Patents by Inventor Abeer Al-Ghananeem

Abeer Al-Ghananeem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CO-SOLVENT COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF DANTROLENE THERAPEUTIC AGENTS
    Publication number: 20110160261
    Abstract: The present invention provides for methods of using tert-butyl alcohol (TBA) co-solvent systems in the formulation and production of a pharmaceutical agent with low solubility. The present invention also provides for pharmaceutical compositions made using the novel co-solvent system. In one embodiment, the invention provides for a method of making dantrolene sodium (DS) formulation for intravenous use (DS-IV). This instantaneous reconstitution of the DS-IV product constitutes a significant improvement in the pharmacotherapy of patients undergoing malignant hyperthermia during surgery.
    Type: Application
    Filed: September 5, 2008
    Publication date: June 30, 2011
    Applicant: US WorldMeds, LLC
    Inventors: Ahmad Malkawi, Abeer Al-Ghananeem, Patrick DeLuca, George Digenis
  • CO-SOLVENT COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF DANTROLENE THERAPUTIC AGENTS
    Publication number: 20110015243
    Abstract: The present invention provides for methods of using tert-butyl alcohol (TBA) co-solvent systems in the formulation and production of a pharmaceutical agent with low solubility. The present invention also provides for pharmaceutical compositions made using the novel co-solvent system. In one embodiment, the invention provides for a method of making dantrolene sodium (DS) formulation for intravenous use (DS-IV). This instantaneous reconstitution of the DS-IV product constitutes a significant improvement in the pharmacotherapy of patients undergoing malignant hyperthermia during surgery.
    Type: Application
    Filed: September 5, 2008
    Publication date: January 20, 2011
    Applicant: US WorldMeds, LLC
    Inventors: Ahmad Malkawi, Abeer Al-Ghananeem, Patrick DeLuca, George Digenis
  • LOFEXIDINE ENANTIOMERS FOR USE AS A TREATMENT FOR CNS DISEASE AND PATHOLOGIES AND ITS CHIRAL SYNTHESIS
    Publication number: 20110015246
    Abstract: The invention relates to methods for treatment of CNS disease and pathologies using non-racemic mixtures of lofexidine enantiomers. The invention also relates to processes for the manufacture of chirally pure enantiomers of lofexidine.
    Type: Application
    Filed: March 14, 2006
    Publication date: January 20, 2011
    Applicant: Agean LLC
    Inventors: George Digenis, Peter Crooks, Abeer Al-Ghananeem
  • SUBLINGUAL SPRAY FOR THE TREATMENT OF PAIN
    Publication number: 20090117054
    Abstract: This invention relates to a spray for sublingual administration, used in the treatment and management of pain, especially acute pain. Also provided are methods of treatment and management of pain, a metered dosage system for administration of the spray, and combination therapies.
    Type: Application
    Filed: March 29, 2006
    Publication date: May 7, 2009
    Applicant: University of Kentucky Research Foundation
    Inventors: Peter Crooks, Abeer Al-Ghananeem, Ahmad Malkawi
  • Lofexidine enantiomers for use as a treatment for CNS disease and pathologies and its chiral synthesis
    Publication number: 20080319041
    Abstract: The invention relates to methods for treatment of CNS disease and pathologies using non-racemic mixtures of lofexidine enantiomers. The invention also relates to processes for the manufacture of chirally pure enantiomers of lofexidine.
    Type: Application
    Filed: March 14, 2006
    Publication date: December 25, 2008
    Inventors: George Digenis, Peter A. Crooks, Abeer Al-Ghananeem
  • Scopolamine sublingual spray for the treatment of motion sickness
    Publication number: 20060193784
    Abstract: This invention relates to a scopolamine spray for sublingual administration, used in the treatment and prevention of motion sickness, as well as the treatment and prevention of similar symptoms, such as nausea and vomiting, caused by conditions other than motion sickness. Also provided are methods of treatment, prevention and inhibition of these conditions and symptoms, as well as a metered dosage system for administration of the spray.
    Type: Application
    Filed: February 24, 2006
    Publication date: August 31, 2006
    Inventors: Peter Crooks, Abeer Al-Ghananeem, Ahmad Malkawi