Abstract: An electronic device displays a first icon comprising a shape. While displaying the first icon, the device receives a voice command corresponding to a request for media content from the application. In response to, and while receiving, the voice command, the device dynamically animates the first icon, including distorting a radius of a portion of the shape in accordance with a direction of the voice command. The dynamic animation indicates that the electronic device is in a first state. After the voice command is completed, the device displays an indication that the device is in a second state that is distinct from the first state.

Abstract: A controller for a plasma generation system includes a model evaluation module receives a sensed value that varies in accordance with a state of a plasma controlled by a RF power generator. The model evaluation module generates a plasma parameter that varies in accordance with the sensed value. A model integration module receives the plasma parameter, integrates the plasma parameter, and outputs an integrated model parameter. An IEDF evaluation module receives the integrated model parameter and generates an ion energy distribution function (IEDF) in accordance with the integrated model parameter. An IEDF controller module receives the IEDF and generates a signal for controlling a RF generator. A RF generator control module receives the signal and generates an RF generator control signal to control at least one of power, frequency, or phase of the RF power generator.

Abstract: A cargo restraint system comprises a plurality of cargo restraint assemblies. Each cargo restraint assembly in the plurality of cargo restraint assemblies may be removably coupled to a cargo deck in various configurations. The plurality of cargo restraint assemblies may be reconfigurable based on a size of a plurality of unit load devices (ULDs) to be loaded and restrained. Each cargo restraint assembly may restrain four or fewer corners of respective ULDs simultaneously.

Abstract: A flexure having six degrees of freedom is disclosed. The constraint and compliance of the flexure in all six degrees of freedom may be independently tuned for an application. The flexure may include various combinations of sections including, for example, straight arm and curvilinear sections. The constraint and compliance of the flexure is determined by the geometry, cross-sectional area, cross-sectional shape, and material used to form the various sections. A coupling mechanism and a corresponding method for using the coupling mechanism for automated or autonomous assembly of elements using tuned flexures is disclosed. The automated or autonomous assembly of elements employs a coupling mechanism having a motor driven grip and a coupler, in which the coupler includes a six degrees of freedom flexure. The motor driven grip and coupler may optionally include electrical or optical interconnections and self-aligning features.

Abstract: A power system includes a battery and a controller. The controller inhibits charge of the battery according to voltage or current values sensed before and after contactors electrically connected to the battery are commanded to open and indicating that a leakage resistance associated with one of the contactors increases after the one of contactors is commanded to open, and a duration of a continuous voltage drop across another of the contactors after the another of the contactors is commanded to open exceeds a threshold.

Abstract: Instruments, methods, and kits are disclosed for performing fast thermocycling.

Abstract: A portable steam generator includes a power source in a housing, a water tank in the housing, a heating element in the housing and configured to heat water in the water tank to produce steam using power from the power source, and a track on the housing configured to support the portable steam generator in an installation position and allow manual removal from the installation position. A pre-plumbed integrated bathroom panel includes a plumbing inlet configured to provide water to the panel, a water outlet connected to the plumbing inlet, a steam outlet connected to the plumbing inlet and a heating element, a sanitizing outlet connected to the plumbing inlet and an additive generator, valves for directing water from the plumbing inlet to the at least one water outlet, the at least one steam outlet, and the at least one sanitizing outlet, and a controller configured to operate at least the plurality of valves.

Abstract: Behavioral and mental health therapy systems in accordance with several embodiments of the invention include a wearable camera and/or a variety of sensors (accelerometer, microphone, among various other) connected to a computing system including a display, audio output, holographic output, and/or vibrotactile output to automatically recognize social cues from images captured by at least one camera and provide this information to the wearer via one or more outputs such as (but not limited to) displaying an image, displaying a holographic overlay, generating an audible signal, and/or generating a vibration.

Abstract: In various embodiments method are provided for generating expression cassettes and gene therapy vectors comprising those cassettes that recapitulate the spatiotemporal pattern of expression of the endogenous gene. In certain embodiments the methods comprise (i) selecting a target gene; (ii) identifying putative regulatory elements associated with the target gene; (iii) determining if the regulatory element is a key regulatory element and (iv) providing a list of the key regulatory elements identified in step (iii).

Abstract: A system and method for updating power supply voltages due to variations from aging are described. A functional unit includes a power supply monitor capable of measuring power supply variations in a region of the functional unit. An age counter measures an age of the functional unit. A control unit notifies the power supply monitor to measure an operating voltage reference. When the control unit receives a measured operating voltage reference, the control unit determines an updated age of the region different from the current age based on the measured operating voltage reference. The control unit updates the age counter with the corresponding age, which is younger than the previous age in some cases due to the region not experiencing predicted stress and aging. The control unit is capable of determining a voltage adjustment for the operating voltage reference based on an age indicated by the age counter.

Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.

Abstract: A firing pin lock for firearms is provided. The firing pin lock is a single piece of resilient metal that includes a pocket for receiving the head of the firing pin to prevent inadvertent discharge of the firearm. The firing pin lock can be mounted laterally in the bolt carrier group and is deflected outwardly by the action of the hammer.

Abstract: A method for personalizing media content for a user is provided. The method includes, at an electronic device, streaming a first media item from a first set of media items, the first set of media items compiled using a first recommendation hypothesis. The method further includes, while streaming the first media item, in response to a first user request, selecting, without user intervention, a second set of media items, distinct from the first set of media items, including determining a presentation order of a plurality of sets of media items using a heuristic applied to the plurality of sets of media items. The second set of media items is compiled using a second recommendation hypothesis, wherein the second recommendation hypothesis is distinct from the first recommendation hypothesis. The method includes streaming a second media item from the second set of media items.

Abstract: Methods and systems are provided that determine data characterizing spatial variation of vibrational dysfunction (such as HFTO) along the BHA of a drilling system. In embodiments, such data can be determined from a minimal set of measurements of any or all of four variables that include: vibration amplitude; vibration wavelength; vibration frequency; and the axial position of the first vibrational node. In embodiments, such data can be determined from measurements of vibration amplitude and vibration frequency of a BHA at two fixed positions along the BHA (e.g., with two sensors offset axially along the BHA). In other embodiments, such data can be generated from the estimated position of the first vibrational node and measurements of vibration amplitude and vibration frequency by a single sensor disposed at a fixed axial position along the BHA.

Abstract: A method includes retrieving a plurality of transcripts from a database. Each transcript in the plurality of transcripts corresponds to audio from a media content item of a plurality of media content items that are provided by a media providing service. The method also includes applying each transcript of the plurality of transcripts to a trained computational model, and receiving a user request for information regarding a topic. The method further includes, in response to the user request, identifying a transcript from the database that is relevant to the topic, and a position within the transcript that is relevant to the topic. The method also includes providing, by the media providing service, at least a portion of a media content item corresponding to the identified transcript, beginning at a starting position that is based on the position within the identified transcript that is relevant to the topic.

Abstract: Stable pharmaceutical formulations for therapeutic anti-IL-23p19 antibodies and methods of using such stable pharmaceutical formulations.

Abstract: A housing includes a cavity portion and a cover portion configured for rotary motion. The cover portion can include a receiver port configured to engage with a fitting configured for coupling to an end of a first tube. At a first alignment position of the cavity portion relative to the cover portion, the receiver port is aligned with a first retention cleat. At a second alignment position of the cavity portion relative to the cover portion, the receiver port is aligned with a fluid coupler. At a third alignment position of the cavity portion relative to the cover portion, the fitting is aligned with a second cap.

Abstract: Anti-CD3 antibodies for use in the diagnosis or treatment of hyperproliferative or autoimmune disorders methods of using the same for detecting and/or treating a hyperproliferative or autoimmune disorders.

Abstract: A personal vehicle system including a control system and at least one wheel motor coupled to the personal vehicle system and subject to control by the control system. A control system for a personal vehicle system including steps for calibrating the control system, where the control system includes a sensor system having load sensors incorporated into the personal vehicle system and also having lean forward and lean backward outputs, a user interface that prompts a user to lean forward and backward and allows a user to input a sensitivity value, and an electronic hardware component for calculating a normalization value where the wheel motor current is controlled as a function of the normalization value.

Abstract: A housing includes a cavity portion and a cover portion configured for rotary motion. The cover portion can include a receiver port configured to engage with a fitting configured for coupling to an end of a first tube. At a first alignment position of the cavity portion relative to tire cover portion, the receiver port is aligned with a first retention cleat. At a second alignment position of the cavity portion relative to the cover portion, the receiver port is aligned with a fluid coupler. At a third alignment position of the cavity portion relative to the cover portion, the fitting is aligned with a second cap.