Patents by Inventor Abdelqader Zamamiri

Abdelqader Zamamiri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF IMPROVING PROTEIN TITER IN CELL CULTURE
    Publication number: 20250059501
    Abstract: Methods of improving recombinant protein titer and cell titer in cell culture using cell culture media having reduced impurities are provided, and well as cell culture media having reduced impurities that can used for the production of a recombinant protein and cells with improved titer. The cell culture media having reduced impurities comprises a HEPES buffer, and the reduced impurities are HEPES related impurities. In certain aspects, methods and media improve protein titer, cell growth, and/or viable cell density.
    Type: Application
    Filed: May 24, 2024
    Publication date: February 20, 2025
    Inventors: Reginald Smith, Sarah Nicoletti, Victor Shashilov, Hongxia Wang, Jikang Wu, Abdelqader Zamamiri
  • Methods of improving protein titer in cell culture
    Patent number: 12031151
    Abstract: Methods of improving recombinant protein titer and cell titer in cell culture using cell culture media having reduced impurities are provided, and well as cell culture media having reduced impurities that can used for the production of a recombinant protein and cells with improved titer. The cell culture media having reduced impurities comprises a HEPES buffer, and the reduced impurities are HEPES related impurities. In certain aspects, methods and media improve protein titer, cell growth, and/or viable cell density.
    Type: Grant
    Filed: January 19, 2022
    Date of Patent: July 9, 2024
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Reginald Smith, Sarah Nicoletti, Victor Shashilov, Hongxia Wang, Jikang Wu, Abdelqader Zamamiri
  • METHODS OF IMPROVING PROTEIN TITER IN CELL CULTURE
    Publication number: 20220228107
    Abstract: Methods of improving recombinant protein titer and cell titer in cell culture using cell culture media having reduced impurities are provided, and well as cell culture media having reduced impurities that can used for the production of a recombinant protein and cells with improved titer. The cell culture media having reduced impurities comprises a HEPES buffer, and the reduced impurities are HEPES related impurities. In certain aspects, methods and media improve protein titer, cell growth, and/or viable cell density.
    Type: Application
    Filed: January 19, 2022
    Publication date: July 21, 2022
    Inventors: Reginald Smith, Sarah Nicoletti, Victor Shashilov, Hongxia Wang, Jikang Wu, Abdelqader Zamamiri
  • High throughput bioreactor
    Patent number: 7901937
    Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: March 8, 2011
    Assignee: Regents of the University of Minnesota
    Inventors: Friedrich Srienc, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar
  • HIGH THROUGHPUT BIOREACTOR
    Publication number: 20090081770
    Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.
    Type: Application
    Filed: November 3, 2008
    Publication date: March 26, 2009
    Applicant: Regents of the University of Minnesota
    Inventors: FRIEDRICH SRIENC, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar
  • High throughput bioreactor
    Publication number: 20040214314
    Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.
    Type: Application
    Filed: November 1, 2002
    Publication date: October 28, 2004
    Inventors: Friedrich Srienc, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar