Abstract: Provided herein are compositions of chimeric shuttle-binder-effector fusion proteins with components related to modulating endogenous cytotoxic effector mechanisms, which are useful for therapeutic effects on predetermined target molecules. These shuttle-binder-effector proteins also have specific epitope binding affinities for these target molecules. Compositions for modified cells expressing these chimeric shuttle-binder-effector fusion proteins are also provided. Methods for the modification of cells to express these chimeric shuttle-binder-effector fusion proteins and for delivering the chimeric shuttle-binder-effector fusion proteins into target cells using the lytic granule cellular mechanisms in these modified cells are also provided.

Abstract: A system for a cookware lid holder including a mounting assembly, an arm adjusting assembly and a lid clamping assembly is disclosed. The mounting assembly allows securing of the system to any surface, primarily with the use of a clamp. Once the system is secured it is possible to adjust the positions and angles of the arm adjusting assembly as is most comfortable and suitable for a user. The arm adjusting assembly allows for customization in order to position lids of cooking pots to be held out of the way when storing or when cooking even. The lid clamping assembly permits for lids of predetermined dimensions to be secured and moved about with the arm adjusting assembly. The arm adjusting assembly includes a first and second holding arm that expand outwardly if need be. The lids can be moved freely while being held due to an arm pivot.

Abstract: An assembly for locking an oven door mounted on a body of a range and movable between open and closed positions, is provided that comprises a mount bracket adapted to be secured to the range body, with the mount bracket having a base and a cradle protruding below the base and disposed above an oven top wall. A latch member is coupled to the mount bracket for movement relative to the bracket. A locking device is disposed at least partially within the cradle and includes a thermally responsive element and a locking member coupled to the thermally responsive element. A heat transfer member has a first end adapted to be secured to the oven top wall and a second end secured to the cradle, wherein the locking member prevents the latch member from moving from a position where the door is latched and forced against the range body by the latch member toward a position wherein the door can be opened, when the thermally responsive member is actuated.