Patents by Inventor Abdullah Mahmud

Abdullah Mahmud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticle to target cancer
    Patent number: 11696922
    Abstract: A construct, or a pharmaceutically acceptable salt thereof, comprising: (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized; (b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and (c) a siRNA complexed with the poly(L-lysine) of the polymer moiety, wherein the construct is neutralized.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: July 11, 2023
    Assignees: Georgetown University, The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Jill P. Smith, Stephan Stern, Abdullah Mahmud
  • NANOPARTICLE TO TARGET CANCER
    Publication number: 20220211738
    Abstract: A construct, or a pharmaceutically acceptable salt thereof, comprising: (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized; (b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and (c) a siRNA complexed with the poly(L-lysine) of the polymer moiety, wherein the construct is neutralized.
    Type: Application
    Filed: December 17, 2021
    Publication date: July 7, 2022
    Applicants: Georgetown University, The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Jill P. Smith, Stephan Stern, Abdullah Mahmud
  • Nanoparticle to target cancer
    Patent number: 11246881
    Abstract: A construct, or a pharmaceutically acceptable salt thereof, comprising: (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized; (b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and (c) a siRNA complexed with the poly(L-lysine) of the polymer moiety, wherein the construct is neutralized.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: February 15, 2022
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Georgetown University
    Inventors: Jill P. Smith, Stephan Stern, Abdullah Mahmud
  • NANOPARTICLE TO TARGET CANCER
    Publication number: 20190076457
    Abstract: A construct, or a pharmaceutically acceptable salt thereof, comprising: (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized; (b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and (c) a siRNA complexed with the poly(L-lysine) of the polymer moiety, wherein the construct is neutralized.
    Type: Application
    Filed: March 15, 2017
    Publication date: March 14, 2019
    Applicants: Georgetown University, The United States of America, as represented by the Secretary, Department of Health & Human Servic
    Inventors: Jill P. Smith, Stephan Stern, Abdullah Mahmud
  • Poly(ethylene oxide)-block-poly(ester) block copolymers
    Patent number: 9139553
    Abstract: The present invention relates to micelle-forming poly(ethylene oxide)-block-poly(ester) block copolymers having reactive groups on the polyester block therein. The biodegradability of these copolymers and their biocompatibilities with a large number of bioactive agents make them suitable as carriers for various bioactive agents. The bioactive agents, such as DNA, RNA, oligonucleotide, protein, peptide, drug and the like, can be coupled to the reactive groups on the polyester block of the copolymer.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: September 22, 2015
    Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Afsaneh Lavasanifar, Abdullah Mahmud
  • NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS
    Publication number: 20130116428
    Abstract: The present invention relates to micelle-forming poly(ethylene oxide)-block-poly(ester) block copolymers having reactive groups on the polyester block therein. The biodegradability of these copolymers and their biocompatibilities with a large number of bioactive agents make them suitable as carriers for various bioactive agents. The bioactive agents, such as DNA, RNA, oligonucleotide, protein, peptide, drug and the like, can be coupled to the reactive groups on the polyester block of the copolymer.
    Type: Application
    Filed: September 26, 2012
    Publication date: May 9, 2013
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: AFSANEH LAVASANIFAR, ABDULLAH MAHMUD
  • Poly(ethylene oxide)-block-poly(ester) block copolymers
    Patent number: 8309515
    Abstract: The present invention relates to micelle-forming poly(ethylene oxide)-block-poly(ester) block copolymers having reactive groups on the polyester block therein. The biodegradability of these copolymers and their biocompatibilities with a large number of bioactive agents make them suitable as carriers for various bioactive agents. The bioactive agents, such as DNA, RNA, oligonucleotide, protein, peptide, drug and the like, can be coupled to the reactive groups on the polyester block of the copolymer.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: November 13, 2012
    Assignee: The Governors of the University of Alberta
    Inventors: Afsaneh Lavasanifar, Abdullah Mahmud
  • NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS
    Publication number: 20100069295
    Abstract: The present invention relates to micelle-forming poly(ethylene oxide)-block-poly(ester) block copolymers having reactive groups on the polyester block therein. The biodegradability of these copolymers and their biocompatibilities with a large number of bioactive agents make them suitable as carriers for various bioactive agents. The bioactive agents, such as DNA, RNA, oligonucleotide, protein, peptide, drug and the like, can be coupled to the reactive groups on the polyester block of the copolymer.
    Type: Application
    Filed: March 21, 2007
    Publication date: March 18, 2010
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Afsaneh Lavasanifar, Abdullah Mahmud