Patents by Inventor Aaron David Gitler

Aaron David Gitler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12703722
    Abstract: Proteins and fusion proteins for forming membraneless droplets in cells are provided. Described herein, is the development of a protein, named PopTag, that drives phase separation when it is part of a chimeric fusion protein. PopTag is engineered from the PopZ protein, found in a-proteobacteria (including Caulobacter crescentus). Despite PopZ being exclusively found in this clade of bacteria, the PopTag can drive protein phase separation in other prokaryotes (e.g., E. coli) and eukaryotes (e.g., human cells).
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: August 11, 2026
    Assignees: CZ Biohub SF, LLC, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Keren Lasker, Steven Boeynaems, Aaron David Gitler, Lucy Shapiro
  • Publication number: 20230044825
    Abstract: Proteins and fusion proteins for forming merbraneless droplets in cells are provided. Described herein, is the development of a protein, named PopTag, that drives phase separation when it is part of a chimeric fusion protein. PopTag is engineered from the PopZ protein, found in a-proteobacteria (including Caulobacter crescentus). Despite PopZ being exclusively found in this clade of bacteria, the PopTag can drive protein phase separation in other prokaryotes (e.g., E. coli) and eukaryotes (e.g., human cells).
    Type: Application
    Filed: December 4, 2020
    Publication date: February 9, 2023
    Inventors: Keren Lasker, Steven Boeynaems, Aaron David Gitler, Lucy Shapiro