Patents by Inventor Aaron Coffin

Aaron Coffin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF TREX1
    Publication number: 20240262814
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: May 4, 2022
    Publication date: August 8, 2024
    Inventors: Julian R. Levell, Aaron Coffin, Avinash Khanna, Jonathan E. Wilson
  • MODULATORS OF TREX1
    Publication number: 20240246946
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: April 25, 2022
    Publication date: July 25, 2024
    Inventors: Julian R. Levell, Aaron Coffin, Mary-Margaret Zablocki, Jonathan E. Wilson, Avinash Khanna, David J. Guerin, William T. McElroy, Jennifer L. Rocnik
  • SUBSTITUTED BENZAMIDES AS MODULATORS OF TREX1
    Publication number: 20230233541
    Abstract: Provided are compounds of Formula (I): (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: May 27, 2021
    Publication date: July 27, 2023
    Inventors: Mary-Margaret Zablocki, Kennedy Taveras, Jonathan E. Wilson, Aaron Coffin, Julian R. Levell, Aravind Prasad Medikonda
  • MODULATORS OF TREX1
    Publication number: 20230167070
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: April 30, 2021
    Publication date: June 1, 2023
    Inventors: Julian R. Levell, Jonathan E. Wilson, Aaron Coffin, Kennedy Taveras
  • Sphingosine-1-phosphate (SIP) receptor agonists
    Patent number: 7759370
    Abstract: The invention provides compounds formula I, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or S1P receptors.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: July 20, 2010
    Assignee: Praecis Pharmaceuticals
    Inventors: Ghotas Evindar, Hongfeng Deng, Sylvie Bernier, Gang Yao, Aaron Coffin, Hongfang Yang
  • AGONISTS OF SPHINGOSINE-1 PHOSPHATE RECEPTOR (SLP)
    Publication number: 20100016260
    Abstract: The invention provides compounds of formula I and formula II, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or SIP receptors.
    Type: Application
    Filed: August 1, 2007
    Publication date: January 21, 2010
    Applicant: PRAECIS PHARMACEUTICALS INCORPORATED
    Inventors: Hongfeng Deng, Ghotas Evindar, Sylvie Bernier, Gang Yao, Aaron Coffin, Hongfang Yang, Raksha A. Acharya
  • CHEMICAL COMPOUNDS
    Publication number: 20100009936
    Abstract: The invention provides compounds formula I, their preparation, and their use as pharmaceutically active immuno-suppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or SIP receptors.
    Type: Application
    Filed: August 1, 2007
    Publication date: January 14, 2010
    Applicant: PRAECIS PHARMACEUTICALS INCORPORATED
    Inventors: Ghotas Evindar, Hongfeng Deng, Sylvie Bernier, Gang Yao, Aaron Coffin, Hongfang Yang
  • Chemical compounds
    Publication number: 20080096938
    Abstract: The invention provides compounds formula I, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or S1P receptors.
    Type: Application
    Filed: August 1, 2007
    Publication date: April 24, 2008
    Applicant: Praecis Pharmaceuticals Incorporated
    Inventors: Ghotas Evindar, Hongfeng Deng, Sylvie Bernier, Gang Yao, Aaron Coffin, Hongfang Yang
  • Chemical compounds
    Publication number: 20080070866
    Abstract: The invention provides compounds of formula I and formula II, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or S1P receptors.
    Type: Application
    Filed: August 1, 2007
    Publication date: March 20, 2008
    Applicant: Praecis Pharmaceuticals Incorporated
    Inventors: Hongfeng Deng, Ghotas Evindar, Sylvie Bernier, Gang Yao, Aaron Coffin, Hongfang Yang, Raksha Acharya