Patents by Inventor Aaron Cote

Aaron Cote has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220016031
    Abstract: A process for preparing and isolating pharmaceutical active ingredient particles having a particle size of between about 0.1 and 30 microns, wherein a slurry comprising the active ingredient and one or more pharmaceutically acceptable excipients is fed into a thin film evaporator under suitable conditions for less than 10 minutes sufficient to generate solid matrix particles comprising active ingredient and one or more excipients, wherein the particles have less than 5% residual solvent.
    Type: Application
    Filed: September 29, 2021
    Publication date: January 20, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Luke R. Schenck, David J. Lamberto, Joseph L. Kukura, II, Francisco J. Guzman, Aaron Cote, Athanas Koynov
  • Publication number: 20200331867
    Abstract: The application relates to a process to produce large isoxazoline compound particles which comprises initiating crystallization and then maintaining the temperature of the crystallization in the metastable region by removing, reheating and recycling a portion of the solvent thereby allowing the existing crystals to grow larger while minimizing the formation of newer smaller crystals.
    Type: Application
    Filed: November 6, 2018
    Publication date: October 22, 2020
    Applicant: Intervet Inc.
    Inventors: Luke Ryan Schenck, Athanas Koynov, George X. Zhou, Aaron Cote
  • Publication number: 20200261365
    Abstract: A process for preparing and isolating pharmaceutical active ingredient particles having a particle size of between about 0.1 and 30 microns, wherein a slurry comprising the active ingredient and one or more pharmaceutically acceptable excipients is fed into a thin film evaporator under suitable conditions for less than 10 minutes sufficient to generate solid matrix particles comprising active ingredient and one or more excipients, wherein the particles have less than 5% residual solvent.
    Type: Application
    Filed: December 13, 2016
    Publication date: August 20, 2020
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Luke R. Schenck, David J. Lamberto, Joseph L. Kukura, II, Francisco J. Guzman, Aaron Cote, Athanas Koynov
  • Publication number: 20160243976
    Abstract: The present invention relates to cargo load lock system. The cargo load lock may include an upper foot, a telescoping tubular pole, a gripping foot and a pair of forks. The cargo load lock may be coupled to a pallet by the pair of forks to better secure cargo against a surface within a cargo carrier in order to keep the cargo in place. The cargo load lock system includes a device for tightening the upper foot and the gripping foot against a pallet and the interior portion of the cargo truck or the trailer, the device for tightening is adapted to shorten or extend the length of the telescoping tubular pole in a secure position. The gripping foot may have the pair of forks, a housing with a plurality of nubs and corresponding holes or a fork plate to accommodate insertion into the pallet.
    Type: Application
    Filed: February 25, 2015
    Publication date: August 25, 2016
    Inventor: Aaron Cote
  • Publication number: 20090111997
    Abstract: The invention encompasses a method for making an amorphous solid of a water-insoluble pharmaceutical comprising: (1) dissolving the water-insoluble pharmaceutical in a water-miscible solvent, optionally with water, to make a solution; (2)(i) rapidly mixing the solution with an antisolvent, wherein the antisolvent is water, at low temperature to precipitate an amorphous solid of the water-insoluble pharmaceutical, or (ii) rapidly mixing the solution with an antisolvent, wherein the antisolvent is water, to precipitate an amorphous solid of the water-insoluble pharmaceutical and subsequently cooling to low temperature; and (3) isolating the amorphous solid of the water-insoluble pharmaceutical. In an embodiment of the invention, the rapid mixing is conducted using an impinging jet device.
    Type: Application
    Filed: November 17, 2006
    Publication date: April 30, 2009
    Inventors: Aaron Cote, Hsien-Hsin Tung
  • Publication number: 20070129548
    Abstract: Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner.
    Type: Application
    Filed: December 4, 2006
    Publication date: June 7, 2007
    Inventors: Lushi Tan, Robert Meissner, Wenjie Li, James Perkins, Aaron Cote, Joyce Stellabott, Yuan-Hon Kiang