Abstract: Methods and systems for multi-region database configuration in a distributed computing system are disclosed. A database comprising at least three voting replicas of a partition of a table is stored by a cluster of computing nodes. The database corresponds to one or more database regions that are each indicative of a geographic location corresponding to the cluster of computing nodes. Each of the voting replicas participates in voting to commit write operations to the partition. At least three computing nodes of the cluster each store a respective voting replica of the voting replicas, where each of the computing nodes is located within one of a first, second, or third database region of the database regions. Each of the database regions that does not store one of the voting replicas stores a non-voting replica that does not participate in the voting to commit the write operations to the partition.