Patents by Inventor ABDULLA AL-TAHER

ABDULLA AL-TAHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-SARS-CoV-2 fusion peptides
    Patent number: 11479582
    Abstract: Anti-SARS-CoV-2 fusion peptides are provided. The anti-SARS-CoV-2 fusion peptides include peptide sequences corresponding to the sequence of the SARS-CoV-2 fusion complex heptad repeat domain HR2 and having at least one artificial mutation. The anti-SARS-CoV-2 fusion peptides may be 39-mers, such as peptides #121 (SEQ ID NO: 2) and #125 (SEQ ID NO: 5). These peptides may competitively bind to SARS-CoV-2 and prevent either membrane mediated SARS-CoV-2 fusion, endocytosis-mediated viral entry, or both. The anti-SARS-CoV-2 fusion peptides may be administered to a subject in need thereof to inhibit or prevent SARS-CoV-2 cellular entry.
    Type: Grant
    Filed: August 24, 2021
    Date of Patent: October 25, 2022
    Assignee: KING FAISAL UNIVERSITY
    Inventors: Mahmoud Kandeel Elsayed, Mizuki Yamamoto, Jin Gohda, Jun-Ichiro Inoue, Yasushi Kawaguchi, Hyung-Joo Kwon, Abdulla Al-Taher
  • ANTI-SARS-COV-2 FUSION PEPTIDES
    Publication number: 20220119456
    Abstract: Anti-SARS-CoV-2 fusion peptides are provided. The anti-SARS-CoV-2 fusion peptides include peptide sequences corresponding to the sequence of the SARS-CoV-2 fusion complex heptad repeat domain HR2 and having at least one artificial mutation. The anti-SARS-CoV-2 fusion peptides may be 39-mers, such as peptides #121 (SEQ ID NO: 2) and #125 (SEQ ID NO: 5). These peptides may competitively bind to SARS-CoV-2 and prevent either membrane mediated SARS-CoV-2 fusion, endocytosis-mediated viral entry, or both. The anti-SARS-CoV-2 fusion peptides may be administered to a subject in need thereof to inhibit or prevent SARS-CoV-2 cellular entry.
    Type: Application
    Filed: August 24, 2021
    Publication date: April 21, 2022
    Inventors: MAHMOUD KANDEEL ELSAYED, MIZUKI YAMAMOTO, JIN GOHDA, JUN-ICHIRO INOUE, YASUSHI KAWAGUCHI, HYUNG-JOO KWON, ABDULLA AL-TAHER