Abstract: There is disclosed a formulation suitable for the reduction or prevention of contamination of articles by microorganisms. The formulation includes at least one block copolymer of ethylene oxide and propylene oxide, at least one polyacrylic acid salt, and at least one propoxylated ethylenediamine compound.

Abstract: The present technology relates to a patient interface for use in delivering breathable gas to a patient. The patient interface may comprise a cushion module and a frame. The cushion module may comprise a cushion and a cushion clip. The cushion clip may be configured to hold the cushion module in a substantially fixed position relative to the frame in use. In some forms, the frame and the cushion module are configured to connect together interlocks between the cushion module and the frame is configured to flex to alter a distance between interlocks, and wherein flexing the frame enables the cushion module to be disconnected from the frame.

Abstract: An apparatus is provided. The apparatus comprises interface circuitry, machine-readable instructions and processing circuitry to execute the machine-readable instructions. The machine-readable instruction may be stored on a storage device. The machine-readable instructions is to receive, from an interface apparatus, user data indicative of a hardware microservice requested by a user. Further, it is to receive, from a database, microservice data indicative of a plurality of hardware microservices. Further, it is to determine a hardware microservice based on the plurality of hardware microservices and the requested hardware microservice of the user.

Abstract: Various examples relate to apparatuses, devices, methods and computer programs for wrapping a monolithic application. In one aspect, such an apparatus is to observe a behavior of the monolithic application, and to provide a wrapper for wrapping the monolithic application, the wrapper comprising an interface that exposes one or more capabilities of the monolithic application to a microservice managing platform, with the interface being based on the observed behavior.

Abstract: A method of screening for a drug combination for treating colorectal carcinoma, the screened drug combination and its related application are provided. The drug combination includes at least three selected from Regorafenib, Gemcitabine, Cetuximab and 5-Fluorouracil. With the method of the disclosure, the best and novel drug combination can be selected from the existing clinical drugs, the technical effect of rapidly screening for a drug combination can be achieved, and the screened combination drug has an excellent therapeutic effect.

Abstract: An apparatus is provided. The apparatus comprises interface circuitry, machine-readable instructions and processing circuitry to execute the machine-readable instructions. The machine-readable instruction may be stored on a storage device. The machine-readable instructions is to receive, from an interface apparatus, user data indicative of a hardware microservice requested by a user. Further, it is to receive, from a database, microservice data indicative of a plurality of hardware microservices. Further, it is to determine a hardware microservice based on the plurality of hardware microservices and the requested hardware microservice of the user.

Abstract: The invention relates to a method for predicting, selecting and screening a personalised combinatorial therapy for a patient comprising the steps of measuring a response output for each drug candidate in a sample obtained from the patient; determining a minimum set of test combinatorial therapies according to a composite experimental design, such as an orthogonal array composite design; measuring a response output and determining a relationship between the response output and the corresponding predetermined doses of the candidate drugs; and consequently deriving an optimal drug-dose combination for treating the patient.

Abstract: A battery module includes a first load terminal, a second load terminal, a first charger terminal, a charger enable terminal, and a battery having a first battery terminal coupled to the first load terminal and a second terminal coupled to the second load terminal. A first isolation device is coupled between the first load terminal and the first charger terminal and has an enable terminal coupled to the charger enable terminal. A first protection circuit includes a second isolation device coupled between the second battery terminal and the second load terminal and a first sensing circuit configured to enable the second isolation device responsive to detecting a failure of the first isolation device.

Abstract: A processing module is provided. The processing module includes one or more interfaces configured to communicate with at least one integrated development environment and processing circuitry configured to control the one or more interfaces. The processing circuitry is further configured to obtain information about at least one hardware microservice of a processing unit, adapt the information about the at least one hardware microservice to a universal format for informing the at least one IDE about the at least one hardware microservice and provide the at least one IDE access to the at least one hardware microservice.

Abstract: The disclosure generally provides methods, systems and apparatus for functional safety systems. In one implementation, a shim layer of software codes that maps into register information collects diagnostic error data. The data is then channeled through one or more virtual tunnels into a Host-based STL. The virtual tunnels are unidirectional to only provide Read access and thereby prevent unauthorized Write access. In another embodiment, the information is provided to external subscribers. The external subscribers may gain access to different levels of data according to the subscription level.

Abstract: A processing unit is provided. The processing unit includes one or more interfaces configured to communicate with at least one hardware component and processing circuitry configured to control the one or more interfaces and to determine a superset of a plurality of hardware microservices of the at least one hardware component.

Abstract: Methods, apparatus, systems and articles of manufacture disclosed herein expose a microservice to a software layer. A disclosed method includes composing an API execution recipe, initializing a software service to be called, and checking, by executing an instruction with the at least one processor. The connection is between a software layer and a microservice, is defined by the API execution recipe, and is to expose the microservice to the software layer.

Abstract: The present invention provides a poly(ethylene) glycol based polyurethane polymer composition, particularly useful in the production of contact lenses. Generally the reactant mixture used to form the polymer includes a branched chain extender. There is also provided a method of manufacturing a contact lens formed from such a polymer.

Abstract: There is disclosed a formulation suitable for the reduction or prevention of contamination of articles by microorganisms. The formulation includes at least one block copolymer of ethylene oxide and propylene oxide, at least one polyacrylic acid salt, and at least one propoxylated ethylenediamine compound.

Abstract: A battery module includes a first load terminal, a second load terminal, a first charger terminal, a charger enable terminal, and a battery having a first battery terminal coupled to the first load terminal and a second terminal coupled to the second load terminal. A first isolation device is coupled between the first load terminal and the first charger terminal and has an enable terminal coupled to the charger enable terminal. A first protection circuit includes a second isolation device coupled between the second battery terminal and the second load terminal and a first sensing circuit configured to enable the second isolation device responsive to detecting a failure of the first isolation device.

Abstract: A modified reference transformation removes weighting factor from predictive torque control, and a reduced order PI observer based disturbance rejection control (DOBC) is combined to improve transient response. The resulting scheme shows superior performance as compared to previously proposed methods. The superiority of the disclosed MPTC is demonstrated by lower load estimation error and effective current surge suppression at speed jumps while maintaining comparable inner loop performance. Moreover, removal of weighting factor from the cost function gives an additional benefit of optimal balance between flux and torque regulation as evident from simulation and experimental results.

Abstract: A system and method for monitoring a predetermined condition in a harsh environment, includes wireless sensor nodes each having a physical clock and a soft clock. The sensor configured to detect the predetermined condition. Each wireless sensor node remains in a sleep mode, then independently, when a triggering event is true, the soft clock evolves a value of a dynamical local time variable using time variable values communicated by random other of the wireless sensor nodes that are within a single hop based on the harsh environment, infers from its dynamical local time variable the communication instant at which the dynamical local time variable is closest to the time value of the gateway node, and initializes the physical clock using the value of the dynamical local time variable at that instant to generate and communicate the local node time through the gateway node to the end-user device.

Abstract: The disclosure generally provides methods, systems and apparatus for functional safety systems. In one implementation, a shim layer of software codes that maps into register information collects diagnostic error data. The data is then channeled through one or more virtual tunnels into a Host-based STL. The virtual tunnels are unidirectional to only provide Read access and thereby prevent unauthorized Write access. In another embodiment, the information is provided to external subscribers. The external subscribers may gain access to different levels of data according to the subscription level.

Abstract: Disclosed are pharmaceutical compositions and methods of treating multiple myeloma by providing a pharmaceutically effective amount of each drug in a combination of drugs.

Abstract: The invention provides methods and materials for use in the detection of influenza viruses which utilise a nanoparticle, for example gold nanoparticle, probe comprising a plurality of glycoconjugate ligands, each glyconjugate ligand (GL) having a plurality of sialic-acid containing recognition group (Y) coupled to the nanoparticle via a multivalent core (X), wherein the multivalent core (X) is a trivalent core, whereby there are 3 recognition groups per ligand, wherein the recognition groups on the bioconjugate specifically bind to the hemagglutinin on the target influenza virus. The probes may include further ligands bound to the nanoparticle which do not bind specifically to an influenza virus—for example polyethylene glycol groups. These can modulate density of the glycoconjugate ligand on the surface of the nanoparticle. Binding of probes is detected by a plasmonic signal which is specific to the influenza virus.