Patents by Inventor Aaron R. Ellison

Aaron R. Ellison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030138787
    Abstract: An invention is described which provides a diagnostic approach for diseases, such as HNPCC, that are associated with defects in MMR and provides a method for determining whether any specific genetic sequence of a gene associated with MMR that differs from a consensus sequence is a mutation (i.e., encodes a non-functional protein), a silent polymorphism (i.e., encodes a protein with normal protein function) or an efficiency polymorphism (i.e., encodes a protein with reduced efficiency in MMR). The invention allows the generation of databases of the functional significance of specific amino acid replacements on MMR protein function in vivo, which in turn will allow accurate and unambiguous interpretation of genetic tests of MMR.
    Type: Application
    Filed: March 29, 2002
    Publication date: July 24, 2003
    Inventors: Grant A. Bitter, Aaron R. Ellison