Abstract: Disclosed herein are skin care compositions, comprising vitamin E (e.g., alpha-tocopherol), a thiourea derivative of histidine (e.g., ergothioneine), a vitamin B3 compound (e.g., niacinamide) and/or a pyrrolidone carboxylic acid and/or a salt thereof (e.g., sodium PCA) as well as to methods of using these compositions.

Abstract: A model-assisted system for extracting patient information. A processor may be programmed to access a database storing one or more medical records associated with a patient and determine, using a first machine learning model and based on unstructured information included in the one or more medical records, whether the patient is associated with a condition. The processor may further be programmed to identify a date associated with the patient and determine, using a second machine learning model and based on the unstructured information, whether the patient is associated with the condition relative to the date. The processor may generate an output indicating whether the patient is associated with the condition and whether the patient is associated with the condition relative to the date.

Abstract: Aspects of the present invention relate to personal care compositions for improving the health keratin and, particularly, for improving the health and appearance of skin. The personal care composition may include a personal care composition containing a hyaluronic acid system, one or more peptide, and an extract comprising kangaroo paw flower extract. The hyaluronic acid system typically comprises a plurality of hyaluronic acids.

Abstract: The disclosure relates to skin care compositions comprising an effective amount of one or more hydrophilic vitamins and an effective amount of a low-molecular weight hyaluronic acid or an alkali metal hyaluronate (<avg. 75 kDa) (e.g., avg. 35-avg. 60 kDA) (e.g., about avg. 50 kDA), as well as to methods of using and of making these compositions.

Abstract: Disclosed herein are skin care compositions, comprising vitamin E (e.g., alpha-tocopherol), a thiourea derivative of histidine (e.g., ergothioneine), a vitamin B3 compound (e.g., niacinamide) and/or a pyrrolidone carboxylic acid and/or a salt thereof (e.g., sodium PCA) as well as to methods of using these compositions.

Abstract: Disclosed herein are skin care compositions, comprising vitamin E (e.g., alpha-tocopherol), a thiourea derivative of histidine (e.g., ergothioneine), a vitamin B3 compound (e.g., niacinamide) and/or a pyrrolidone carboxylic acid and/or a salt thereof (e.g., sodium PCA) as well as to methods of using these compositions.

Abstract: A computer-implemented process includes providing a request to access content associated with a website; receiving web page information associated with the website, and data for displaying a notification that indicates availability of a native computer application that is associated with the website; providing a request to access information associated with the native computer application; receiving information associated with the native computer application that describes interactions between a plurality of users of an application marketplace and a component of the application marketplace that provides and receives information related to the native computer application; and displaying the descriptive information for viewing by a user, including displaying information that indicates the interactions between the plurality of users and the component of the application marketplace.

Abstract: Methods, compositions and kits for reducing renal tissue toxicity in a subject caused by a kidney damaging agent are provided. The methods comprise administering to the subject: (i) a kidney damaging agent; (ii) a PPARA activator; and (iii) an inhibitor of a cellular pathway selected from the group consisting of C/EBP, PPARG, ER stress, GLUT2 and SGLT1/2; or (i) a kidney damaging agent; (ii) a SGLT2 inhibitor; and (iii) a PPARA activator, a C/EBP inhibitor, a PPARG inhibitor, or an ER stress inhibitor.

Abstract: A prospecting software platform relating to employer-sponsored healthcare and pension plans, including functionality that identifies unique prospecting opportunities and generates the contact information of key decisionmakers, enabling an end-to-end prospecting experience. The prospecting platform is configured for third-party administrators and other plan professionals to identify new client leads based on aggregated Form 5500 data, Form 990 data, data from LINKEDIN profiles, and personal contact information. The software platform includes artificial intelligence algorithms for filtering and aggregating data to identify new opportunities.

Abstract: Solid cleansing compositions and methods for treating, decreasing, reducing, or preventing hyperpigmentation of skin, and/or methods for regulating melanin in or on skin are provided. The solid cleansing composition may include a delivery vehicle and one or more whitening agents. The whitening agents may include one or more of kojic acid, phenylethyl resorcinol, or combinations thereof. The whitening agents may be configured to regulate melanin in or on skin, and the delivery vehicle may be configured to stabilize the one or more whitening agents.

Abstract: Disclosed are personal care compositions, e.g., skin care compositions, comprising an acyl glutamate, e.g., sodium cocoyl glutamate, in an amount of from 1% to 10% by weight of the composition and at least one topically active compound, wherein the at least one topically active compound comprises a vitamin, as well as to methods of using these compositions.

Abstract: Methods and apparatus for producing virtual concerts or other online collaborative events. One or more musicians or other presenters or contributors at disparate geolocations transmit continuums of audio and/or image data as well as synchronization data continuums. Digital processing may be used to superimpose musicians or other presenters or contributors onto a virtual background (such as a concert stage or other virtual environment). Audio and video feeds from multiple musicians or other presenters or contributors may be synchronized to give the appearance of each being on the same stage in a 2D, 3D or virtual reality (VR) environment. Multiple continuums of audio data may be transmitted at different speeds and quality in order to allow musicians, presenters or other contributors to remain synchronized while a remote production studio receives high quality data transmissions for generation of a combinative, immersive, multi-dimensional end user audio/visual experience.

Abstract: Separable articles of clothing such as trousers to allow for field removal of the lower portion of the trousers are disclosed while maintaining control of a duty belt attached to an upper portion. Two or more separate portions of trousers may be removably attached by an attachment mechanism, such as a zipper. The zipper can be unzipped to allow for restroom use without completely removing the trousers. This may be especially useful for first responders, or other professions requiring complex trousers and a need to maintain control of their duty belt and its contents at all times.

Abstract: An encrypted security system and associated methods for controlling physical access. The system includes a security server configured to receive a request for authentication from a mobile device, the request having information identifying the mobile device and a physical access control device. The security server forwards an encryption message having a plurality of unique identifiers to the physical access control device via the mobile device. The physical access control device is configured to authenticate the plurality of unique identifiers in the encryption message and operate an access control mechanism.

Abstract: A computer-implemented process includes providing a request to access content associated with a website; receiving web page information associated with the website, and data for displaying a notification that indicates availability of a native computer application that is associated with the website; providing a request to access information associated with the native computer application; receiving information associated with the native computer application that describes interactions between a plurality of users of an application marketplace and a component of the application marketplace that provides and receives information related to the native computer application; and displaying the descriptive information for viewing by a user, including displaying information that indicates the interactions between the plurality of users and the component of the application marketplace.

Abstract: An encrypted security system and associated methods for controlling physical access are described. The system includes a security server configured to receive a request for authentication from a mobile device, the request including information identifying the mobile device and a physical access control device. The security server forwards an encryption message including a plurality of unique identifiers to the physical access control device via the mobile device. The physical access control device is configured to authenticate the plurality of unique identifiers in the encryption message and operate an access control mechanism.

Abstract: A system for determining a carbon footprint includes a graphical user interface (GUI), including a display, a processor, and a memory. The memory includes instructions stored thereon, which, when executed by the processor, cause the system to receive input from the GUI, the input including a travel itinerary inquiry, determine a provider listing based on the received travel itinerary inquiry, display the determined provider listing on the GUI, receive a second input from the GUI, the second input including a listing selection, determine a carbon footprint value based on the listing selection, and display the carbon footprint value and the listing selection on the GUI. The travel itinerary inquiry is at least one of an accommodations inquiry, transportation inquiry, or experiences inquiry.

Abstract: An implantable ocular drug delivery system can include inserting an implantable device into an eye, where the device contains therapeutics intended to be released for local or systemic effects. In some implantable device embodiments, the device includes a microchannel intended to reduce intraocular pressure. In some implantable device embodiments, the device includes a microchannel intended to treat dry eye.

Abstract: Devices can be implanted in an eye to treat glaucoma and/or dry eye. The devices described herein include a body defining a lumen and having first and second ends and external and lumenal surfaces. The body has a length sufficient to provide fluid communication between the anterior chamber and tear film of the eye through the lumen when the device is implanted in the sclera. The body can include a radiused distal edge. A distal end portion of the body can be laterally flared. The body can include a mid-body portion that is laterally narrower than distal and proximal end portions of the body. Methods of treating glaucoma and/or dry eye, wherein the device is implanted in the sclera of an afflicted eye, are also described.

Abstract: Monitoring glucose concentration in aqueous humor can include inserting an implantable device into an eye and determining glucose concentration as a function of glucose sensed at the implantable device. In some implantable device embodiments, the device includes a polymer layer comprising a material that changes volume in response to varying glucose concentrations of the aqueous humor. A pressure sensor in the device can detect the changes in volume. In some implantable device embodiments, the device includes electrodes for determining the glucose concentration.