Abstract: A pluggable implant is disclosed that is comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end, the cavity capable of accommodating a plug insertable from the distal end towards the apical end, such that when the plug is fully inserted and located in its apically-most position, the plug seals the cavity. Moreover, there is a method for plugging a hollow implant is disclosed, the implant comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end; wherein a plug is removably inserted into the implant through the cavity from the distal end towards the apical end such that when the plug is in fully inserted position and located in its apically-most position, the plug seals the cavity.

Abstract: A pluggable implant is disclosed that is comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end, the cavity capable of accommodating a plug insertable from the distal end towards the apical end, such that when the plug is fully inserted and located in its apically-most position, the plug seals the cavity. Moreover, there is a method for plugging a hollow implant is disclosed, the implant comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end; wherein a plug is removably inserted into the implant through the cavity from the distal end towards the apical end such that when the plug is in fully inserted position and located in its apically-most position, the plug seals the cavity.

Abstract: A set of distal femoral knee prostheses which are designed to be more narrow in medial/lateral dimensions with increasing anterior/posterior size than existing prostheses to more closely correspond to the physical anatomy of female patients. The prostheses are designed to have a substantially trapezoidal shape or profile when viewed distally which features a more pronounced narrowing of the medial/lateral dimensions beginning at the posterior end of the prostheses and progressing anteriorly to the anterior end of the prostheses. Additionally, the prostheses each include a reduced profile patellar sulcus and reduced profile anterior condyles to more closely conform to the anatomy of a resected femur, and also include sulcus tracking optimized to conform to female anatomy.

Abstract: A peri-arterial blood flow booster apparatus for improving blood pressure and flow, to be implanted around a blood vessel of a patient. The booster comprises a pressure applying device (56) comprising at least one balloon (44), placed alongside a portion of the blood vessel and a restrainer (54) for restraining the balloon and providing counter-forces. It further comprises a control console (60) comprising: an inflating unit (66) for rapidly inflating and deflating the balloon, the inflating unit connected to the balloon; sensing means (68) for sensing electrocardiograph signals of the patient; a control unit (72) for controlling the operation of the inflating unit correlating to the electrocardiograph signals detected by the sensing means. When the balloon is inflated the restrainer forces it to compress the portion of the blood vessel preventing backflow and exerting forces on the blood vessel forcing blood within the portion of the blood vessel to flow antegradely.

Abstract: A peri-arterial blood flow booster apparatus for improving blood pressure and flow, to be implanted around a blood vessel of a patient. The booster comprises a pressure applying device (56) comprising at least one balloon (44), placed alongside a portion of the blood vessel and a restrainer (54) for restraining the balloon and providing counter-forces. It further comprises a control console (60) comprising: an inflating unit (66) for rapidly inflating and deflating the balloon, the inflating unit connected to the balloon; sensing means (68) for sensing electrocardiograph signals of the patient; a control unit (72) for controlling the operation of the inflating unit correlating to the electrocardiograph signals detected by the sensing means. When the balloon is inflated the restrainer forces it to compress the portion of the blood vessel preventing backflow and exerting forces on the blood vessel forcing blood within the portion of the blood vessel to flow antegradely.

Abstract: A set of distal femoral knee prostheses which are designed to be more narrow in medial/lateral dimensions with increasing anterior/posterior size than existing prostheses to more closely correspond to the physical anatomy of female patients. The prostheses are designed to have a substantially trapezoidal shape or profile when viewed distally which features a more pronounced narrowing of the medial/lateral dimensions beginning at the posterior end of the prostheses and progressing anteriorly to the anterior end of the prostheses. Additionally, the prostheses each include a reduced profile patellar sulcus and reduced profile anterior condyles to more closely conform to the anatomy of a resected femur, and also include sulcus tracking optimized to conform to female anatomy.

Abstract: Methods for screening compounds for their solubility and their solution stability in a variety of diverse formulations and sets of diverse formulations useful for screening compounds for their solubility and their solution stability.

Abstract: A peri-arterial blood flow booster apparatus for improving blood pressure and flow, to be implanted around a blood vessel of a patient. The booster comprises a pressure applying device (56) comprising at least one balloon (44), placed alongside a portion of the blood vessel and a restrainer (54) for restraining the balloon and providing counter-forces. It further comprises a control console (60) comprising: an inflating unit (66) for rapidly inflating and deflating the balloon, the inflating unit connected to the balloon; sensing means (68) for sensing electrocardiograph signals of the patient; a control unit (72) for controlling the operation of the inflating unit correlating to the electrocardiograph signals detected by the sensing means. When the balloon is inflated the restrainer forces it to compress the portion of the blood vessel preventing backflow and exerting forces on the blood vessel forcing blood within the portion of the blood vessel to flow antegradely.

Abstract: In one aspect, the present invention provides sets of crystallization solutions that each include one of Crystallization Solution Set 1, Crystallization Solution Set 2, Crystallization Solution Set 3, and Crystallization Solution Set 4. In another aspect, the present invention provides kits that each include at least one crystallization plate and a Crystallization Solution Set of the invention.