Patents by Inventor Aaron J. Tooley

Aaron J. Tooley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineering of living cells for the expression of holo-phycobiliprotein-based constructs
    Patent number: 6740507
    Abstract: Recombinant cells which express a fluorescent holo-phycobiliprotein fusion protein and methods of use are described. The cells comprises a bilin, a recombinant bilin reductase, an apo-phycobiliprotein fusion protein precursor of the fusion protein comprising a corresponding apo-phycobiliprotein domain, and a recombinant phycobiliprotein domain-bilin lyase, which components react to form the holo-phycobiliprotein fusion protein. Also described are holo-phycobiliprotein based transcription reporter cells and assays, which cells conditionally express a heterologous-to-the-cell, fluorescent, first holo-phycobiliprotein domain.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: May 25, 2004
    Assignee: The Regents of the University of California
    Inventors: Alexander N. Glazer, Aaron J. Tooley, Yuping Cai
  • Engineering of living cells for the expression of holo-phycobiliprotein-based constructs
    Publication number: 20030027285
    Abstract: Recombinant cells which express a fluorescent holo-phycobiliprotein fusion protein and methods of use are described. The cells comprises a bilin, a recombinant bilin reductase, an apo-phycobiliprotein fusion protein precursor of the fusion protein comprising a corresponding apo-phycobiliprotein domain, and a recombinant phycobiliprotein domain-bilin lyase, which components react to form the holo-phycobiliprotein fusion protein. Also described are holo-phycobiliprotein based transcription reporter cells and assays, which cells conditionally express a heterologous-to-the-cell, fluorescent, first holo-phycobiliprotein domain.
    Type: Application
    Filed: July 31, 2001
    Publication date: February 6, 2003
    Inventors: Alexander N. Glazer, Aaron J. Tooley, Yuping Cai