Abstract: Aspects of the disclosure relate to using vehicle telematics data to assess parameters associated with vehicle operation. In some instances, a driving assessment system may include a first computing device associated with a user in a vehicle and a second computing located remotely from the first computing device. The first computing device may collect, by way of one or more of an accelerometer and global positioning system (GPS), vehicle operational data and vehicle locational information associated with the vehicle and corresponding to a trip of the vehicle and may transmit such information to the second computing device. The second computing device may identify actionable and second order actionable trip data from the vehicle operational data and vehicle locational information and may calculate a behavior score for the trip.

Abstract: The present disclosure provides IL2 proproteins comprising an IL2 moiety that is masked with an IL2R? moiety and a protease-cleavable linker, configured such that the IL2R? moiety is released from the IL2 moiety upon the action of a protease, e.g., at a tumor site. The IL2 proproteins optionally further comprise a targeting moiety, e.g., a targeting moiety that recognizes a tumor-associated antigen and directs the proprotein to a tumor site. The disclosure further provides pharmaceutical compositions comprising the IL2 proproteins, and methods of use of the IL2 proproteins in therapy, as well as nucleic acids encoding the IL2 proproteins, recombinant cells that express the IL2 proproteins and methods of producing the IL2 proproteins.

Abstract: The present disclosure relates to IL12 receptor agonists with improved therapeutic profiles.

Abstract: The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.

Abstract: A system and urine sensing devices for and method of monitoring kidney function is disclosed, wherein the system and method can be used for the early detection of acute kidney injury (AKI). Namely, a kidney function monitoring system provides a portable urine monitor system that can provide real-time and continuous feedback about urine output and/or level of at least one urinary component (e.g., sodium). The kidney function monitoring system further comprises at least one urine sensing device, wherein the urine sensing device comprises a digital weight scale, a stand onto which a urine collection vessel can be positioned, and an interface between the digital weight scale and the stand that transfers the force of the stand and contents of the urine collection vessel to the digital weight scale. Further, the portable monitoring device comprises an adaptive and modular self-learning algorithm for the real-time assessment of AKI risk.

Abstract: The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.

Abstract: The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.

Abstract: The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.

Abstract: The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.

Abstract: Technologies for optimizing transmitter equalization include a computing device having a data port and a retimer. The retimer includes two serial data links, a clock recovery device, and a signal repeater. One serial data link of the retimer is connected to the data port. A bit-error rate test instrument (BERT) is connected to the other serial data link of the retimer and sweeps through multiple transmitter equalization settings while sending a compliance pattern. The retimer sends back the compliance pattern in a loopback mode. The BERT measures bit-error rate data, and an optimized transmitter equalization setting is determined based on the bit-error rate data. An end device may be configured with the optimized transmitter equalization setting and may be connected to the retimer instead of the BERT. The data port may be a PCI Express port or a backplane Ethernet port. Other embodiments are described and claimed.

Abstract: The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.

Abstract: A system and urine sensing devices for and method of monitoring kidney function is disclosed, wherein acute kidney injury (AKI). Namely, a kidney function monitoring system provides a portable urine monitor system that can provide real-time and continuous feedback about urine output and/or level of at least one urinary component (e.g., sodium). The kidney function monitoring system further comprises at least one urine sensing device, wherein the urine sensing device comprises a digital weight scale, a stand onto which a urine collection vessel can be positioned, and an interface between the digital weight scale and the stand that transfers the force of the stand and contents of the urine collection vessel to the digital weight scale. Further, the portable monitoring device comprises an adaptive and modular self-learning algorithm for the real-time assessment of AKI risk.

Abstract: Disclosed is a drill rig having two master skids. Wherein prior to assembly of the drill rig, the master skids include a base box structure and a supported box structure arranged in a nested relationship. Additionally, the base box structures house hydraulic components and support components necessary to raise and support the supported box structure at an operational position. Further, the base box structures includes hydraulic components necessary to raise the drill rig mast to an operational position.

Abstract: The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.

Abstract: A method and system for improving the effectiveness of cardioversion and defibrillation through the ability to reduce transthoracic impedance. A method and system of decreasing transthoracic impedance that allows standardized pressure to be applied directly over desired defibrillator patches. This system reduces transthoracic impedance by increasing effective pressure on desired patches through use of a manual depressor device which incorporates a deformable patient body interface and mechanical and or electronic mechanisms to provide qualitative and or quantitative feedback on the force being applied to said patches. By depressing the device over desired external adhesive electrode patches until an audio and or visual signal indicates sufficient applied pressure, increased patch to skin contact is achieved to decrease the effective transthoracic impedance of a patient upon delivery of a defibrillation shock.

Abstract: A method and system for improving the effectiveness of cardioversion and defibrillation through the ability to reduce transthoracic impedance. A method and system of decreasing transthoracic impedance that allows standardized pressure to be applied directly over desired defibrillator patches. This system reduces transthoracic impedance by increasing effective pressure on desired patches through use of a manual depressor device which incorporates a deformable patient body interface and mechanical and or electronic mechanisms to provide qualitative and or quantitative feedback on the force being applied to said patches. By depressing the device over desired external adhesive electrode patches until an audio and or visual signal indicates sufficient applied pressure, increased patch to skin contact is achieved to decrease the effective transthoracic impedance of a patient upon delivery of a defibrillation shock.

Abstract: Disclosed is a drill rig having two master skids. Wherein prior to assembly of the drill rig, the master skids include a base box structure and a supported box structure arranged in a nested relationship. Additionally, the base box structures house hydraulic components and support components necessary to raise and support the supported box structure at an operational position. Further, the base box structures includes hydraulic components necessary to raise the drill rig mast to an operational position.