Abstract: Disclosed are compounds of Formula (I): or a pharmaceutically acceptable salt, a tautomer, a stereoisomer, or a deuterated analog thereof, wherein R1, R2, R3, R4, L and X are as described in any of the embodiments described in this disclosure; compositions thereof, and uses thereof.

Abstract: A fiber-reinforced polymer blade has a blade having at least a portion of itself including a fiber-reinforced polymer, a portion of the fiber-reinforced polymer including a chopped fiber-reinforced polymer. The invention further includes methods of manufacture of the blade.

Abstract: In an embodiment, an electronic device includes a display and processing circuitry. The display includes a plurality of pixels arranged in a plurality of rows, wherein a first grouping of the plurality of rows displays image content during a first portion of an image frame, and wherein a second grouping of the plurality of rows displays image content during a second portion of the image frame. The processing circuitry is operatively coupled to the display and determines a velocity associated with the image content displayed by the first grouping of the plurality of rows moving across the display and adjusts a position of the image content displayed by the second grouping of the plurality of rows during the second portion of the image frame.

Abstract: A method is provided for designing and producing fiber-reinforced polymer (FRP) pistons. Pistons made with FRP have a lower mass than prior art metal pistons conferring advantageous engine efficiency and stability. FRP pistons also increase the thermal efficiency of engines by having a lower thermal conductivity, with tighter piston-to-bore clearance, and/increased air-fuel ratio than pistons of metal. The technical parameters of the piston are identified, and a piston body blank is produced. The blank is then machined, a bearing surface for the pin bore is created, the piston blank is optionally coated, is optionally subjected to Heavy Metal Ion Implantation (HMII) treatment and is subjected to sodium silicate impregnation to produce the final pistons.

Abstract: A method is provided for designing and producing fiber-reinforced polymer (FRP) pistons. Pistons made with FRP have a lower mass than prior art metal pistons conferring advantageous engine efficiency and stability. FRP pistons also increase the thermal efficiency of engines by having a lower thermal conductivity, with tighter piston-to-bore clearance, and/increased air-fuel ratio than pistons of metal. The technical parameters of the piston are identified, and a piston body blank is produced. The blank is then machined, a bearing surface for the pin bore is created, the piston blank is optionally coated, is optionally subjected to Heavy Metal Ion Implantation (HMII) treatment and is subjected to sodium silicate impregnation to produce the final pistons.