Abstract: A system may analyze agricultural materials. The system may include one or more inlets receiving the agricultural materials. The agricultural materials may be a slurry (e.g., soil slurry) including at least one solid and at least one liquid. The system may include a chamber configured to house the agricultural materials. The chamber may include a mixing device configured to mix the agricultural materials. The system may include a flow control device configured to stop the flow of the agricultural materials in a first state, or move the flow of the agricultural materials in a second state. The system may include an agricultural materials density device configured to determine the density of the agricultural materials when the flow of the agricultural materials is stopped in the first state and when the flow of the agricultural materials is moving in the second state.

Abstract: Provided is an individually packaged pod for receptacles of smoking pipes and other smoking devices. The individually packaged pod may have a product, such as herbs or herb mixtures, placed inside the individually packaged pod. The individually packaged pod may include an insert, a ring, and a cover. The insert may be made of a mesh having a convex three-dimensional shape to form a receptacle for receiving the product. The ring may be connected to the insert and configured to maintain the convex three-dimensional shape of the insert. The cover may be made of a sheet material and attached to the ring to enclose the product inside the insert. Upon placing the individually packaged pod into a receptacle of a pipe, a user may ignite the cover and the product inside the individually packaged pod. Burning of the product creates smoke to be inhaled by the user.

Abstract: A feedwell is provided for an inclined plate separator having a separation chamber containing parallel plates defining separation passages. The feedwell includes a plenum defining a plenum chamber external to the separation chamber, an upward-facing deflector surface in the plenum chamber, an inlet for discharging influent fluid onto a receiving region of the deflector surface, and an outlet for discharging the influent fluid out of the plenum and transversely into the separation chamber. The feedwell also includes parallel fins. The fins define between them plenum passages that extend from a fin end to outlet. The fin ends are disposed between the outlet and the receiving region, and are arranged in a horizontal semi-elliptical path defining a center that horizontally coincides with the receiving region.

Abstract: The present invention provides novel, serum-stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles. More particularly, the present invention provides serum-stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (e.g., one or more interfering RNA molecules), methods of making the SNALP, and methods of delivering and/or administering the SNALP (e.g., for the treatment of cancer). In particular embodiments, the present invention provides tumor-directed lipid particles that preferentially target solid tumors. The tumor-directed formulations of the present invention are capable of preferentially delivering a payload such as a nucleic acid to cells of solid tumors compared to non-cancerous cells.

Abstract: A system for processing a workpiece includes a robotic manipulator and an end effector coupled to a working end of the robotic manipulator. The end effector includes a machine tool and an end-effector vacuum clamp that is coupled to the machine tool. The end effector is releasably coupleable to a surface of the workpiece. A processing force is reacted through the end effector and to the workpiece.

Abstract: The present disclosure is directed toward a fire barrier for use in a fire rated movement joint (100) for an internal compartment wall. The fire barrier (132) comprises a strip of intumescent (126) material enclosed in a scrim (134), and the scrim (134) comprises a gusset (136) into which the intumescent (126) expands when reacting to heat.

Abstract: An accessory device for use with a medical device includes a first cuff secured to a distal end of the medical device, a second cuff secured to the medical device proximal of the first cuff, an actuator, and at least one actuation wire extending from the first cuff, through the second cuff, to the actuator.

Abstract: Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein m, n, R2, R3, R5, R6, R7, R8, R9, R10, R11a, R11b, and X are as defined elsewhere herein. Also provided herein are methods of preparing compounds of formula (II). Also provided herein are methods of inhibiting SLC6A19 and methods of treating a SLC6A19-mediated disease, disorder, or condition in an individual in need thereof.

Abstract: A double diaphragm slurry pump (7080) comprises: a pump body (8200) defining a vertical longitudinal axis (LA) and first (8201) and second (8202) pumping chambers; an inlet flow manifold (8203) and an outlet flow manifold (8204) coupled to the pump body; a first pump head (8230a) coupled to the body adjacent the first pumping chamber, the first pump head comprising a longitudinal flow bore (8231) separate from the first pumping chamber and fluidly coupled to the inlet and outlet flow manifolds, an upper air vent bore (8232), and a lower slurry exchange bore (8233), the upper air vent bore and lower slurry exchange bore each fluidly coupling the longitudinal flow bore in turn to the first pumping chamber; and an operating shaft (8240) coupled to a resiliently deformable diaphragm (8241) disposed in the first pumping chamber; wherein the shaft is moveable in a pump stroke to pump a fluid through the longitudinal bore of the first pump head and the first pumping chamber from the inlet flow manifold to the outlet

Abstract: Methods and systems are disclosed that monitor the carbon and hydrogen production of a pyrolysis reactor system and adjust one or more inputs to the reactor system to improve performance when one or both of the monitored carbon and hydrogen production falls outside of a target performance specification. In particular, the ratio of fuel to oxidant (“fuel/oxidant ratio”) supplied to a combustion chamber of the reactor system is adjusted to below a fuel/oxidant equivalence ratio range, defined as 0.9-1.1, when both carbon and hydrogen production falls below a target carbon and hydrogen specification, and adjusted above the fuel/oxidant equivalence ratio range when only the carbon production falls below a target carbon specification. The target specification can include a number of parameters including production rate, morphology (of carbon), and operating temperature.

Abstract: The present invention provides constructs comprising modified riboswitches to regulate expression of a transgene within a subject. Methods of treating a disease, specifically an eye disease, are also contemplated.

Abstract: A physical therapy device. At least one hexagon mount section is mounted onto a backing board. The hexagon mount section includes a plurality of hexagonal cutout sections. At least one peg holder is also mounted onto the backing board. A plurality of pegs is insertable into the peg holder and also into the hexagon mount sections. A board mount is also preferably connected to the backing board. Straps, strap attachment devices and bands may by draped over the board mount.

Abstract: There is provided an ear cup including a housing containing a filter assembly and a motor-driven impeller for creating an airflow through the filter assembly, the housing including an air outlet downstream from the filter assembly for emitting the filtered airflow from the housing. The ear cup further includes an acoustic driver carried by or mounted to, either directly or indirectly, the housing, a reference internal noise sensor disposed within the housing, and a reference ambient noise sensor carried by or mounted to, either directly or indirectly, the housing. The ear cup further includes active noise control circuitry that is configured, in a first operating state, to use a signal provided by the reference internal noise sensor to operate the acoustic driver and, in a second operating state, to use a signal provided by the reference ambient noise sensor to operate the acoustic driver.

Abstract: Described herein is a method for managing media item playback. A method includes presenting a media player in a first portion of a user interface (UI) provided by a first application on a screen of a user device, the media player to provide playback of a first media item from a first post of a plurality of posts of the first application. The method also includes relocating the media player to a second portion of the UI while continuing to provide playback of the first media item by the relocated media player, and receiving a user gesture to scroll through the plurality of posts of the first application on the screen of the user device, the plurality of posts comprising a second post having a second media item. The method further includes upon receiving the user gesture to scroll through the plurality of posts of the first application, allowing a user to view the second media item in the second post while continuing to provide playback of the first media item by the relocated media player.

Abstract: Void-free bottom-up fill of copper in features is achieved on non-copper liner layers. A non-copper liner layer has a higher resistivity than copper. An electroplating solution for plating copper on a non-copper liner layer includes a low copper concentration, high pH, organic additives, and bromide ions as a copper complexing agent. The high pH and the bromide ions do not interfere with the activity of the organic additives. In some implementations, the concentration of copper ions is between about 0.2 g/L and about 10 g/L, a concentration of sulfuric acid is between about 0.1 g/L and about 10 g/L, and a concentration of the bromide ions is between about 20 mg/L and about 240 mg/L. In some implementations, the electroplating solution further includes chloride ions as an additional copper complexing agent at a concentration between about 0.1 mg/L and about 100 mg/L.

Abstract: Disclosed are various embodiments for automated document processing. A linked provider associated with a transaction record is identified. A submission template for the linked provider is then identified, the submission template specifying how to complete a submission using transaction data from the transaction record. Transaction data is then obtained from the transaction record. A submission is then completed based at least in part on the submission template and using the transaction data. Finally, the completed submission is then sent to a provider service associated with the linked provider.

Abstract: This disclosure relates to mRNA therapy for the treatment of ornithine transcarbamylase deficiency (OTCD). mRNAs for use in the invention, when administered in vivo, encode human ornithine transcarbamylase (OTC). mRNA therapies of the disclosure increase and/or restore deficient levels of OTC expression and/or activity in subjects. mRNA therapies of the disclosure further decrease levels of toxic ammonia associated with deficient OTC activity in subjects.

Abstract: The disclosure relates to an assembly comprising an electric motor that simultaneously drives both a pump and a compressor. The assembly can be used in a motor vehicle. The pump can be suited particularly for generating hydraulic fluid flow for steering and braking, or to perform auxiliary functions such as dump bodies for garbage trucks or landscape trucks. Methods of operating the system and manufacturing the system are also provided.

Abstract: An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (e.g., mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The preparation sub-system may comprise a slurry recirculation flow loop configured with devices to stir, measure, and adjust a water to solids ratio of the slurry.