Patents by Inventor Aaron MICHELS

Aaron MICHELS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180335431
    Abstract: The invention includes methods and kits that can be used to simultaneously determine whether an antibody out of a plurality of antibodies is present in a sample. In certain embodiments, at least one of the antibodies comprises an autoantibody. In other embodiments, the methods and kits of the invention can be used to simultaneously determine if a subject is likely to develop or has developed each one of a plurality of diseases or disorders.
    Type: Application
    Filed: November 17, 2016
    Publication date: November 22, 2018
    Inventors: LIPING YU, MARIAN REWERS, AARON MICHELS
  • Publication number: 20180117124
    Abstract: Methods for inhibiting an autoimmune disease by administering to a subject a therapeutically effective amount of a composition that induces conversion of naive T cells into Foxp3+ regulatory T cells to induce immunosuppression in the subject. Methods for detecting in a subject an autoimmune disease or a predisposition to an autoimmune disease, and methods for assessing the efficacy of a therapy for an autoimmune disease, particularly type 1 diabetes.
    Type: Application
    Filed: January 13, 2016
    Publication date: May 3, 2018
    Inventors: Aaron MICHELS, John KAPPLER, Peter A. GOTTLIEB
  • Publication number: 20180116988
    Abstract: Methods of preventing, treating or ameliorating autoimmune diabetes by modulating the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease by the administration of methyldopa. Pharmaceutical compositions containing therapeutically effective amounts of methyldopa in extended release formulations and methods of using the same are also provided.
    Type: Application
    Filed: May 27, 2016
    Publication date: May 3, 2018
    Inventors: Thomas J. ANCHORDOQUY, Peter A. GOTTLIEB, Aaron MICHELS, David OSTROV
  • Publication number: 20120225813
    Abstract: Embodiments herein concern compositions and methods for treating diabetes in a subject.
    Type: Application
    Filed: June 13, 2011
    Publication date: September 6, 2012
    Inventors: Eli C. LEWIS, Peter GOTTLIEB, Charles A. DINARELLO, Leland SHAPIRO, Aaron MICHELS
  • Publication number: 20110112017
    Abstract: Embodiments herein concern compositions and methods for treating diabetes in a subject.
    Type: Application
    Filed: June 11, 2010
    Publication date: May 12, 2011
    Inventors: Lee SHAPIRO, Charles A. DINARELLO, Eli LEWIS, Peter GOTTLIEB, Amy WALLACE, Aaron MICHELS, Gregory B. POTTS