Patents by Inventor Abdul E. Mutlib

Abdul E. Mutlib has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isatin derivatives as acetylcholinesterase inhibitors and analgesics
    Patent number: 6100276
    Abstract: This application relates to compounds of the formula ##STR1## wherein R, X and Y are defined within, which compounds are useful for the treatment of memory dysfunction characterized by decreased cholinergic function, and for analgesia, pharmaceutical compositions containing the compounds and methods for making and using the compounds.
    Type: Grant
    Filed: February 24, 1997
    Date of Patent: August 8, 2000
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Stephen J. Shimshock, Susan M. Chesson, Abdul E. Mutlib
  • Substituted benzothienylpiperazines and their use
    Patent number: 5801176
    Abstract: This invention relates to compounds of the formula ##STR1## wherein X is halogen, hydroxy, (C.sub.1 -C.sub.6)alkoxy, amino or trifluoromethyl; andY is --CN or --NR.sup.1 R.sup.2 ;wherel is an integer of 0, 1 or 2;m is an integer of 0, 1 or 2;n is an integer of 2, 3 or 4, except when Y is CN, in which case n can also be 1;R.sup.1 is hydrogen, (C.sub.1 -C.sub.6)alkyl or (C.sub.1 -C.sub.6)alkylcarbonyl;R.sup.2 is hydrogen, (C.sub.1 -C.sub.10)alkylcarbonyl, (C.sub.3 -C.sub.12)cycloalkylcarbonyl, hydroxy-(C.sub.1 -C.sub.6)alkylcarbonyl, phenylcarbonyl, thienylcarbonyl or benzothienylcarbonyl;orR.sub.1 and R.sup.2 together with nitrogen atom to which they are attached form the ring ##STR2## where A is C.dbd.O or CH.sub.2 ;andB is C.dbd.O, CHOH, CH.sub.2 or CH.sub.2 CH.sub.2 ; andZ is halogen, hydroxy, (C.sub.1 -C.sub.6)alkoxy, amino or trifluoromethyl p is 0 or 1; and pharmaceutically acceptable acid addition salts thereof, pharmaceutical compositions thereof and their use for the treatment of psychoses.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: September 1, 1998
    Assignee: Hoechst Marion Roussel, Inc.
    Inventors: Nicholas Joseph Hrib, John Gerard Jurcak, Abdul E. Mutlib