Abstract: The present invention relates to a compound of the following formula (I) and pharmaceutical compositions containing the compound of formula (I): wherein D, Y, A, B, p, q, W and R have the same meanings as defined in the specification.

Abstract: The invention concerns the use of a piperazine derivative of formula (I) wherein: A and B=C═O, C═S or CR7R8 with R7=H, methyl, cyano, cyanomethyl, CO2CH3 or (C═O)CH3 and R8=H or phenyl; R1 to R6=H, OH, or C1-C5 alkoxy; X represents: either C═O, O(C═O), O(C═S), O(SO2), NH(C═O), NH(C═S), NH(SO2), S(C═O) or S(C═S), then Y=NR9R10, CR9R10R11 in which R9, R10 and R11=H, C1-C5 alkyl, C2-C5 alkenyl, or C2-C5 alkynyl or Y=nitrogenous heterocycle comprising 5 to 10 atoms; or X represents O, S, O(C═O)O, NH(C═O)O, or S(C═O)O, then Y=CR9R10R11 with R9, R10, R11 as above; or one of its pharmaceutically acceptable salts for preparing a medicine inhibiting HIV. The invention is useful for treating HIV infection.

Abstract: A compound selected from those of formula (I): ##STR1## in which A represents ##STR2## X represents N--R.sub.4 or oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, n and m are as defined in the description,useful in improving glucose tolerance in the treatment of non-insulin-dependent diabetes.

Abstract: A compound selected from those of formula (I): ##STR1## in which A represents ##STR2## X represents N-R.sub.4 or oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, n and m are as defined in the description, useful in improving glucose tolerance in the treatment of non-insulin-dependent diabetes.