Abstract: An electric motor drive system in a vehicle comprises: a three-leg inverter for driving the electric motor in the vehicle and a fourth leg connected in parallel with the three-leg inverter. The fourth leg comprises a positive temperature coefficient resistor connected in series with a switch. The electric motor drive system further comprises a control unit configured to switch on the switch in the fourth leg for a period of time ts during a regenerative mode of the electric motor such that the PTC resistor is switched in a path of short circuit current flowing through any of the switch transistors in the three-leg inverter to reduce the peak short circuit current generated from the electric motor during the regenerative mode.

Abstract: A mandrel device (50) for manufacturing a hollow spar beam (30) for a segmented wind turbine blade (10) in a mould (100), the mandrel device comprising: a plurality of mandrel elements (52, 53, 54, 55, 56, 57, 58, 59) each comprising a substantially rigid material, and a plurality of attachment devices (60) configured for detachably attaching adjacent mandrel elements, wherein the mandrel device has an assembled configuration and a detached configuration, wherein: in the assembled configuration, the plurality of attachment devices is engaged so that the plurality of mandrel elements is detachably attached to each other, and the plurality of mandrel elements extends along a longitudinal axis of the mandrel device so that the mandrel device has a substantially box shaped cross-section that varies along the longitudinal axis, and in the detached configuration, the plurality of attachment devices is disengaged so that the plurality of mandrel elements is detached from each other, and the plurality of mandrel

Abstract: A method may include receiving, at a storage device, a command using a storage protocol, wherein the storage device is configured to execute a user program, and executing, at the storage device, a device program based on the command. The command may be a first command, and the method may further include receiving, at the storage device, using the storage protocol, a second command, and sending, from the storage device, using the storage protocol, information about the device program based on the second command. The method may further include sending, from the storage device, using the storage protocol, a list of device programs supported by the storage device based on the second command. The method may further include providing, by the storage device, output data from the device program. The providing may include sending, from the storage device, using the storage protocol, a log message.

Abstract: An example computer system for migration of information can include: one or more processors; and non-transitory computer-readable storage media encoding instructions which, when executed by the one or more processors, causes the computer system to create: a synchronization module programmed to migrate data from a source data store to a target data store, wherein the synchronization module is configured to control how much of the data is migrated; and a validation module programmed to validate the data between the source data store and the target data store.

Abstract: Systems and methods of identifying errors in RF cabling using system level distance to fault. A method of determining system level RF health in an RF deployment, the method including predicting an RF health of the deployment based on a known attribute of the deployment; receiving a distance to fault (DTF) measurement from the deployment, wherein receiving the DTF measurement includes: transmitting a test signal into a cable associated with the RF deployment; and receiving a return signal from the cable, the return signal including a reflection; comparing the predicted RF health to the received DTF measurement; and identifying mismatches between the predicted RF health and the received DTF measurement based on the comparing.

Abstract: The present invention includes methods of treating cancer in a patient, the method comprising the steps of: (a) providing or obtaining a sample from a patient; (b) determining at least one of a level or activity of at least one of: T follicular regulatory (TFR), ST2 Treg, highly suppressive Treg, activated Treg, or effector Treg cells in the sample; (c) comparing the at least one level or activity of the T cells in the sample to a level or activity of the T cells in a reference sample, respectively, for a specific tumor type or a healthy subject; and (d) if the patient has the at least one of the high level or activity of the T cells systemically as compared to the reference sample, then administering a cancer therapy to the patient that comprises a modified dosage or administration of a Phosphoinositide 3-kinase (PI3K) inhibitor.

Abstract: Improved techniques for secure access to cloud-based services via a gateway proxy. The improved techniques can efficiently manage remote access to cloud-based services by local processing agents in a secure manner using an intermediate authentication token issued by a gateway proxy to authorized local processing agents. The intermediate authentication token can be used to obtain authentication credentials of service providers that are needed to access the cloud-based services that are offered by service providers. In some embodiments, the authentication credentials of service providers need only be distributed to the gateway proxy and need not be distributed beyond the gateway proxy. The improved techniques are well suited for used with robotic process automation systems in which local processing agents, such as software agents, perform user tasks in an automated fashion.

Abstract: A system for measurement is provided. The system includes a first optical path configured to supply first light pulses with a first range of wavelengths; a second optical path configured to supply second light pulses with a second range of wavelengths shorter than the first range of wavelengths; an optical I/O unit configured to emit the first light pulses and the second light pulses to a target and acquire a light from the target to detect CARS light pluses from the target by a detector; and a first phase modulating unit configured to vary phase differences between the first light pulses and the second light pulses as the first light pulses and the second light pulses are emitted via the optical I/O unit.

Abstract: Systems and methods for identifying and extracting specific product usage patterns of potential customers and utilizing a machine learning evaluation model to predict the potential customers that are most likely to convert their subscriptions.

Abstract: Improved techniques for secure access to cloud-based services via a gateway proxy. The improved techniques can efficiently manage remote access to cloud-based services by local processing agents in a secure manner using an intermediate authentication token issued by a gateway proxy to authorized local processing agents. The intermediate authentication token can be used to obtain authentication credentials of service providers that are needed to access the cloud-based services that are offered by service providers. In some embodiments, the authentication credentials of service providers need only be distributed to the gateway proxy and need not be distributed beyond the gateway proxy. The improved techniques are well suited for used with robotic process automation systems in which local processing agents, such as software agents, perform user tasks in an automated fashion.

Abstract: A method for communicating with a device may include running, at a device, an operating system, communicating, using a first function of an interconnect, with the device, and communicating, using a second function of the interconnect, with the operating system. The operating system may include communication logic, and the communicating with the operating may include communicating with the communication logic. The communication logic may one or more terminal support drivers, and the communicating with the communication logic may include communicating with the one or more terminal support drivers using a terminal application. The terminal application may run on a host. The second function of the interconnect may be configured to operate with a controller. The communicating with the operating system may include communicating with the operating system based on a privilege information. The host may be a management controller.

Abstract: The present invention discloses a therapeutic composition comprising fusion protein with reduced heterogeneity in the glycosylation profile of the protein and methods thereof. More particularly the invention provides the composition with reduced heterogeneity in the glycosylation profile. By reducing heterogeneity, the resultant preparation is expected to exhibit superior, consistent results in terms of safety, purity and potency. The invention is of particular importance as it can form the part of the critical quality attributes (CQA) that help in ensuring batch-to-batch consistency and predicted shelf-life of complex protein molecules.

Abstract: Methods of treating viral diseases are disclosed herein. Certain methods include diagnostic methods that quantify levels of biological features associated with TFH or CD4-CTL cells. Certain methods include treatment methods that affect the number, functionality, activity, or expression of TFH or CD4-CTL cells or TREG cells.

Abstract: This disclosure relates to shaker adjustments based on sensor measurements for sensors positioned at different locations about the shaker. This disclosure explains techniques to adjust a shale shaker as would be used to separate particulates (cuttings and other solids) from drilling fluid (commonly referred to as “mud”) during a drilling operation. Empirical models have been formulated to provide for programming a controller to calculate run-time adjustments to the shaker to increase efficiency. The controller may control one or more shakers concurrently. Different techniques and measurement types may be used concurrently to achieve desired shaker inclination and maintain a proper beach location during operation. Sensors include accelerometers, proximity sensors, and other types of data acquisition devices that may be used to detect motion parameters of an operational (e.g., in-use and running) shaker.

Abstract: A storage device is disclosed. The storage device may include storage to store data, which may include a first storage of a first type and a second storage of a second type. The storage device may support a number of device streams, some of which associated with the first storage and some associated with the second storage. The storage device may also include a streaming capabilities analyzer that may inventory the streaming capabilities for the storage device. Finally, the storage device may include a transmitter to transmit the streaming capabilities of the storage device to a storage manager.

Abstract: The present invention includes engineered T cell receptor (TCR) proteins, nucleic acids, vectors, host cells, methods of treating cancer, and chimeric antigen receptor expressing T cell (CAR-T) comprising an alpha chain CDR3 having the amino acid sequence of SEQ ID NO: 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, or 23 and/or a beta chain CDR3 having the amino acid sequence of SEQ ID NO: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, or 24, wherein the TCR is specific for a KRAS G12>V mutation peptide, antigen-MHC binding portions, and full length portions of the same.

Abstract: Global transcriptional profiling of CTLs in tumors and adjacent non-tumor tissue from treatment-naïve patients with early stage lung cancer revealed molecular features associated with robustness of anti-tumor immune responses. Major differences in the transcriptional program of tumor-infiltrating CTLs were observed that are shared across tumor subtypes. Pathway analysis revealed enrichment of genes in cell cycle, T cell receptor (TCR) activation and co-stimulation pathways, indicating tumor-driven expansion of presumed tumor antigen-specific CTLs. Marked heterogeneity in the expression of molecules associated with TCR activation and immune checkpoints such as 4-1BB, PD1, TIM3, was also observed and their expression was positively correlated with the density of tumor-infiltrating CTLs.

Abstract: A programmable data storage device includes: a non-volatile memory; a storage controller configured to control the non-volatile memory; a network interface; and a field programmable gate array configured to: implement a blockchain algorithm; and store at least one block of a blockchain corresponding to the blockchain algorithm in the non-volatile memory via the storage controller; and a processor having memory coupled thereto, the memory having instructions stored thereon that, when executed by the processor, cause the processor to: send and receive one or more blocks of the blockchain via the network interface; and control the field programmable gate array to execute the blockchain algorithm on the one or more blocks of the blockchain.

Abstract: A method for communicating with a device may include running, at a device, an operating system, communicating, using a first function of an interconnect, with the device, and communicating, using a second function of the interconnect, with the operating system. The operating system may include communication logic, and the communicating with the operating may include communicating with the communication logic. The communication logic may one or more terminal support drivers, and the communicating with the communication logic may include communicating with the one or more terminal support drivers using a terminal application. The terminal application may run on a host. The second function of the interconnect may be configured to operate with a controller. The communicating with the operating system may include communicating with the operating system based on a privilege information. The host may be a management controller.

Abstract: A Solid State Drive (SSD) is disclosed. The SSD may include flash memory to store data. An SSD controller may manage reading and writing data to the flash memory. The SSD may include an automatic stream detection logic to select a stream identifier responsive to attributes of data. A garbage collection logic may select an erase block and program valid data in the erase block into a second block responsive to a stream ID determined the automatic stream detection logic. The stream ID may be determined after the garbage collection logic has selected the erase block for garbage collection.