on either a front side of the garment or a back side of the garment.

Abstract: A system and method for managing the installation of equipment, machines or systems. The system comprises tools that are operable to develop and manage an installation plan. The installation plan provides a timetable for the performance of installation tasks. The installation plan may be developed and managed using an information system that is accessible via a network or using a portable remote unit. The method comprises using the tools to develop and manage the installation plan.

Abstract: Devices, systems and methods are provided for piercing the skin, accessing and collecting physiological sample therein, and measuring a characteristic, e.g., an analyte concentration, of the sampled physiological sample. The subject devices are in the form of a test strip which include a biosensor and at least one skin-piercing element which is a planar extension of a portion of the biosensor. At least one fluid pathway resides within a portion of the biosensor and within the skin-piercing element. The skin-piercing element has a space-defining configuration therein which acts as a sample fluid pooling area upon penetration into the skin. Systems are provided which include one or more test strip devices and a meter for making analyte concentration measurements. Methods for using the devices and systems are also provided.

Abstract: Improved drying, binder evaporation, and sintering processes which may be used in conjunction with specialized sintering tools to provide for the geometrically stable sintering of large, complex, metal injection molded preform parts or flowbodies. The improved process includes a three-stage drying process, a single stage binder evaporation process, and a two-stage sintering process.

Abstract: The present invention provides a septal defect closure device (10) having a first occluding disk (30) having a first flexible membrane (32) attached to a first frame (34) and a second occluding disk (20) having a second flexible membrane (22) attached to a separate second frame (24). The first frame has at least two outwardly extending loops joined to one another by flexible joints. These loops are attached to the first membrane to define taut fabric petals when the first disk is in a deployed configuration. A central portion of the first membrane is joined to the central portion of the second membrane via a joining segment, which may comprise a conjoint disk. The flexible joints of the first frame are received within the joining segment. This septal defect closure device provides enhanced retrievability.

Abstract: Three or more diaphragm pumps (12,14,16) are interconnected to sequentially receive an activation fluid from corresponding piston and cylinder pumps (18,20,22) synchronized by a control mechanism (24) which includes a distributor plate (42) with directive shallow slots (80,82,84) for conduiting activation fluid to a porting plate (44) and via openings (60,62,64) to the piston and cylinder pumps (18,20,22).

Abstract: This invention is directed to methods for treating aneurysms wherein the aneurysmal sac is filled with a non-particulate agent or plurality of such agents and/or with a fluid composition which solidifies in situ. Filling of the aneurysmal sac employs sufficient amount of the non-particulate agent or plurality of such agents and/or the fluid composition to inhibit blood flow into the aneurysm sac. In addition, the methods of this invention also provide for non-endogenous isolation of the parent artery proximal and distal to the aneurysmal sac from systemic blood flow of the treated mammal. The combination of these features provides for treatment of the aneurysmal sac while, at the same time, inhibiting aneurysm formation and/or regrowth in the diseased portions of the arterial wall proximal and distal to the treated aneurysm.

Abstract: A safety line system includes support assemblies which clamp to respective reinforcement bars protruding upward beyond the top surface of a concrete beam. The support assemblies include stanchion assemblies having respective posts that may be selectively pivoted relative to the beam. The support assemblies also preferably include end anchor assemblies that are connected to respective stanchion assemblies by respective chains.

Abstract: A system and method for modeling the power consumed by a logic cell in a computer controlled power estimation process estimating the power consumed for an integrated circuit represented by logic cells and connections between cells. The present invention models power consumption within a logic cell associated with a particular designated pin (output, internal, or bidirectional) based on which input (or internal or bidirectional) pin transitioned causing the designated pin to transition. This is referred to as path dependent power modeling. A different power consumption value can be provided for each different modeled transition. The logic cells and the power consumption model for them are stored in a logic cell “library” within the computer system. Path dependent power modeling of the present invention allows library designers to specify a different set of power values depending on which pin transition (e.g., input pin) caused the designated pin to transition.

Abstract: Methods and apparatus are disclosed for correcting spectral measurements, such as are obtained by a spectrophotometer for measuring color. A single matrix is used that operates on a raw measurement vector (spectrum) to obtain a corrected spectrum. The matrix may embody a transform that minimizes the difference between the corrected spectra and a set of reference spectra. The difference may be characterized by a set of basis function weighting vectors which are then used to build the correction matrix. Correction of high resolution spectra (very long measurement vectors) is thereby allowed, without the large number of measurements that would normally be required. The reference spectra can be calibration data, or measurements made by another instrument which is desired to be simulated.

Abstract: A transmission for transmitting rotary power in forward and reverse directions from a programmable source of input motion such as an electric motor uses individually rotatable coaxially mounted lock plates each having a pawl receiving socket therein providing access to an arcuate slot of selected angular length permits engagement and disengagement of the transmission only when input torque is applied thereto in forward and reverse directions to rotate the transmission input gear through pre-defined angles. The pawl is part of a frictionally driven shift arm on which a driven shift gear is also mounted whereby the driven shift gear is pivotally moved into and out of engagement with the output gear or gears of the transmission when the pawl is pivotally moved out of or into the sockets in the lock plates.

Abstract: The present invention relates to a novel cardiac-specific transcription factor, myocardin. This molecule modulates the development and differentiation of cardiomyocytes and is a potent inhibitor of cell growth. Methods to exploit these observations are provided and include respecifiying non-cardiac cells into cardiac cells, stimulating cardiac tissue regeneration, and methods for treating cardiomyopathies, myocardial infarction.

Abstract: A hydraulic washer or spacer is used to reduce friction between a planet gear and the planet carrier. The washer has a top side and a bottom side, an inner diameter and an outer diameter. A mating profile extends from the inner diameter to the outer diameter along the bottom side adjacent the planet gear. The top side has a pumping land, pressure pocket, and bearing surface arranged from the inner diameter to the outer diameter respectively. The pumping land extends from the inner diameter outward radially to the pressure pocket. The pressure pocket is recessed relative to the pumping land and extends from the pumping land outward radially to a containment edge. The containment edge is raised relative to the pressure pocket and pumping land. Extending from the containment edge to the outer diameter is a bearing surface that is also raised relative to the pressure pocket and pumping land. As the washer rotates, the surrounding fluid is subject to centrifugal forces.

Abstract: An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. Obturator assemblies and infusion catheter assemblies are provided to be used with the evacuation sheath assembly. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped and the stenosis is treated.

Abstract: An optical sensor generates blood pressure data by obtaining two dimensional images of the surface of the patient's body, such as in the vicinity of the radial artery in the wrist area. Blood flow in the patient causes light to be reflected off a flexible reflective surface applied against the patient with a hold down pressure, and the scattering of light is sensed with a two-dimensional array of photo-detectors. The output of the photo-detectors during systolic and diastolic events is calibrated against known blood pressure measurements taken with a conventional air-cuff sphygmomanometer. Linear calibration relationships between output signal and blood pressure are obtained during calibration for some set of the photo-detectors. When blood pressure data is obtained from the patient, the linear calibration relationship between output signals and blood pressure is applied to the output signals from the set of photo-detectors, resulting in blood pressure data.