Patents by Inventor Aaron J. Fleischman

Aaron J. Fleischman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7878208
    Abstract: Methods and systems are provided for determining a characteristic of an in vivo sensor. A transmit field, operative to induce a response signal in an associated in vivo sensor, is generated at a transmitting component having an associated orientation. The response signal is received at a receiving component, having an associated orientation. The coupling between the transmitting component and the receiving component is measured. The associated orientation of at least one of the transmitting component and the receiving component is rotated as to reduce the measured coupling.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: February 1, 2011
    Assignee: The Cleveland Clinic Foundation
    Inventors: James R. Talman, Shuvo Roy, Brian L. Sauer, Aaron J. Fleischman
  • Patent number: 7771351
    Abstract: Systems and methods are provided for determining a characteristic of an associated in vivo sensor within a living body. A transmit coil produces an excitation signal, having a first orientation, to excite the in vivo sensor to produce a response signal. A receive coil produces a current in response to the response signal. The receive coil is oriented to interact with signals having a second orientation that is substantially orthogonal to first orientation. The probe further comprises at least one eddy current compensation coil that produces a compensation field. A component of the compensation field along the second orientation has a magnitude at the receive coil substantially equal and opposite to a magnitude of a similarly oriented component of a magnetic field associated with eddy currents induced within the body.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: August 10, 2010
    Assignee: The Cleveland Clinic Foundation
    Inventors: James R. Talman, Aaron J. Fleischman, Brian L. Sauer, Shuvo Roy
  • Patent number: 7491179
    Abstract: An apparatus (10) that utilizes microelectromechanical systems (MEMS) technology to provide an in vivo assessment of loads on adjacent bones (24 and 26) comprises a body (34) for insertion between the adjacent bones. At least one sensor (42) is associated with the body (34). The sensor (42) generates an output signal in response to and indicative of a load being applied to the body (34) through the adjacent bones (24 and 26). A telemetric device (40) is operatively coupled with the sensor (42). The telemetric device (40) is operable to receive the output signal from the sensor (42) and to transmit an EMF signal dependent upon the output signal. According to various aspects of the invention, the sensor comprises a pressure sensor (42), a load cell (320), and/or at least one strain gauge (142).
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: February 17, 2009
    Assignee: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Aaron J Fleischman, Edward C. Benzel, Lisa Ferrara
  • Patent number: 7284442
    Abstract: Systems and methods for in vivo sensing are provided. An excitation signal is produced, having a first frequency component and a second frequency component. The first frequency component is swept through a plurality of excitation frequencies within a frequency range of interest. A response signal is received from an in vivo sensor. The response signal includes a mix component having a frequency equal to one of a sum of a first excitation frequency associated with the first frequency component and a second excitation frequency associated with the second frequency component and a difference between the first and second excitation frequencies. The mix component is evaluated to determine a resonant frequency of the in vivo sensor.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: October 23, 2007
    Assignee: The Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, James R. Talman, Shuvo Roy
  • Patent number: 7262068
    Abstract: A microneedle array module is disclosed comprising a multiplicity of microneedles affixed to and protruding outwardly from a front surface of a substrate to form the array, each microneedle of the array having a hollow section which extends through its center to an opening in the tip thereof. A method of fabricating the microneedle array module is also disclosed comprising the steps of: providing etch resistant mask layers to one and another opposite surfaces of a substrate to predetermined thicknesses; patterning the etch resistant mask layer of the one surface for outer dimensions of the microneedles of the array; patterning the etch resistant mask layer of the other surface for inner dimensions of the microneedles of the array; etching unmasked portions of the substrate from one and the other surfaces to first and second predetermined depths, respectively; and removing the mask layers from the one and the other surfaces.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: August 28, 2007
    Assignee: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Aaron J. Fleischman
  • Patent number: 7182736
    Abstract: An apparatus (10) that utilizes microelectromechanical systems (MEMS) technology to provide an in vivo assessment of loads on adjacent bones (24 and 26) comprises a body (34) for insertion between the adjacent bones. At least one sensor (42) is associated with the body (34). The sensor (42) generates an output signal in response to and indicative of a load being applied to the body (34) through the adjacent bones (24 and 26). A telemetric device (40) is operatively coupled with the sensor (42). The telemetric device (40) is operable to receive the output signal from the sensor (42) and to transmit an EMF signal dependent upon the output signal. According to various aspects of the invention, the sensor comprises a pressure sensor (42), a load cell (320), and/or at least one strain gauge (142).
    Type: Grant
    Filed: February 2, 2004
    Date of Patent: February 27, 2007
    Assignee: Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Aaron J. Fleischman, Edward C. Benzel, Lisa Ferrara
  • Patent number: 7169106
    Abstract: An apparatus (180) for measuring intraocular pressure (IOP) comprises a contact lens (40) including an inner surface (42) contoured to a surface portion (34) of an eye (36) and a sensor (10) disposed in the contact lens. The sensor (10) comprises a contact surface (14) for making contact with the surface portion (34) of the eye (36). The contact surface (14) includes an outer non-compliant region (16) and an inner compliant region (18) fabricated as an impedance element that varies in impedance as the inner compliant region changes shape. The sensor (10) further comprises a region of conductive material (38) electrically coupled to the impedance element of the compliant region (18) and responsive to an external signal for energizing the impedance element so that the IOP may be determined.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: January 30, 2007
    Assignee: The Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy, Hilel Lewis
  • Patent number: 6994672
    Abstract: An apparatus (176) for measuring intraocular pressure (IOP) comprises an applanation tonometer (180) having a distal end that is movable toward the eye and a disposable module (188) positioned at the distal end. The module (188) includes a sensor carrier (192) and a sensor (10) connected to the sensor carrier. The sensor (10) comprises a contact surface (14) for making contact with a surface portion of the eye (36). The contact surface (14) includes an outer non-compliant region (16) and an inner compliant region (18) fabricated as an impedance element that varies in impedance as the inner compliant region changes shape. The sensor (10) further comprises a region of conductive material (38) electrically coupled to the impedance element of the compliant region (18) and responsive to an external signal for energizing the impedance element so that the IOP may be determined.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: February 7, 2006
    Assignee: Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy
  • Publication number: 20040243063
    Abstract: A microneedle array module is disclosed comprising a multiplicity of microneedles affixed to and protruding outwardly from a front surface of a substrate to form the array, each microneedle of the array having a hollow section which extends through its center to an opening in the tip thereof. A method of fabricating the microneedle array module is also disclosed comprising the steps of: providing etch resistant mask layers to one and another opposite surfaces of a substrate to predetermined thicknesses; patterning the etch resistant mask layer of the one surface for outer dimensions of the microneedles of the array; patterning the etch resistant mask layer of the other surface for inner dimensions of the microneedles of the array; etching unmasked portions of the substrate from one and the other surfaces to first and second predetermined depths, respectively; and removing the mask layers from the one and the other surfaces.
    Type: Application
    Filed: July 6, 2004
    Publication date: December 2, 2004
    Applicant: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Aaron J. Fleischman
  • Publication number: 20040207808
    Abstract: An apparatus (180) for measuring intraocular pressure (IOP) comprises a contact lens (40) including an inner surface (42) contoured to a surface portion (34) of an eye (36) and a sensor (10) disposed in the contact lens. The sensor (10) comprises a contact surface (14) for making contact with the surface portion (34) of the eye (36). The contact surface (14) includes an outer non-compliant region (16) and an inner compliant region (18) fabricated as an impedance element that varies in impedance as the inner compliant region changes shape. The sensor (10) further comprises a region of conductive material (38) electrically coupled to the impedance element of the compliant region (18) and responsive to an external signal for energizing the impedance element so that the IOP may be determined.
    Type: Application
    Filed: May 7, 2004
    Publication date: October 21, 2004
    Applicant: The Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy, Hilel Lewis
  • Publication number: 20040186396
    Abstract: An apparatus (10) that utilizes microelectromechanical systems (MEMS) technology to provide an in vivo assessment of loads on adjacent bones (24 and 26) comprises a body (34) for insertion between the adjacent bones. At least one sensor (42) is associated with the body (34). The sensor (42) generates an output signal in response to and indicative of a load being applied to the body (34) through the adjacent bones (24 and 26). A telemetric device (40) is operatively coupled with the sensor (42). The telemetric device (40) is operable to receive the output signal from the sensor (42) and to transmit an EMF signal dependent upon the output signal. According to various aspects of the invention, the sensor comprises a pressure sensor (42), a load cell (320), and/or at least one strain gauge (142).
    Type: Application
    Filed: February 2, 2004
    Publication date: September 23, 2004
    Applicant: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Aaron J. Fleischman, Edward C. Benzel, Lisa Ferrara
  • Patent number: 6790372
    Abstract: A microneedle array module is disclosed comprising a multiplicity of microneedles affixed to and protruding outwardly from a front surface of a substrate to form the array, each microneedle of the array having a hollow section which extends through its center to an opening in the tip thereof. A method of fabricating the microneedle array module is also disclosed comprising the steps of: providing etch resistant mask layers to one and another opposite surfaces of a substrate to predetermined thicknesses; patterning the etch resistant mask layer of the one surface for outer dimensions of the microneedles of the array; patterning the etch resistant mask layer of the other surface for inner dimensions of the microneedles of the array; etching unmasked portions of the substrate from one and the other surfaces to first and second predetermined depths, respectively; and removing the mask layers from the one and the other surfaces.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: September 14, 2004
    Assignee: Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Aaron J. Fleischman
  • Patent number: 6749568
    Abstract: An apparatus for measuring intraocular pressure (IOP) comprises a contact lens including an inner surface contoured to a surface portion of an eye and a sensor disposed in the contact lens. The sensor comprises a contact surface for making contact with the surface portion of the eye. The contact surface includes an outer non-compliant region and an inner compliant region fabricated as an impedance element that varies in impedance as the inner compliant region changes shape. The sensor further comprises a region of conductive material electrically coupled to the impedance element of the compliant region and responsive to an external signal for energizing the impedance element so that the IOP may be determined.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: June 15, 2004
    Assignee: Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy, Hilel Lewis
  • Patent number: 6706005
    Abstract: An apparatus (10) that utilizes microelectromechanical systems (MEMS) technology to provide an in vivo assessment of loads on adjacent bones (24 and 26) comprises a body (34) for insertion between the adjacent bones. At least one sensor (42) is associated with the body (34). The sensor (42) generates an output signal in response to and indicative of a load being applied to the body (34) through the adjacent bones (24 and 26). A telemetric device (40) is operatively coupled with the sensor (42). The telemetric device (40) is operable to receive the output signal from the sensor (42) and to transmit an EMF signal dependent upon the output signal. According to various aspects of the invention, the sensor comprises a pressure sensor (42), a load cell (320), and/or at least one strain gauge (142).
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: March 16, 2004
    Assignee: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Aaron J. Fleischman, Edward C. Benzel, Lisa Ferrara
  • Patent number: 6682490
    Abstract: An apparatus (10) utilizes microelectricalmechanical systems (MEMS) technology to monitor a condition in a body cavity (28). The apparatus (10) comprises at least one sensor (42) for insertion into the body cavity. The sensor (42) generates a signal in response to a condition inside the body cavity (28). At least one telemetric device (44) is operatively coupled with the sensor (42). The telemetric device (44) is operable to receive the signal from the sensor (42) and to transmit an electromagnetic signal dependent upon the signal. The telemetric device (44) includes at least one coil member (82) extending from the telemetric device. The coil member (82) engages the body cavity (28) to secure the telemetric device (44) in the body cavity.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: January 27, 2004
    Assignee: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Kenneth Ouriel, Aaron J. Fleischman
  • Patent number: 6641540
    Abstract: An ultrasonic transducer (108) for use in medical imaging comprises a substrate (300) having first and second surfaces. The substrate (300) includes an aperture (301) extending from the first surface to the second surface. Electronic circuitry (302) is located on the first surface. A diaphragm (304) is positioned at least partially within the aperture (301) and in electrical communication with the electronic circuitry (302). The diaphragm (304) has an arcuate shape, formed by applying a differential pressure, that is a section of a sphere. A binder material (314) is in physical communication with the diaphragm (304) and the substrate (300).
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: November 4, 2003
    Assignee: The Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy, Geoffrey R. Lockwood
  • Patent number: 6623984
    Abstract: The present invention provides a MEMS-based integrated particle identification system having a substrate, a magnetic structure, and a bioferrograph. The substrate includes a topside portion, backside portion and a flow system. The flow system includes a flow channel for accepting the flow of a stream of particles to identified. The magnetic structure is in physical communication with the topside and backside portions of the substrate and has at least two pole pieces. A plurality of pole piece embodiments are provided for generating a magnetic field that acts on magnetically susceptible particles in the flow stream. The bioferrograph has at least one sensor for identifying the presence and quantity of magnetically susceptible particles. A plurality of sensor embodiments are also provided.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: September 23, 2003
    Assignee: The Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy, Jeff Chalmers, Maciej Zborowski
  • Publication number: 20030105388
    Abstract: An apparatus (10) utilizes microelectricalmechanical systems (MEMS) technology to monitor a condition in a body cavity (28). The apparatus (10) comprises at least one sensor (42) for insertion into the body cavity. The sensor (42) generates a signal in response to a condition inside the body cavity (28). At least one telemetric device (44) is operatively coupled with the sensor (42). The telemetric device (44) is operable to receive the signal from the sensor (42) and to transmit an electromagnetic signal dependent upon the signal. The telemetric device (44) includes at least one coil member (82) extending from the telemetric device. The coil member (82) engages the body cavity (28) to secure the telemetric device (44) in the body cavity.
    Type: Application
    Filed: December 3, 2001
    Publication date: June 5, 2003
    Applicant: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Kenneth Ouriel, Aaron J. Fleischman
  • Publication number: 20020193674
    Abstract: An apparatus (180) for measuring intraocular pressure (IOP) comprises a contact lens (40) including an inner surface (42) contoured to a surface portion (34) of an eye (36) and a sensor (10) disposed in the contact lens. The sensor (10) comprises a contact surface (14) for making contact with the surface portion (34) of the eye (36). The contact surface (14) includes an outer non-compliant region (16) and an inner compliant region (18) fabricated as an impedance element that varies in impedance as the inner compliant region changes shape. The sensor (10) further comprises a region of conductive material (38) electrically coupled to the impedance element of the compliant region (18) and responsive to an external signal for energizing the impedance element so that the IOP may be determined.
    Type: Application
    Filed: April 22, 2002
    Publication date: December 19, 2002
    Applicant: The Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy, Hilel Lewis
  • Publication number: 20020177768
    Abstract: An apparatus (176) for measuring intraocular pressure (IOP) comprises an applanation tonometer (180) having a distal end that is movable toward the eye and a disposable module (188) positioned at the distal end. The module (188) includes a sensor carrier (192) and a sensor (10) connected to the sensor carrier. The sensor (10) comprises a contact surface (14) for making contact with a surface portion of the eye (36). The contact surface (14) includes an outer non-compliant region (16) and an inner compliant region (18) fabricated as an impedance element that varies in impedance as the inner compliant region changes shape. The sensor (10) further comprises a region of conductive material (38) electrically coupled to the impedance element of the compliant region (18) and responsive to an external signal for energizing the impedance element so that the IOP may be determined.
    Type: Application
    Filed: April 8, 2002
    Publication date: November 28, 2002
    Applicant: The Cleveland Clinic Foundation
    Inventors: Aaron J. Fleischman, Shuvo Roy