Patents by Inventor Aaron D. WROBLESKI

Aaron D. WROBLESKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Notch pathway signaling inhibitor compounds
    Patent number: 10450317
    Abstract: The present invention provides the following compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing said compounds useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing loss caused by auditory hair cell loss, and inducing auditory hair cell generation.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: October 22, 2019
    Assignees: Eli Lilly and Company, Audion Therapeutics
    Inventors: Julia Marie Clay, Albert Edge, Philip Arthur Hipskind, John C. Gill, Bharvin Kumar Patel, Helmuth Hendrikus Gerardus Van Es, Aaron D. Wrobleski, Gaiying Zhao
  • NOTCH PATHWAY SIGNALING INHIBITOR COMPOUNDS
    Publication number: 20180148456
    Abstract: The present invention provides the following compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing said compounds useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing loss caused by auditory hair cell loss, and inducing auditory hair cell generation.
    Type: Application
    Filed: July 1, 2016
    Publication date: May 31, 2018
    Inventors: Julia Marie Clay, Albert Edge, Philip Arthur Hipskind, John C. Gill, Bharvin Kumar Patel, Helmuth Hendrikus Gerardus Van Es, Aaron D. Wrobleski, Gaiying Zhao
  • Pyrido[2,3-d]pyrimidin-4-one compounds as tankyrase inhibitors
    Patent number: 9624218
    Abstract: Pyrido[2,3-d]pyrimidin-4-one compounds, formulations containing those compounds, and their use as tankyrase 1 and 2 inhibitors Formula (I).
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: April 18, 2017
    Assignee: Eli Lilly and Company
    Inventors: Marcio Chedid, Hisham Omer Eissa, Thomas Albert Engler, Kelly Wayne Furness, Kenneth B. Rank, Timothy Andrew Woods, Aaron D. Wrobleski
  • PYRIDO[2,3-d]PYRIMIDIN-4-ONE COMPOUNDS AS TANKYRASE INHIBITORS
    Publication number: 20160251348
    Abstract: Pyrido[2,3-d]pyrimidin-4-one compounds, formulations containing those compounds, and their use as tankyrase 1 and 2 inhibitors Formula (I).
    Type: Application
    Filed: October 29, 2014
    Publication date: September 1, 2016
    Inventors: Marcio CHEDID, Hisham Omer EISSA, Thomas Albert ENGLER, Kelly Wayne FURNESS, Kenneth B. RANK, Timothy Andrew WOODS, Aaron D. WROBLESKI