Patents by Inventor Aaron Ohta
Aaron Ohta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10105712Abstract: An optical pattern-driven light induced dielectrophoresis (DEP) apparatus and separation methods are described which provide for the manipulation of particles or cells and selection based on traits correlated with the DEP response. Embodiments of the apparatus use DEP electric field patterns in combination with microfluidic laminar flows to measure response, separate, segregate and extract particles from heterogeneous mixtures according to the relative response of the particles to one or more DEP fields without damaging living cells. The preferred OET-DEP devices generally comprise a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a localized virtual electrode with a DEP electric field gradient of selected intensity along with input and a plurality of output fluidic channels. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or groups of particles/cells.Type: GrantFiled: June 18, 2015Date of Patent: October 23, 2018Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Maurice M. Garcia, Aaron Ohta, Ming Wu, Tom F. Lue, Justin Valley
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Publication number: 20150360236Abstract: An optical pattern-driven light induced dielectrophoresis (DEP) apparatus and separation methods are described which provide for the manipulation of particles or cells and selection based on traits correlated with the DEP response. Embodiments of the apparatus use DEP electric field patterns in combination with microfluidic laminar flows to measure response, separate, segregate and extract particles from heterogeneous mixtures according to the relative response of the particles to one or more DEP fields without damaging living cells. The preferred OET-DEP devices generally comprise a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a localized virtual electrode with a DEP electric field gradient of selected intensity along with input and a plurality of output fluidic channels. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or groups of particles/cells.Type: ApplicationFiled: June 18, 2015Publication date: December 17, 2015Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Maurice M. Garcia, Aaron Ohta, Ming Wu, Tom F. Lue, Justin Valley
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Patent number: 9079189Abstract: An optical pattern-driven light induced dielectrophoresis (DEP) apparatus and separation methods are described which provide for the manipulation of particles or cells and selection based on traits correlated with the DEP response. Embodiments of the apparatus use DEP electric field patterns in combination with microfluidic laminar flows to measure response, separate, segregate and extract particles from heterogeneous mixtures according to the relative response of the particles to one or more DEP fields without damaging living cells. The methods are particularly suited for selecting and extracting the best sperm and embryo candidates based on fitness for use with existing artificial reproduction procedures and excluding defective or non-viable gametes.Type: GrantFiled: September 30, 2011Date of Patent: July 14, 2015Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Maurice M. Garcia, Aaron Ohta, Ming Wu, Tom F. Lue, Justin Valley
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Publication number: 20120118740Abstract: An optical pattern-driven light induced dielectrophoresis (DEP) apparatus and separation methods are described which provide for the manipulation of particles or cells and selection based on traits correlated with the DEP response. Embodiments of the apparatus use DEP electric field patterns in combination with microfluidic laminar flows to measure response, separate, segregate and extract particles from heterogeneous mixtures according to the relative response of the particles to one or more DEP fields without damaging living cells. The methods are particularly suited for selecting and extracting the best sperm and embryo candidates based on fitness for use with existing artificial reproduction procedures and excluding defective or non-viable gametes.Type: ApplicationFiled: September 30, 2011Publication date: May 17, 2012Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Maurice M. Garcia, Aaron Ohta, Ming Wu, Tom F. Lue, Justin Valley
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Publication number: 20110223314Abstract: A device and method for generating microcapsules employs an inertial-focusing channel for introducing particles dispersed in a prepolymer suspension fluid, a droplet-generating junction for introducing oil evenly onto the flow of particles to create separated droplets of prepolymer suspension fluid encapsulating respective particles in a streamline flow, and a polymerization section for exposing the droplets to UV light or heat to cause polymerization of a polymer coating on separate microcapsules each containing a respective particle. Preferred suspension fluids may be aqueous solution of poly(ethylene-glycol)-diacrylate (PEGDA), or poly(N-isopropyl-acryalmide) (PNIPAAM). The preferred device may employ a curved or linear inertial-focusing microchannel. Functional tags and/or handles may be added to the microcapsules allowing easy detection, measurement and handling of the microcapsules.Type: ApplicationFiled: March 10, 2011Publication date: September 15, 2011Inventors: Xiaoxiao ZHANG, David Garmire, Aaron Ohta
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Patent number: 7956339Abstract: Described herein are single-sided lateral-field optoelectronic tweezers (LOET) devices which use photosensitive electrode arrays to create optically-induced dielectrophoretic forces in an electric field that is parallel to the plane of the device. In addition, phototransistor-based optoelectronic tweezers (PhOET) devices are described that allow for optoelectronic tweezers (OET) operation in high-conductivity physiological buffer and cell culture media.Type: GrantFiled: September 24, 2009Date of Patent: June 7, 2011Assignee: The Regents of the University of CaliforniaInventors: Aaron Ohta, Pei-Yu Chiou, Hsan-Yin Hsu, Arash Jamshidi, Ming-Chiang Wu, Steven L. Neale
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Publication number: 20100101960Abstract: Described herein are single-sided lateral-field optoelectronic tweezers (LOET) devices which use photosensitive electrode arrays to create optically-induced dielectrophoretic forces in an electric field that is parallel to the plane of the device. In addition, phototransistor-based optoelectronic tweezers (PhOET) devices are described that allow for optoelectronic tweezers (OET) operation in high-conductivity physiological buffer and cell culture media.Type: ApplicationFiled: September 24, 2009Publication date: April 29, 2010Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Aaron Ohta, Pei-Yu Chiou, Hsan-Yin Hsu, Arash Jamshidi, Ming-Chiang Wu, Steven L. Neale
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Patent number: 7304607Abstract: A high-directivity transponder system uses a dual system of a retrodirective array transmitting a data signal peak toward an interrogator source, and a self-null-steering array transmitting a null toward the interrogator source and a jamming signal elsewhere, resulting in high S/N reception at the interrogator source and avoidance of interception. Integrating modulators would allow each array to transmit different data while the spectra of the transmitted signals are identical, thus disabling interception. The system enables secure point-to-point communications and can be used for short-distance wireless data transmission systems such as wireless LAN and RFID servers.Type: GrantFiled: December 6, 2005Date of Patent: December 4, 2007Assignee: University of Hawai'iInventors: Ryan Y. Miyamoto, Wayne A. Shiroma, Grant S. Shiroma, Blaine T. Murakami, Aaron Ohta, Michael Tamamoto
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Publication number: 20060238414Abstract: A high-directivity transponder system uses a dual system of a retrodirective array transmitting a data signal peak toward an interrogator source, and a self-null-steering array transmitting a null toward the interrogator source and a jamming signal elsewhere, resulting in high S/N reception at the interrogator source and avoidance of interception. Integrating modulators would allow each array to transmit different data while the spectra of the transmitted signals are identical, thus disabling interception. The system enables secure point-to-point communications and can be used for short-distance wireless data transmission systems such as wireless LAN and RFID servers. As another aspect, self-steering signal transmission is employed for randomly oriented satellites using circularly polarized, two-dimensional retrodirective arrays. Quadruple subharmonic mixing is used as an effective means of achieving phase conjugation when a high-frequency LO is not feasible or inapplicable.Type: ApplicationFiled: December 6, 2005Publication date: October 26, 2006Inventors: Ryan Miyamoto, Wayne Shiroma, Grant Shiroma, Blaine Murakami, Aaron Ohta, Michael Tamamoto
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Patent number: 7006039Abstract: A high-directivity transponder system uses a dual system of a retrodirective array transmitting a data signal peak toward an interrogator source, and a self-null-steering array transmitting a null toward the interrogator source and a jamming signal elsewhere, resulting in high S/N reception at the interrogator source and avoidance of interception. Integrating modulators would allow each array to transmit different data while the spectra of the transmitted signals are identical, thus disabling interception. The system enables secure point-to-point communications and can be used for short-distance wireless data transmission systems such as wireless LAN and RFID servers. As another aspect, self-steering signal transmission is employed for randomly oriented satellites using circularly polarized, two-dimensional retrodirective arrays. Quadruple subharmonic mixing is used as an effective means of achieving phase conjugation when a high-frequency LO is not feasible or inapplicable.Type: GrantFiled: August 4, 2004Date of Patent: February 28, 2006Assignee: University of HawaiiInventors: Ryan Y. Miyamoto, Wayne A. Shiroma, Grant S. Shiroma, Blaine T. Murakami, Aaron Ohta, Michael Tamamoto
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Publication number: 20050030226Abstract: A high-directivity transponder system uses a dual system of a retrodirective array transmitting a data signal peak toward an interrogator source, and a self-null-steering array transmitting a null toward the interrogator source and a jamming signal elsewhere, resulting in high S/N reception at the interrogator source and avoidance of interception. Integrating modulators would allow each array to transmit different data while the spectra of the transmitted signals are identical, thus disabling interception. The system enables secure point-to-point communications and can be used for short-distance wireless data transmission systems such as wireless LAN and RFID servers. As another aspect, self-steering signal transmission is employed for randomly oriented satellites using circularly polarized, two-dimensional retrodirective arrays. Quadruple subharmonic mixing is used as an effective means of achieving phase conjugation when a high-frequency LO is not feasible or inapplicable.Type: ApplicationFiled: August 4, 2004Publication date: February 10, 2005Inventors: Ryan Miyamoto, Wayne Shiroma, Grant Shiroma, Blaine Murakami, Aaron Ohta, Michael Tamamoto