Abstract: The invention provides a method for detection of allergic inflammation in a subject that comprises assaying a test sample of peripheral blood from the subject for a marker of DNA damage. An elevated amount of marker present in the test sample compared to control sample is indicative of inflammation. The method can be adapted for quantitatively monitoring the efficacy of treatment of allergic inflammation in a subject. Markers of DNA damage include single- and/or double-stranded breaks in leukocytes, oxidative DNA damage in leukocytes, or a marker of nitric oxide oxidative activity (protein nitrosylation in leukocytes). This unexpected discovery of markers of systemic genotoxicity present in circulating leukocytes enables detection of allergic inflammation with a relatively simple and minimally invasive assay using peripheral blood.

Abstract: The invention provides a method for detection of allergic inflammation in a subject that comprises assaying a test sample of peripheral blood from the subject for a marker of DNA damage. An elevated amount of marker present in the test sample compared to control sample is indicative of inflammation. The method can be adapted for quantitatively monitoring the efficacy of treatment of allergic inflammation in a subject. Markers of DNA damage include single- and/or double-stranded breaks in leukocytes, oxidative DNA damage in leukocytes, or a marker of nitric oxide oxidative activity (protein nitrosylation in leukocytes). This unexpected discovery of markers of systemic genotoxicity present in circulating leukocytes enables detection of allergic inflammation with a relatively simple and minimally invasive assay using peripheral blood.

Abstract: This is a surgical scalpel that has a skirt preventing blood, pus or waste fluids from squirting into the Doctors face and body while the Doctor is performing any procedure that entails cutting into a human or animal. It is the correct scalpel to use when performing the initial incision or cut.

Abstract: A harness for use with breathing apparatus has: a flexible hip plate 12 and a flexible bandolier-style shoulder panel 14, linked together by a strap 15, and a waist belt 16 fastenable by a sprung fastener. In use, the flexible hip plate 12 rests against the hip of a user (the left hip in this example), the waist belt is fitted around the waist of the user, and the shoulder panel 14 rests against the shoulder opposite to the hip against which the flexible plate is resting (the right shoulder in this example). At least the bandolier-style panel 14, and optionally also the hip plate 12 of the harness 10, are made of a resilient material which, though flexible, allows the harness substantially to retain its operational configuration even when not being worn.

Abstract: A harness for use with breathing apparatus has: a flexible hip plate 12 and a flexible bandolier-style shoulder panel 14, linked together by a strap 15, and a waist belt 16 fastenable by a sprung fastener. In use, the flexible hip plate 12 rests against the hip of a user (the left hip in this example), the waist belt is fitted around the waist of the user, and the shoulder panel 14 rests against the shoulder opposite to the hip against which the flexible plate is resting (the right shoulder in this example). At least the bandolier-style panel 14, and optionally also the hip plate 12 of the harness 10, are made of a resilient material which, though flexible, allows the harness substantially to retain its operational configuration even when not being worn. The material is preferably a composite, and may comprise closed cell, open face foam, such as compression moulded EVA foam. Two layers of such foam may be used in a sandwich construction, and may be glued or otherwise bonded together.

Abstract: A harness for use with breathing apparatus has: a flexible hip plate 12 and a flexible bandolier-style shoulder panel 14, linked together by a strap 15, and a waist belt 16 fastenable by a sprung fastener. In use, the flexible hip plate 12 rests against the hip of a user (the left hip in this example), the waist belt is fitted around the waist of the user, and the shoulder panel 14 rests against the shoulder opposite to the hip against which the flexible plate is resting (the right shoulder in this example). At least the bandolier-style panel 14, and optionally also the hip plate 12 of the harness 10, are made of a resilient material which, though flexible, allows the harness substantially to retain its operational configuration even when not being worn. The material is preferably a composite, and may comprise closed cell, open face foam, such as compression moulded EVA foam. Two layers of such foam may be used in a sandwich construction, and may be glued or otherwise bonded together.

Abstract: A hose dispenser has a rotatable reel 10, holding a coiled hose 12 suitable for conveying breathable gas, mounted on a tubular steel frame 14. The reel has a pivoting arm 16, which has a portion defining an aperture, or “eye” 18 fitted thereon. The hose is threaded through the eye 16 so that the free end of the hose protrudes through the eye. The free end of the hose is fitted with a resilient frusto-conical protective hood 20. The hood provides two functions. First, it enables the free end of the hose to engage the eye of the arm 16, and secondly, it protects a valve 22, located on the free end of the hose, from damage. Another valve 24 is provided in the centre of the reel, which is connected to the other end of the hose. In use, the free end of the hose is carried by an operative, or is attached to breathing apparatus worn by the operative, and the other end is connected to a source containing gas for breathing. The arm 16 is mounted pivotally on the reel.

Abstract: A harness for use with breathing apparatus has: a flexible hip plate 12 and a flexible bandolier-style shoulder panel 14, linked together by a strap 15, and a waist belt 16 fastenable by a sprung fastener. In use, the flexible hip plate 12 rests against the hip of a user (the left hip in this example), the waist belt is fitted around the waist of the user, and the shoulder panel 14 rests against the shoulder opposite to the hip against which the flexible plate is resting (the right shoulder in this example). At least the bandolier-style panel 14, and optionally also the hip plate 12 of the harness 10, are made of a resilient material which, though flexible, allows the harness substantially to retain its operational configuration even when not being worn. The material is preferably a composite, and may comprise closed cell, open face foam, such as compression moulded EVA foam. Two layers of such foam may be used in a sandwich construction, and may be glued or otherwise bonded together.

Abstract: A hose dispenser has a rotatable reel 10, holding a coiled hose 12 suitable for conveying breathable gas, mounted on a tubular steel frame 14. The reel has a pivoting arm 16, which has a portion defining an aperture, or “eye” 18 fitted thereon. The hose is threaded through the eye 16 so that the free end of the hose protrudes through the eye. The free end of the hose is fitted with a resilient frusto-conical protective hood 20. The hood provides two functions. First, it enables the free end of the hose to engage the eye of the arm 16, and secondly, it protects a valve 22, located on the free end of the hose, from damage. Another valve 24 is provided in the centre of the reel, which is connected to the other end of the hose. In use, the free end of the hose is carried by an operative, or is attached to breathing apparatus worn by the operative, and the other end is connected to a source containing gas for breathing.