Abstract: A system and method of performing a rebase action to image layers of a container. The method includes receiving a first indication that an image update of a first container is available. The first container includes a base layer and one or more first layers. The method includes updating, in response to receiving the first indication, the base layer based on the image update to create an updated base layer. The method includes rebasing, by a processing device using the updated base layer, the one or more first layers to create one or more rebased first layers. The method includes the storing the one or more rebased first layers in a repository to be reused to update a second container.

Abstract: The invention provides AML-specific methylation biomarkers (SP140, MCCC1, EHMT1 and MTSS1). In one embodiment, a biomarker is differentially methylated, specifically in AML.

Abstract: A method includes encoding a first message including first parameters for a first color transform that transforms a video signal into a first color-mapped video signal; encoding a second message including second parameters for a second color transform that transforms the video signal into a second color-mapped video signal; and encoding the video signal, the first message, and the second message in a video bitstream. A method includes decoding the video bitstream into the video signal, the first message including the first parameters, and the second message including the second parameters, and performing at least one of the following: displaying the video signal; transforming the video signal into the first color-mapped video signal by applying the first color transform and displaying the first color-mapped video signal; and transforming the video signal into the second color-mapped video signal by applying the second color transform and displaying the second color-mapped video signal.

Abstract: An elastic securing organ for fastening a horological component on a support element including an outer peripheral wall capable of being connected to said horological component and an inner peripheral wall defining a triangular-shaped opening wherein the support element is capable of being inserted, the elastic securing organ includes elastic arms each forming one side of the triangular opening and helping ensure the gripping of the support element in the opening, each arm including: at least one cut-out defined completely or partially along the body of said arm, an elastic contact zone with the support element, and elastic peripheral zones which extend between this contact zone and the ends of this elastic arm, the contact zone having a greater quantity of material than the quantity of material forming each of the peripheral zones thereof.

Abstract: Systems and methods are provided herein for improving connections between a heart pump such a left ventricular assist device (LVAD) and the heart and/or tubing such as a graft tube. An apical connector including a cylindrical housing and a ring support connected to the housing is described. The apical connector may include a sewing ring to be connected to the patient's heart and a spring positioned within the cylindrical housing to engage a portion of the pump and secure the apical connector to the pump. Alternatively, an apical connector may include an upper and lower housing with locks positioned in channels between the housings and may include a handle and a ring to cause the locks to engage a portion of the pump. A quick connect assembly is also described for efficiently connecting a graft tube to an outlet of a heart pump using a flange with through-holes and protrusions.

Abstract: A cochlear implant system is disclosed. The system includes an external unit configured to receive acoustical sound and process the acoustical sound into a coded audio signal, and an implantable unit configured to receive the coded audio signal. The system further comprises a pulse generating unit configured to generate a first electrical pulse of a first pulse duration and a second electrical pulse of a second pulse duration different from the first pulse duration based on the coded audio signal. The system still further comprises an electrode array including a plurality of electrodes, wherein at least one of the plurality of electrodes is configured to receive at least the first electrical pulse and the second electrical pulse, and a capacitor connected to the at least one of the plurality of electrodes.

Abstract: A swivel arrangement including high voltage electrical swivels concentrically arranged around a common axis, each swivel including: a first annular housing part and a second annular housing part together defining an internal annular volume; a first solid electrical conductor stationary with respect to the first annular housing part, and a second solid electrical conductor stationary with respect to the second annular housing part, wherein the first and second electrical conductors are arranged within the internal annular volume for making conductive sliding contact with each other, wherein the first annular housing part and second annular housing part are rotatable relative to each other around the common axis while the first and second electrical conductors are in sliding contact with each other; wherein the swivels are arranged concentrically around the common axis so that a plane normal to the axis intersects at least two, preferably three, of the electrical swivels.

Abstract: A surgical guide device can be attached to a patient's bone for assisting an open wedge osteotomy. This device includes two parts which are joined together by way of removable securing unit, namely: a proximal part, including a lower border defining at least one portion of the upper edge of a guide window, and a distal part having an upper edge defining at least one portion of the lower edge of the guide window. The proximal and distal parts are each provided with a plurality of through holes adapted for receiving members temporarily implantable in the bone and/or adapted to guide a drilling of holes in the bone. The arrangement of the through holes of the surgical guide device advantageously takes into account the planned open wedge osteotomy and anticipates the final position of the screw locations of the reported osteosynthesis plate for freezing the two bone fragments.

Abstract: An electronic device may have a display with pixels configured to display an image. The pixels may be overlapped by a cover layer. The display may have peripheral edges with curved cross-sectional profiles. An inactive area in the display may be formed along a peripheral edge of the display or may be surrounded by the pixels. Electrical components such as optical components may be located in the inactive area. An image transport layer may be formed from a coherent fiber bundle or Anderson localization material. The image transport layer may overlap the pixels, may have an opening that overlaps portions of the inactive area, may have an output surface that overlap portions of the inactive area, and/or may convey light associated with optical components in the electronic device.

Abstract: The present disclosure related to compounds that can be useful as inhibitors of PD-1, PD-L1 or the PD-1/PD-L1 interaction. Also disclosed herein are pharmaceutical compositions of that can include a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and uses of or methods of using a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for the treatment of PD-L1 related diseases including but not limited to liver diseases, cancer, hepatocellular carcinoma, viral diseases, or hepatitis B.

Abstract: Provided are organoiridium compounds that are useful as emitters in OLEDs. The compounds have Formula I L1L2Ir-L-Ir-L3L4, where: L is a bis-bidentate ligand including two or more aromatic rings; one of the two or more aromatic rings is bonded to the two Ir atoms at the same time; and each of L1, L2, L3, and L4 is independently a bidentate N-heterocyclic carbene ligand or a substituted or unsubstituted acetylacetonate ligand with L1, L2, L3, and L4 each being the same or different. Also provided are formulations including these organoiridium compounds. Further provided are OLEDs and related consumer products that utilize these organoiridium compounds.

Abstract: A method for designing one part of an electrostatic separating device of a mixture of different material granules, the method including providing a sorting performance value to be met by the device when at least one predefined mixture is introduced into the device to be sorted, optimizing a value of at least one parameter of the set of parameters relating to the device part by using an optimization technique, the optimization technique including the use of a sorting performance model of the device, and the optimization technique occurring under the constraint that the sorting performed by the device has the given sorting performance value.

Abstract: A supply system for an aircraft arranged between two dihydrogen tanks and an engine. The supply system includes a supply module that assures the flow of dihydrogen between the tanks and an outlet pipe and two heaters mounted in series on a main pipe connected to the engine. The supply system also includes a network of pipes and solenoid valves that, in the event of a problem in one of the components of the supply system, enable dihydrogen to be redirected so as to reach the engine. Also an aircraft with such a supply system.

Abstract: A marine vessel control system comprises a propulsion unit and a steering actuator for steering the propulsion unit. There is a shift actuator for shifting gears in the propulsion unit and a throttle actuator for increasing or decreasing throttle to the propulsion unit. There is an input device for providing user inputted steering commands to the steering actuator and for providing user inputted shift and throttle commands to the shift actuator and the throttle actuator. There is a sensor for detecting a global position and a heading direction of the marine vessel. A controller receives position and heading values of the marine vessel from the sensor. The controller compares the received position value to a pre-programmed position value to determine a position error difference. The controller also compares the received heading value to a pre-programmed heading value to determine a heading error difference.

Abstract: A system and method for processing user requests of a user device by a plurality of networked computing devices is provided. The method involves: (a) receiving a first user request by a first computing device; (b) determining whether the first computing device is optimally selected for processing the user requests; (c) if not optimally selected, selecting from among the networked computing devices an optimal device having an optimal response time; and (d) directing subsequent user requests from the user device to the optimal device. A system and method for maintaining a computing process executable by a computing device is provided. The method involves: (a) receiving by a maintenance device a status indication associated with the computing process; (b) determining one or more proposed actions associated with the status indication; (c) selecting a maintenance action from among the proposed actions; and (d) executing the maintenance action at the computing device.

Abstract: A suction gripper head includes at least one carrier and a soleplate for resting against an item to be lifted. The soleplate is arranged in the bottom portion of the carrier. The head comprises a foam body having a suction path arranged therein between the soleplate and an outlet orifice of the gripper head for connection to a suction block, the foam body thus acting on its own, over at least a portion of the path, to form the separation between air sucked through said path and the outside of the gripper head, such that the air that is being sucked comes directly into contact with the foam of the foam body.

Abstract: A docking system for intraocular surgery that is configured to simultaneously: (1) physically stabilize a position and an orientation of an eye during intraocular surgical procedures; (2) preserve an unobstructed path for optical instruments; (3) provide access to the eye that allows for tool movement; (4) maintain eyeball hydration and improve the scan quality of an imaging system, such as an OCT system or a surgical microscope and may maintain or control an intraocular pressure of the eye to a stable, desired level during surgical procedures.

Abstract: A retractable protection device for protecting a user's head against environmental elements, the device includes at least one hoop, at least two articulations of at least one hoop with a base, each articulation being attached to one end of at least one hoop, at least one articulation comprising a means for locking said hoop in a predefined position referred to as the “deployed position”. The device further includes at least partially closed base, configured to surround the user's nape at least partially, and a sheet of fabric attached to each hoop and the base to create a protection screen around the user's head in the deployed position, the fabric and hoops being circumscribed by the base in a position referred to as the “folded position” that minimizes the size of the device, between the user's nape and shoulders, freeing up the user's back.