Patents by Inventor Aaron Beaty BEELER

Aaron Beaty BEELER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BODIPY-BASED DYES FOR DIGITAL SPATIAL PROTEOMICS
    Publication number: 20250076305
    Abstract: The disclosure provides probes comprising dipyrromethane-BF2 derivatives which exhibits different fluorescent spectral properties when conjugated to the amnio acids, compositions and kits comprising same. The disclosure also provides methods for detecting/identifying amino acids and sequencing polypeptide molecules by conjugating a dipyrromethane-BF2 derivative which exhibits different fluorescent spectral properties when conjugated to the amnio acids.
    Type: Application
    Filed: November 18, 2024
    Publication date: March 6, 2025
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Aaron Beaty BEELER, Andrew Emili, Jason Michael Lenihan, Nathaniel Ryan Hendrick, Ichun Anderson Chen
  • BODIPY-based dyes for digital spatial proteomics
    Patent number: 12181479
    Abstract: The disclosure provides probes comprising dipyrromethane-BF2 derivatives which exhibits different fluorescent spectral properties when conjugated to the amino acids, compositions and kits comprising same. The disclosure also provides methods for detecting/identifying amino acids and sequencing polypeptide molecules by conjugating a dipyrromethane-BF2 derivative which exhibits different fluorescent spectral properties when conjugated to the amino acids.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: December 31, 2024
    Assignee: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Aaron Beaty Beeler, Andrew Emili, Jason Michael Lenihan, Nathaniel Ryan Hendrick, Ichun Anderson Chen
  • BODIPY-BASED DYES FOR DIGITAL SPATIAL PROTEOMICS
    Publication number: 20230194539
    Abstract: The disclosure provides compositions, kits, and methods for detecting/identifying amino acids and sequencing polypeptide molecules.
    Type: Application
    Filed: December 22, 2022
    Publication date: June 22, 2023
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Aaron Beaty BEELER, Andrew EMILI, Jason Michael LENIHAN, Nathaniel Ryan HENDRICK, Ichun Anderson CHEN
  • Selective histone deacetylase 8 inhibitors
    Patent number: 10087149
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that benefit from inhibition of HDAC8 activity.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: October 2, 2018
    Assignees: TRUSTEES OF BOSTON UNIVERSITY, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Aaron Beaty Beeler, John A. Porco, Jr., Oscar J. Ingham, James E. Bradner
  • SELECTIVE HISTONE DEACETYLASE 8 INHIBITORS
    Publication number: 20150352079
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8).
    Type: Application
    Filed: January 24, 2014
    Publication date: December 10, 2015
    Inventors: Aaron Beaty BEELER, John A. PORCO, JR., Oscar J. INGHAM, James E. BRADNER