Patents by Inventor Aaron David Schimmer

Aaron David Schimmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR ENHANCING T CELLS USING VENETOCLAX
    Publication number: 20230059785
    Abstract: Methods of treating T cells with Venetoclax to increase T cell-mediated cytotoxicity and/or T cell mediated anti-tumor activity are described. Also described are populations of enhanced T cells as well as associated methods and uses for the treatment of cancer.
    Type: Application
    Filed: February 8, 2021
    Publication date: February 23, 2023
    Inventors: Li Zhang, Jongbok Lee, Aaron David Schimmer
  • AVOCADO-DERIVED LIPIDS FOR USE IN TREATING LEUKEMIA
    Publication number: 20170304251
    Abstract: A method of treating a leukemia comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising a compound of Formula (I) and/or (II) having the structure: OR2 R R1O n OR2 R R1O n I II wherein: 10 ---- represents a single or a double bond; R is OH when C----R is C—R, and R is O when C----R is C?R; n is 1, 3, 5 or 7; and R1 and R2 are independently hydrogen or acetyl, and/or isomers, stereoisomers or solvates thereof and/or mixtures thereof.
    Type: Application
    Filed: October 9, 2015
    Publication date: October 26, 2017
    Inventors: Paul Anthony SPAGNUOLO, Aaron David SCHIMMER
  • INHIBITING CYCLIN D POLYPEPTIDES
    Publication number: 20150004696
    Abstract: This document involves methods and materials related to inhibiting cyclin D polypeptide activity. For example, this document provides methods and materials that can be used to (1) identify mammals or cells in need of cyclin D polypeptide inhibition and (2) administer an agent capable of inhibiting cyclin D polypeptide activity.
    Type: Application
    Filed: July 25, 2014
    Publication date: January 1, 2015
    Inventors: Rodger E. Tiedemann, Alexander Keith Stewart, Aaron David Schimmer, Xinliang Mao
  • Inhibiting cyclin D polypeptides
    Patent number: 8822440
    Abstract: This document involves methods and materials related to inhibiting cyclin D polypeptide activity. For example, this document provides methods and materials that can be used to (1) identify mammals or cells in need of cyclin D polypeptide inhibition and (2) administer an agent capable of inhibiting cyclin D polypeptide activity.
    Type: Grant
    Filed: October 10, 2007
    Date of Patent: September 2, 2014
    Assignees: Mayo Foundation for Medical Education and Research, University Health Network
    Inventors: Rodger E. Tiedemann, Alexander Keith Stewart, Aaron David Schimmer, Xinliang Mao
  • Use of Synergistic Combinations of an Avermectin and an Antineoplastic Compounds for the Treatment of Hematological Malignancies
    Publication number: 20120225123
    Abstract: The disclosure relates to a method of treating a hematological malignancy comprising administering to a subject in need thereof a synergistic combination of a first compound comprising an effective amount of one or more Avermectins and a second compound comprising a chemotherapeutic, preferably daunorubicin, cyarabine, doxorubicin, idarubicin mitoxantrone, amsacrine, and mixtures thereof.
    Type: Application
    Filed: November 9, 2010
    Publication date: September 6, 2012
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Aaron David Schimmer, Sumaiya Sharmeen, Marko Skrtic
  • Use of Flubendazole and Vinca Alkaloids for Treatment of Hematological Diseases
    Publication number: 20120202840
    Abstract: Provided are methods for treating a hematological malignancy comprising administering an effective amount of flubendazole alone or in combination with a vinca alkaloid. Also provided are compositions and kits comprising an effective amount of flubendazole and/or a vinca alkaloid for use in the methods of the disclosure.
    Type: Application
    Filed: October 8, 2010
    Publication date: August 9, 2012
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Aaron David Schimmer, Jiayi Hu, Paul Anthony Spangnuolo
  • INHIBITING CYCLIN D POLYPEPTIDES
    Publication number: 20100144685
    Abstract: This document involves methods and materials related to inhibiting cyclin D polypeptide activity. For example, this document provides methods and materials that can be used to (1) identify mammals or cells in need of cyclin D polypeptide inhibition and (2) administer an agent capable of inhibiting cyclin D polypeptide activity.
    Type: Application
    Filed: October 10, 2007
    Publication date: June 10, 2010
    Inventors: Rodger E. Tiedemann, Alexander Keith Stewart, Aaron David Schimmer, Xinliang Mao