Patents by Inventor Aashiq Hussain

Aashiq Hussain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 10-substituted colchicinoids as potent anticancer agents
    Patent number: 9868695
    Abstract: The present invention relates to the compounds of formula I wherein R is as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10-substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: January 16, 2018
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ram A. Vishwakarma, Sandip B. Bharate, Ajay Kumar, Baljinder Singh, Ashok Kumar, Shashi Bhushan, Abid Hamid, Prashant Joshi, Santosh K. Guru, Suresh Kumar, Aashiq Hussain, Asif K. Qazi, Sonali S. Bharate, Parduman Sharma, Ajit K. Saxena, Dilip M. Mondhe, Girish Mahajan, Zahoor Wani
  • Chromone alkaloid dysoline for the treatment of cancer and inflammatory disorders
    Patent number: 9776989
    Abstract: The present invention relates to novel chromone alkaloid of formula 1 isolated from the plant Dysoxylum binectariferum. The compound 5,7-dihydroxy-6-(3-hydroxy-1-methylpiperidin-4-yl)-2-methyl-4H-chromen-4-one, is found to be a potential inhibitor of cell growth and proliferation and also inhibits production of pro-inflammatory cytokines. The formulations of this particular compound can be used for treatment of cancer and inflammation.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: October 3, 2017
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Ram Asrey Vishwakarma, Shreyans Kumar Jain, Sandip Bibishan Bharate, Abid Hamid Dar, Anamika Khajuria, Samdarshi Meena, Sunil Kumar Bhola, Asif Khurshid Qazi, Aashiq Hussain, Tabasum Sidi, Shaanker Ramanan Uma, Gudasalamani Ravikanth, Ramesh Vasudeva, Kumara Patel Mohana, Kotiganahalli Narayanagowda Ganeshaiah
  • 10-SUBSTITUTED COLCHICINOIDS AS POTENT ANTICANCER AGENTS
    Publication number: 20170226051
    Abstract: The present invention relates to the compounds of formula I wherein R is as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10-substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease.
    Type: Application
    Filed: October 14, 2015
    Publication date: August 10, 2017
    Inventors: Ram A. Vishwakarma, Sandip B. Bharate, Ajay Kumar, Baljinder Singh, Ashok Kumar, Shashi Bhushan, Abid Hamid, Prashant Joshi, Santosh K. Guru, Suresh Kumar, Aashiq Hussain, Asif K. Qazi, Sonali S. Bharate, Parduman Sharma, Ajit K. Saxena, Dilip M. Mondhe, Girish Mahajan, Zahoor Wani
  • NOVEL CHROMONE ALKALOID DYSOLINE FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISORDERS
    Publication number: 20160046611
    Abstract: The present invention relates to novel chromone alkaloid of formula 1 isolated from the plant Dysoxylum binectariferum. The compound 5,7-dihydroxy-6-(3-hydroxy-1-methylpiperidin-4-yl)-2-methyl-4H-chromen-4-one, is found to be a potential inhibitor of cell growth and proliferation and also inhibits production of pro-inflammatory cytokines. The formulations of this particular compound can be used for treatment of cancer and inflammation.
    Type: Application
    Filed: March 31, 2014
    Publication date: February 18, 2016
    Inventors: Ram Asrey Vishwakarma, Shreyans Kumar Jain, Sandip Bibishan Bharate, Abid Hamid Dar, Anamika Khajuria, Samdarshi Meena, Sunil Kumar Bhola, Asif Khurshid Qazi, Aashiq Hussain, Tabasum Sidi, Shaanker Ramanan Uma, Gudasalamani Ravikanth, Ramesh Vasudeva, Kumara Patel Mohana, Kotiganahalli Narayanagowda Ganeshaiah
  • Boronic acid bearing liphagane compounds as inhibitors of P13K-? and/or ?
    Patent number: 9206201
    Abstract: Compounds with unique liphagane meroterpenoid scaffold having boronic acid functionality in the skeleton are described (formula 1) together with pharmacological potential of these compounds as anticancer agents. A method of preparation and inhibiting the activity of phosphoinositide-3-kinase (PI3K-alpha and beta) has been presented. In particular, the invention describes a method of inhibiting PI3K isoforms, wherein the compounds are novel structures based on liphagane scaffold with unique boronic acid functionality. The methods and uses thereof are described herein this invention.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: December 8, 2015
    Assignee: Counsel of Scientific & Industrial Research
    Inventors: Ram Asrey Vishwakarma, Sanghapal Damodhar Sawant, Parvinder Pal Singh, Abid Hamid Dar, Parduman Raj Sharma, Ajit Kumar Saxena, Amit Nargotra, Anjaneya Aravind Kumar Kolluru, Ramesh Mudududdla, Asif Khurshid Qazi, Aashiq Hussain, Nayan Chanauria
  • BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF P13K- a AND/OR B
    Publication number: 20150051173
    Abstract: Compounds with unique liphagane meroterpenoid scaffold having boronic acid functionality in the skeleton are described (formula 1) together with pharmacological potential of these compounds as anticancer agents. A method of preparation and inhibiting the activity of phosphoinositide-3-kinase (PI3K-alpha and beta) has been presented. In particular, the invention describes a method of inhibiting PI3K isoforms, wherein the compounds are novel structures based on liphagane scaffold with unique boronic acid functionality. The methods and uses thereof are described herein this invention.
    Type: Application
    Filed: March 18, 2013
    Publication date: February 19, 2015
    Inventors: Ram Asrey Vishwakarma, Sanghapal Damodhar Sawant, Parvinder Pal Singh, Abid Hamid Dar, Parduman Raj Sharma, Ajit Kumar Saxena, Amit Nargotra, Anjaneya Aravind Kumar Kolluru, Ramesh Mudududdla, Asif Khurshid Qazi, Aashiq Hussain, Nayan Chanauria