Abstract: Disclosed is an improved approach for managing, tracking, and querying hierarchical data in layouts. According to some aspects, hierarchical grids are employed utilizing a scheme that organizes physical objects into a set of gradually refined grids that avoids the need to maintain duplicates while enhancing the desirable characteristics of existing schemes, including fast query times, fast data structure initialization and reduced memory footprint. Each grid-cell may be further partitioned into sub-containers to more efficiently provide space pruning during query operations. According to one approach, structures maintained to track existence of objects in a descendent hierarchy.

Abstract: Disclosed is an improved approach for managing, tracking, and querying hierarchical data in layouts. According to some aspects, hierarchical grids are employed utilizing a scheme that organizes physical objects into a set of gradually refined grids that avoids the need to maintain duplicates while enhancing the desirable characteristics of existing schemes, including fast query times, fast data structure initialization and reduced memory footprint. Each grid-cell may be further partitioned into sub-containers to more efficiently provide space pruning during query operations. According to one approach, structures maintained to track existence of objects in a descendent hierarchy.

Abstract: Disclosed are biologically active hetero pyrrole analogs such as imidazoles, thiazoles, oxazoles and pyrazoles capable of interacting with the CB1 and/or the CB2 cannabinoid receptors. One aspect discloses hetero pyrrole analogs acting as antagonists for the CB1 and/or the CB2 receptors. Another aspect discloses hetero pyrrole analogs having selectivity for the CB1 or CB2 cannabinoid receptor. Also disclosed are pharmaceutical preparations employing the disclosed analogs and methods of administering therapeutically effective amounts of the disclosed analogs to provide a physiological effect.

Abstract: Methods, apparatuses and computer program products are provided for facilitating the expedited dispensing of medications from an automated medication storage device. In this regard, a method may cooperate with the first device to facilitate the presentation of various displays that include features to reduce number of user interactions to dispense medications safely and effectively.

Abstract: The present invention relates to an active transdermal analyte detection system performing extraction and detection of body analytes comprising of a patch accepting at least one electrical input; a plurality of transducers configured for converting input electrical energy to different forms of energies for activating extraction procedure; a controller configured for providing the control signals, intensity, sequence, nature, and timing information for the different energies supplied to the said patch vide said transducers; and at least one layer/compartment configured for either collection of extracted fluids and/or delivering at least one reagent formulation that detects the body analyte on activation and a method for performing transdermal extraction and detection of body fluids using said electronic patch.

Abstract: A wireless station (A) is operated in a power-save mode, in which the station is alternately in power-ON and power-OFF states to reduce power consumption. Wireless station (A) computes at least some future time instances at which another wireless station (B) is expected to start transmitting control messages. Wireless station (A) is ensured to be in the power-ON state in corresponding time intervals encompassing durations of at least some of such future transmissions of control messages by wireless station (B), and is thereby enabled to receive the control messages. In an embodiment, the control messages correspond to group key message updates in which values of a decryption key are transmitted, wireless station (A) being a wireless client, wireless station (B) being an access point, with wireless stations (A) and (B) operating in a wireless network consistent with IEEE 802.11 specifications, and communication between wireless stations (A) and (B) being encrypted.

Abstract: The present invention relates to a system and method for routing a data from one or more mobile communication channel to one or more fixed communication channel in a resource efficient manner. The delinking router of the system communicates with the one or more mobile communication channel and with one or more fixed communication channel and transmits the request to a Base Transmitting Station (BTS) for routing the data from the mobile communication channel to the fixed communication channel. The delinking router also reduces energy and spectrum consumption of the mobile communication channel by turning off its radio frequency module after routing its data to the fixed communication channel.

Abstract: A storage area network (SAN)-attached storage system architecture is disclosed. The storage system provides strongly consistent distributed storage communication protocol semantics, such as SCSI target semantics. The system includes a mechanism for presenting a single distributed logical unit, comprising one or more logical sub-units, as a single logical unit of storage to a host system by associating each of the logical sub-units that make up the single distributed logical unit with a single host visible identifier that corresponds to the single distributed logical unit. The system further includes mechanisms to maintain consistent context information for each of the logical sub-units such that the logical sub-units are not visible to a host system as separate entities from the single distributed logical unit.

Abstract: Embodiments of the present invention disclose a method and device for selecting a sampling clock signal. The method includes: obtaining, by a logic chip, a data edge of a data signal and a clock edge of a clock signal, selecting a sampling edge according to the data edge and the clock edge, and sending a selecting signal corresponding to the sampling edge to a selector; and selecting, by the selector, a sampling clock signal according to the selecting signal. The technical solutions provided by the embodiments of the present invention can solve problems of poor system maintainability and high cost of operation and maintenance because a receiver device needs to select a sampling clock signal through manual configuration in the synchronous serial-port communication in the prior art.

Abstract: A system, method, and apparatus for generating a low noise bias current to improve jitter performance in a wide frequency range LC-based phase-locked loop (PLL) circuit for multi-speed clocking applications. A plurality of noise-reducing stages are coupled in series and disposed between a power supply and a voltage controlled oscillator (VCO) including: a first stage VCO regulator; and a second stage bias circuit having a plurality of PMOS transistors cascode-coupled to each other and optionally grouped into one or more parallel branches of cascode-coupled transistor pairs. Each branch can be automatically enabled by a calibration code based on the desired reference clock signal in order to provide a wide range of currents to the voltage controlled oscillator. The cascode coupled pair includes a bias transistor coupled in series with a self-biased current buffer to provide high output impedance with minimal current change for any input voltage change from noise.

Abstract: A noninvasive remote parameter sensor and sensing method is provided that is particularly suited for the remote monitoring of skin temperature. The sensor and sensing method utilize luminescence-based sensors that are non-toxic and non-irritating to the skin. The sensor preferably utilizes one or more types of fluorophores that are embedded in a soft hydrogel. The sensor is illuminated with excitation light, and temperature is monitored by detecting and analyzing the emission light from the fluorophores. Because a soft hydrogel is used, the sensor can be gently wiped off the skin at the conclusion of temperature measurements.

Abstract: The present invention relates to certain novel shRNA molecules and methods of use thereof. According to certain embodiments of the present invention, methods for reducing the expression level of a target gene are provided. Such methods generally comprise providing a cell with one or more precursor nucleic acid sequences that encode two or more RNA molecules. A first RNA molecule comprises a double stranded sequence, which includes a guide strand sequence that is complementary to a portion of an mRNA transcript encoded by the target gene. In addition, a second RNA molecule comprises a second double stranded sequence, which includes a second guide strand sequence that is partially complementary to a portion of the mRNA transcript encoded by the target gene. Preferably, the second guide strand sequence comprises one or more bases that are mismatched with a nucleic acid sequence of the mRNA transcript encoded by the target gene.

Abstract: Compositions and methods for cancer treatment are discloses herein. More specifically the present invention describes an autologous cancer vaccine genetically modified for Furin knockdown and GM-CSF expression. The vaccine described herein attenuates the immunosuppressive activity of TGF-? through the use of bi-functional shRNAs to knock down the expression of furin in cancer cells, and to augment tumor antigen expression, presentation, and processing through expression of the GM-CSF transgene.

Abstract: In an embodiment, a semiconductor device is provided. The semiconductor device may include a substrate having a main processing surface, a first source/drain region comprising a first material of a first conductivity type, a second source/drain region comprising a second material of a second conductivity type, wherein the second conductivity type is different from the first conductivity type, a body region electrically coupled between the first source/drain region and the second source/drain region, wherein the body region extends deeper into the substrate than the first source/drain region in a first direction that is perpendicular to the main processing surface of the substrate, a gate dielectric disposed over the body region, and a gate region disposed over the gate dielectric, wherein the gate region overlaps with at least a part of the first source/drain region and with a part of the body region in the first direction.

Abstract: In one embodiment, a circuit for matrix decomposition is provided. The circuit includes an input circuit for receiving a first matrix. A permutation circuit is coupled to the input circuit and configured to interchange columns of the first matrix according to a selected permutation to produce a second matrix. A systolic array is coupled to the permutation circuit and configured to perform QR decomposition of the second matrix to produce a third matrix and a fourth matrix. A reverse permutation circuit is coupled to the systolic array and configured to interchange rows of the third matrix according to an inverse of the selected permutation to produce a first factor matrix and interchange rows of the fourth matrix according to the inverse of the selected permutation to produce a second factor matrix.

Abstract: Systems and methods of testing a reference cell in a memory array are disclosed. In a particular embodiment, a method of testing a reference cell in a memory array includes coupling a first reference cell of a first reference cell pair of the memory array to a first input of a first sense amplifier of the memory array. The method also includes providing a reference signal to a second input of the first sense amplifier. The reference signal is associated with a second reference cell pair of the memory array.

Abstract: The present invention is directed toward a method, device, and system for enhancing web security by masking a URL embedded in at least some portion of web content. A session dependent URL is generated and masked on a server side prior to being distributed to a customer for viewing. The session dependent URL is only active during the session in which it was generated. After the session has ended information relating to the session, web content, and masking of the URL is purged from memory.

Abstract: Disclosed is an improved approach for managing, tracking, and querying hierarchical data in layouts. According to some aspects, hierarchical grids are employed utilizing a scheme that organizes physical objects into a set of gradually refined grids that avoids the need to maintain duplicates while enhancing the desirable characteristics of existing schemes, including fast query times, fast data structure initialization and reduced memory footprint. Each grid-cell may be further partitioned into sub-containers to more efficiently provide space pruning during query operations. According to one approach, structures maintained to track existence of objects in a descendent hierarchy.

Abstract: A data link layer tunneling technique improves the throughput of high speed data in noisy wireless environments. Recovering lost frames transmitted between a packet sending unit and a packet receiving unit in a data communications system generally comprises (a) identifying a failure to successfully receive a missed frame at the packet receiving unit; (b) establishing a logical tunnel channel at the packet receiving unit to acknowledge the next successfully received frame; (c) starting a first timer at the packet receiving unit; (c) upon receiving a tunnel establishment request from the packet receiving unit, the packet sending unit resending the missed frame on the logical tunnel channel and starting a second timer; and (d) the packet sending unit resending the missed frame a specified number of times until receiving an acknowledgement from the packet receiving unit.

Abstract: A magnetic writer includes a write pole configured such that the easy magnetic axis is parallel to the vertical length direction of the write pole tip and to the ABS of the recording media. The write pole tip can be a multilayer structure comprising alternating magnetic and nonmagnetic layers with a planar orientation substantially perpendicular to the ABS and with magnetic anisotropy parallel to the vertical length direction of the write pole tip. The alternating magnetic and nonmagnetic layers may be formed by electroplating on a conformal seedlayer in a trench, or by static off axis physical vapor deposition.