Patents by Inventor Aaron Whiteley

Aaron Whiteley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR THE GENERATION OF PROGRAMABLE POST-TRANSLATIONAL PROTEIN MODIFICATION AND HYDROLYSIS
    Publication number: 20230287362
    Abstract: The invention describes the discovery and novel application of a bacterial ubiquitin transferase (Cap2). Specifically, the invention describes the novel activity of the enzyme Cap2 which is capable of creating a specific fusion between two proteins implementing a standalone catalytic mechanism to create the fusion.
    Type: Application
    Filed: March 14, 2023
    Publication date: September 14, 2023
    Inventors: Aaron Whiteley, Hannah Ledvina, Kevin Corbett, Qiaozhen Ye, Yajie Gu
  • CGAS/DNCV-LIKE NUCLEOTIDYLTRANSFERASES AND USES THEREOF
    Publication number: 20220127586
    Abstract: The present invention is based, in part, on the discovery and characterization of the CD-NTase family of proteins, as well as compositions comprising CD-NTases, methods of producing nucleotide-based second messengers using such polypeptides, and methods of screening for modulators of the structure, expression, and/or activity of such polypeptides.
    Type: Application
    Filed: September 4, 2019
    Publication date: April 28, 2022
    Inventors: Aaron Whiteley, Philip J. Kranzusch, John Mekalanos, James Eaglesham