Patents by Inventor Abhay Gaitonde

Abhay Gaitonde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing bosentan
    Patent number: 8785461
    Abstract: The present invention relates to a novel intermediate useful in the preparation of bosentan and to processes for the preparation of said intermediate and bosentan. The invention further relates to compositions comprising bosentan prepared according to the processes of the invention and their use in the treatment of endothelin-receptor mediated disorders.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: July 22, 2014
    Assignee: Generics [UK] Limited
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Mekde, Vikas Padalkar, Hemant Mande
  • Process for the introduction of hydroxyethoxy side chain in bosentan
    Patent number: 8664390
    Abstract: The present invention relates to an improved process for the preparation of bosentan. In particular it relates to a process for preparing bosentan substantially free from the dimer impurity of formula (II) and the 6-hydroxy impurity of formula (III). The invention also relates to a pharmaceutical composition comprising bosentan and its use in the treatment of endothelin-receptor mediated disorders.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: March 4, 2014
    Assignee: Generics (UK) Limited
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Sonawane, Dattatrey Kokane, Sandeep Mekde, Dattatraya Shinde, Prakash Bansode
  • Crystalline forms of bosentan
    Patent number: 8530488
    Abstract: The present invention relates to novel crystalline forms of bosentan and processes for their preparation. Further, the invention relates to pharmaceutical compositions comprising said crystalline forms and use of said compositions in the treatment of patients suffering from endothelin receptor mediated disorders, for example, cardiovascular disorders such as hypertension, pulmonary hypertension, ischemia, vasospasm and angina pectoris.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: September 10, 2013
    Assignee: Generics [UK] Limited
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Mekde, Prakash Bansode, Dattatraya Shinde, Sunanda Phadtare
  • Polymorphic forms
    Patent number: 8288401
    Abstract: Novel polymorphic forms of bosentan and processes for their preparation are disclosed. Further, pharmaceutical compositions comprising said polymorphic forms and the use of said compositions in the treatment of patients suffering from endothelin receptor mediated disorders, for example, cardiovascular disorders such as hypertension, pulmonary hypertension, ischemia, vasospasm and angina pectoris are disclosed.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: October 16, 2012
    Assignee: Generics [UK] Limited
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Mekde, Dattaatraya Shinde, Prakash Bansode
  • NOVEL PROCESS
    Publication number: 20120220799
    Abstract: The present invention relates to a novel process for the preparation of ?-amino acids, such as (±)-3-(aminomethyl)-5-methyl-hexanoic acid 1, which is a key intermediate in the preparation of the potent anticonvulsant pregabalin, (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid 2.
    Type: Application
    Filed: May 10, 2012
    Publication date: August 30, 2012
    Applicant: Generics [UK] Limited
    Inventors: Abhay Gaitonde, Chitra Vaidya, P. Khairnar
  • Preparation of 3-Pyrrole Substituted 2-Indolinone Derivatives
    Publication number: 20110275689
    Abstract: The present invention relates to novel intermediates and further to the use of said intermediates in processes for the preparation of indolinone derivatives, in particular 3-pyrrole substituted 2-indolinones having amide moieties on the pyrrole ring. Such compounds are useful in die treatment of abnormal cell growth, such as cancer, in mammals.
    Type: Application
    Filed: July 1, 2009
    Publication date: November 10, 2011
    Applicant: GENERICS [UK] LIMITED
    Inventors: Abhay Gaitonde, Bharati Choudhari, Prakash Bansode, Sunanda Phadtare
  • PROCESS FOR THE PREPARATION OF CRYSTALLINE FORMS OF SUNITINIB MALATE
    Publication number: 20110257237
    Abstract: The present invention, relates to novel processes for the preparation of sunitinib malate formula (I), pharmaceutical compositions comprising said polymorph and the use of the said pharmaceutical compositions in the treatment of various forms of cancer.
    Type: Application
    Filed: July 9, 2009
    Publication date: October 20, 2011
    Applicant: GENERICS [UK] LIMITED
    Inventors: Abhay Gaitonde, Vinayak Gore, Bharati Choudhari, Mahesh Hublikar, Prakash Bansode, Sunanda Phadtare
  • NOVEL SALT OF TEGASEROD
    Publication number: 20110251254
    Abstract: The present invention relates to a novel salt of tegaserod, namely tegaserod suberate, and to processes for the preparation thereof. The invention also relates to crystalline forms of the novel salt and to pharmaceutical compositions comprising the novel salt. Further, the invention relates to uses of said compositions in treating patients suffering from gastrointestinal disorders.
    Type: Application
    Filed: November 27, 2008
    Publication date: October 13, 2011
    Applicants: Mylan India Private Limited, Generics [UK] Limited
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Rahul Bhalerao, Sinderpal Tank
  • NOVEL POLYMORPHS AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20110112164
    Abstract: The present invention relates to novel polymorph forms III and IV of sunitinib malate, pharmaceutical compositions comprising the novel polymorphs and the use of the pharmaceutical compositions. The present invention further relates to processes for the preparation of polymorph form I, III and IV of sunitinib malate.
    Type: Application
    Filed: February 20, 2009
    Publication date: May 12, 2011
    Applicants: Generics (UK) Limited, Mylan India Private Limited
    Inventors: Abhay Gaitonde, Bharati Choudhari, Prakash Bansode, Sunanda Phadtare
  • PROCESS FOR PREPARING BOSENTAN
    Publication number: 20110039871
    Abstract: The present invention relates to a novel intermediate useful in the preparation of bosentan and to processes for the preparation of said intermediate and bosentan. The invention further relates to compositions comprising bosentan prepared according to the processes of the invention and their use in the treatment of endothelin-receptor mediated disorders.
    Type: Application
    Filed: February 6, 2009
    Publication date: February 17, 2011
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Mekde, Vikas Padalkar, Hemant Mande
  • NOVEL PROCESS FOR THE PREPARATION OF VORINOSTAT
    Publication number: 20110039937
    Abstract: The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient, vorinostat. In particular it relates to an efficient process for the preparation of vorinostat of high purity without the requirement to isolate any synthetic intermediate compounds.
    Type: Application
    Filed: February 6, 2009
    Publication date: February 17, 2011
    Inventors: Abhay Gaitonde, Bharati Choudhari
  • Process for the preparation of anastrozole
    Patent number: 7884213
    Abstract: A process for the preparation of anastrozole.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: February 8, 2011
    Assignee: Generics [UK] Limited
    Inventors: Abhay Gaitonde, Chitra Vaidya, Sanjay R. Pawar
  • NOVEL PROCESS FOR THE PREPARATION OF SCOPINE ESTERS
    Publication number: 20110028508
    Abstract: The present invention relates to novel processes for the preparation of scopine esters and their quaternary salts. In particular, the present invention relates to a process for the preparation of tiotropium bromide, pharmaceutical compositions comprising tiotropium bromide and the use of such compositions in the treatment of respiratory disorders.
    Type: Application
    Filed: January 9, 2009
    Publication date: February 3, 2011
    Applicants: Gemerocs [UK] Limited, Mylan India Private Limited
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Dattatraya Shinde, Sinderpal Tank
  • Process for the preparation of 2-amino-4,5,6,7-tetrahydro-6-aminobenzothiazoles from cyclohexanes and cyclohexanones as intermediates
    Patent number: 7868029
    Abstract: The present invention relates to processes for the preparation of 2-amino-4,5,6,7-tetrahydro-6-aminobenzothiazoles (5a) from cyclohexanes (2a) and cyclohexanones (3a) as intermediate.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: January 11, 2011
    Assignee: Generics [UK] Limited
    Inventors: Ashwini Kumar Gupta, Balu Aghav, Anil Kumar Tripathi, Abhay Gaitonde
  • NOVEL CRYSTALLINE FORMS OF BOSENTAN
    Publication number: 20100331352
    Abstract: The present invention relates to novel crystalline forms of bosentan and processes for their preparation. Further, the invention relates to pharmaceutical compositions comprising said crystalline forms and use of said compositions in the treatment of patients suffering from endothelin receptor mediated disorders, for example, cardiovascular disorders such as hypertension, pulmonary hypertension, ischemia, vasospasm and angina pectoris.
    Type: Application
    Filed: October 24, 2008
    Publication date: December 30, 2010
    Inventor: Abhay Gaitonde
  • PROCESS TO PREGABALIN
    Publication number: 20100324139
    Abstract: The present invention relates to a novel method for the preparation of racemic pregabalin (1) or a single enantiomer thereof, (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid (2).
    Type: Application
    Filed: December 19, 2008
    Publication date: December 23, 2010
    Applicants: Generics [UK] Limited, Mylan India Private Limted
    Inventors: Abhay Gaitonde, Debashish Datta, Bindu Manojkumar, Sunanda Phadtare
  • NOVEL POLYMORPHIC FORMS
    Publication number: 20100261742
    Abstract: Novel polymorphic forms of bosentan and processes for their preparation are disclosed. Further, pharmaceutical compositions comprising said polymorphic forms and the use of said compositions in the treatment of patients suffering from endothelin receptor mediated disorders, for example, cardiovascular disorders such as hypertension, pulmonary hypertension, ischemia, vasospasm and angina pectoris are disclosed.
    Type: Application
    Filed: May 8, 2008
    Publication date: October 14, 2010
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Mekde, Dattatraya Shinde, Prakash Bansode
  • PROCESS FOR THE INTRODUCTION OF HYDROXYETHOXY SIDE CHAIN IN BOSENTAN
    Publication number: 20100249162
    Abstract: The present invention relates to an improved process for the preparation of bosentan. In particular it relates to a process for preparing bosentan substantially free from the dimer impurity of formula (II) and the 6-hydroxy impurity of formula (III). The invention also relates to a pharmaceutical composition comprising bosentan and its use in the treatment of endothelin-receptor mediated disorders.
    Type: Application
    Filed: June 27, 2008
    Publication date: September 30, 2010
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Sonawane, Dattatrey Kokane, Sandeep Mekde, Dattatraya Shinde, Prakash Bansode
  • PROCESS FOR THE PURIFICATION NE OF OLANZAPINE
    Publication number: 20100234590
    Abstract: The present invention relates to a novel process for the preparation of pharmaceutically pure olanzapine. The invention is also related to impurities obtained during the preparation of pharmaceutically pure olanzapine and methods for the detection of the impurities.
    Type: Application
    Filed: May 14, 2008
    Publication date: September 16, 2010
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Rahul Bhalerao, Dattatraya Shinde
  • NOVEL PROCESS
    Publication number: 20100234468
    Abstract: The present invention relates to a process for the preparation of polymorphic forms of the R- and S-enantiomers of modafinil, R-(?)-2-benzhydrylsulfinylacetamide and S-(+)-2-benzhydrylsulfinylacetamide respectively.
    Type: Application
    Filed: May 30, 2008
    Publication date: September 16, 2010
    Inventors: Abhay Gaitonde, Bindu Manojkumar, Sandeep Mekde, Dattatrey Kokane