Abstract: Methods and compositions are described for making phenotypically female fertile animals from XY donor cells and suitable host embryos. Culture media and methods are provided for maintaining XY donor cells in culture that after introduction into a host embryo and gestation in a suitable host will result in fertile XY female animals. Methods and compositions are described for making fertile female animals in an F0 generation from a donor XY cell and a host embryo, as are methods for making F1 progeny that are homozygous for a modification from a heterozygous F0 fertile male and a heterozygous F0 fertile female sibling.

Abstract: A humidifier assembly for a CPAP includes a base housing with a gas inlet configured to receive respiratory gas from the CPAP unit. The base housing includes a first connecting device located at a sidewall of the base housing and configured to directly, removably connect the base housing to the CPAP unit. The base housing also includes a second connecting device configured to be coupled to an air delivery hose. The humidifier assembly further includes a liquid storage container that is removably received in the base housing. The liquid storage container includes a liquid storage space configured to store liquid and a humidifying region configured to receive the respiratory gas from the gas feed opening and receive a partial amount of the liquid stored in the liquid storage space to enrich the respiratory gas with moisture.

Abstract: Examples of a multi-region touchpad are disclosed. In one example implementation, a multi-region touchpad may include a multi-region touchpad sensor having a region and a secondary region to receive an input corresponding to a movement against the multi-region touchpad sensor and a touchpad controller. The touchpad controller may process the received input, and may transmit touch position indicative of the received input to a touchpad driver of a computing device communicatively coupled to the touchpad device. Further, the touchpad driver may cause an operating system of the computing device to treat a touch with a touch position beginning in the primary region and extending into the secondary region as a continuous touch. Similarly, the touchpad driver may cause the operating system to treat a touch with a touch position beginning in the secondary region as a navigational command to cause the operating system to perform a navigational function.

Abstract: This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can be used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections. The compounds have the formula: wherein R1 and R2 are independently H, halogen, cyano, haloalkyl, haloalkyloxy or OMe; or R1 and R2 together are —O—CH2— or —O—CF2—O—; R3 is H, halogen, cyano, haloalkyl or haloalkyloxy; R4 is C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkylmethyl or C3-6cycloheteroalkyl, wherein the heteroatom is N or O; R5 is H or CH3; R6 is C1-6alkyl or C3-6cycloalkyl; and A, B, D and E are each, independently, CH, N, O or S, wherein at least one of A, B, D and E is N, and another of A, B, D and E is N, O or S.

Abstract: Disclosed herein are system, method, and computer program product embodiments for bloom filter versioning. A request to add a new value to a first bitmap is received, wherein the first bitmap includes a bit sequence corresponding to a most recently added value. It is determined that the first bitmap has exceeded a threshold. A second bitmap is generated, the second bitmap including more bits than the first bitmap. The first bitmap is deleted based upon a determination that a number of readers accessing the first bitmap is zero.

Abstract: Golf club heads having sensors configured to measure one or more swing parameters are provided. The golf club head may include several gyroscopes and accelerometers. In one embodiment, the club head contains three gyroscopes that measure angular rate data along different orthogonal axes. At least one gyroscope may an analog gyroscope. Accelerometers may provide data regarding the three orthogonal axes associated with the gyroscopes. The club head may further include software and/or hardware that perform computer-executed methods for determining one or more swing parameters. Exemplary club heads may include a display device for displaying an output of the swing parameter(s). Further aspects of the invention relate to novel methods and algorithms for calculating measurements relating to the swing parameters.

Abstract: Systems and methods for synchronized key derivation across multiple conditional access servers are disclosed. In one embodiment, a method for synchronized key derivation to provide playback devices with derived keys for decrypting content includes receiving a request for a first derived key that includes a first asset identifier than identifies a piece of content and a first playback position within the content, determining a first content key starting position and first derived key starting position within the content using the first playback position, where the key starting positions precede the first playback position, determining whether a first content key associated with the first asset identifier and first content key starting position is stored, retrieving the first content key using the first asset identifier and first content key starting position, generating a first derived key using the first content key and first derived key starting position, and sending the derived key.

Abstract: Technology is disclosed herein for compressing, encoding, and otherwise reducing the size of resource files. In at least one implementation, similarity compression is employed to reduce the size of a resource file. In another implementation, map-less encoding is employed to reduce the number of bytes used to represent a resource string. Bit-level compression is employed in another implementation to reduce the quantity of bits used to encode each character in a string. In addition, implementations are disclosed related to technology for naming strings and accelerated string location and retrieval.

Abstract: A propulsion system for a supersonic aircraft includes an engine including an engine core and an engine bypass, a compression surface upstream of the engine, a shroud surrounding the engine configured to direct airflow passing over the compression surface towards the engine, and a plurality of vortex generators positioned upstream of the engine. The vortex generators have a height such that when the supersonic aircraft is flown at a predetermined altitude and predetermined speed, the plurality of vortex generators create vortices that propagate partially outside of a boundary layer formed proximate a surface of a supersonic inlet. The vortices cause a high-velocity portion of the airflow to move towards the engine core and a low-velocity portion of the airflow to move towards the engine bypass. The plurality of vortex generators are disposed aft of a terminal shock and have a height greater than the thickness of the boundary layer.

Abstract: Embodiments relate to coupling a heading sensor to a deflector surface reference for obtaining the deflector heading which can be used in estimation of the deflector angle of attack. A method may comprise: towing a plurality of streamers behind a survey vessel in a body of water, wherein at least one deflector provides a lateral component of force to the streamers; determining a deflector heading over ground using at least measurements from a heading sensor on a surface reference corresponding to the deflector; determining a deflector velocity over ground using at least measurements from a position sensor on the surface reference; determining a water current of the body of water; and estimating a deflector angle of attack based on inputs comprising the deflector heading, the deflector velocity over ground, and the water current.

Abstract: A method for color correcting an input color image having input color values adapted for display on a reference display device having a plurality of input color primaries to account to provide reduced observer metemaric failure on a narrow-band display device. A metamerism correction transform is applied to the input color image to determine an output color image having output color values in an output color space appropriate for display on the narrow-band display device. The metamerism correction transform modifies colorimetry associated with the input colors to provide output color values such that an average observer metameric failure is reduced for a distribution of target observers.

Abstract: A minimally invasive intervertebral implant includes a circuitous body defining a luminal axis extending longitudinally therethrough. The circuitous body includes proximal and distal ends oppositely disposed along a lateral axis of the circuitous body. Each of the proximal and distal ends includes an aperture disposed therethrough such that the circuitous body includes a first configuration wherein the proximal and distal ends are at a maximum separation and a second configuration wherein the proximal and distal ends are closer together than in the first configuration.

Abstract: A hearing aid device has an antenna device. The antenna device is configured to receive and/or transmit electromagnetic waves of a predetermined wavelength lambda. The antenna device has an energy coupling device which is configured to supply or to draw electrical energy to or from the antenna device. The antenna device has a first conductor and a second conductor, which are in energy exchange with the energy coupling device, extend away from the energy coupling device in different directions and are arranged a short distance from a third conductor. A first ohmic connection between the first conductor and the third conductor and a second ohmic connection between the second conductor and the third conductor are arranged at a predefined distance from the energy coupling device.

Abstract: The present invention relates to compounds according to Formula (I) or a pharmaceutically acceptable salt or solvate thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or condition.

Abstract: The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

Abstract: Aspects of the subject disclosure may include, for example, a transmission medium for propagating electromagnetic waves. The transmission medium can include a plurality of cores for selectively guiding an electromagnetic wave of a plurality of electromagnetic waves longitudinally along each core, and a shell surrounding at least a portion of each core for reducing exposure of the electromagnetic wave of each core. Other embodiments are disclosed.

Abstract: Provided is a method for energy recuperation in the expansion of processed natural gas before the delivery of the latter to an acetylene production plant (H). The method includes delivery of heated processed natural gas to an expansion device and expansion of the processed natural gas in the expansion device to a pressure of 2 bar to 8 bar. The expansion device is a piston expansion machine which is operated by the expansion of the processed natural gas and which generates energy. Also provided is a plant for energy recuperation in the expansion of processed natural gas.

Abstract: A device may provision two or more servers, each of the servers including a network interface. In addition, the device may enable the network interface in each of the provisioned servers, create a shared volume, assign the shared volume to each of the provisioned servers, and enable a clustering application on each of the provisioned servers to form a cluster comprising the provisioned servers, the cluster having a heartbeat via the network interfaces.

Abstract: The present invention provides for a method and system to compensate phase offset caused by the IC (integrated circuit) by making use of factory measurement stored as trim-data in the IC. In the final customer product, the trim-data is mapped to the actual platform environment such that the respective phase offset can be compensated.