Abstract: A method for detection of an evoked response signal in noise including: generating a plurality of stimuli; receiving a noisy signal related to an evoked response to the plurality of stimuli; divide the noisy signal into a plurality of responses to the plurality of stimuli; estimate a statistic matrix for the plurality of responses; shrink the statistic matrix; calculate weights based on an inverse of the shrunk statistic matrix; apply weights to the plurality of responses to construct a final response; and output the final response. An apparatus having an input device configured to receive data related to a plurality of stimuli; and a processor configured to: receive a noisy signal and divide the noisy signal into a plurality of responses; estimate a statistic matrix; shrink the statistic matrix; calculate weights based on an inverse of the shrunk statistic matrix; and apply weights to the plurality of responses to construct a final response.

Abstract: A method for detection of an evoked response signal in noise including: generating a plurality of stimuli; receiving a noisy signal related to an evoked response to the plurality of stimuli; divide the noisy signal into a plurality of responses to the plurality of stimuli; estimate a statistic matrix for the plurality of responses; shrink the statistic matrix; calculate weights based on an inverse of the shrunk statistic matrix; apply weights to the plurality of responses to construct a final response; and output the final response. An apparatus having an input device configured to receive data related to a plurality of stimuli; and a processor configured to: receive a noisy signal and divide the noisy signal into a plurality of responses; estimate a statistic matrix; shrink the statistic matrix; calculate weights based on an inverse of the shrunk statistic matrix; and apply weights to the plurality of responses to construct a final response.

Abstract: A system and method for filtering a signal comprising: receiving a signal of interest; receiving a signal indicating that a stimulus has been applied; receiving the synchronized stimulus signal and signal of interest; recursively selecting a portion of the signal of interest associated with a stimulus being applied and assign the selected portion of the signal of interest to one of the plurality of buffers; combining all responses in each of said plurality of buffers; transforming the combination of all responses in each buffer to a transform space; comparing the transform components of the buffers to determine a scaling factor; applying the scaling factor to the spectral components of the buffers; performing an inverse transform on the result of combining the buffers to return to the time domain to produce a filtered signal, and outputting the filtered signal received from the processor.

Abstract: A system and method for filtering a signal comprising: receiving a signal of interest; receiving a signal indicating that a stimulus has been applied; receiving the synchronized stimulus signal and signal of interest; recursively selecting a portion of the signal of interest associated with a stimulus being applied and assign the selected portion of the signal of interest to one of the plurality of buffers; combining all responses in each of said plurality of buffers; transforming the combination of all responses in each buffer to a transform space; comparing the transform components of the buffers to determine a scaling factor; applying the scaling factor to the spectral components of the buffers; performing an inverse transform on the result of combining the buffers to return to the time domain to produce a filtered signal, and outputting the filtered signal received from the processor.