Patents by Inventor Abhay Kotecha

Abhay Kotecha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210407762
    Abstract: The disclosure relates to a method of imaging a specimen using a transmission charged particle microscope, said method comprising providing a specimen, and providing a charged particle beam and directing said charged particle beam onto said specimen for generating a flux of charged particles transmitted through the specimen. The method comprises the step of generating and recording a first energy filtered flux of charged particles transmitted through the specimen, wherein said first energy filtered flux of charged particles substantially consists of non-scattered and elastically scattered charged particles. The method as disclosed herein comprises the further step of generating and recording a second energy filtered flux of charged particles transmitted through the specimen, wherein said second energy filtered flux of charged particles substantially consists of inelastically scattered charged particles.
    Type: Application
    Filed: June 22, 2021
    Publication date: December 30, 2021
    Applicant: FEI Company
    Inventors: Peter TIEMEIJER, Evgeniia PECHNIKOVA, Rudolf GEURINK, Abhay KOTECHA, Jamie MCCORMACK
  • Patent number: 11053286
    Abstract: The present invention relates to the stabilisation of foot-and-mouth disease virus (FMDV) capsids, by specific substitution of amino acids in a specific region of FMDV VP2. The invention provides stabilised FMDV capsids and vaccines against FMD.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: July 6, 2021
    Assignee: The Pirbright Institute
    Inventors: Abhay Kotecha, David Stuart, Elizabeth Fry, Robert Esnouf
  • Patent number: 10935506
    Abstract: Molecular structure may be determined based on structure factors solved from the diffraction pattern and the electron microscopy image of the sample. In particular, the amplitudes of the structure factors may be determined based on intensities of diffraction peaks in the multiple diffraction patterns. The phases of the structure factors may be determined based on electron microscopy images and the intensities of the diffraction peaks.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: March 2, 2021
    Assignee: FEI Company
    Inventors: Bart Buijsse, Abhay Kotecha
  • Publication number: 20200400594
    Abstract: Molecular structure may be determined based on structure factors solved from the diffraction pattern and the electron microscopy image of the sample. In particular, the amplitudes of the structure factors may be determined based on intensities of diffraction peaks in the multiple diffraction patterns. The phases of the structure factors may be determined based on electron microscopy images and the intensities of the diffraction peaks.
    Type: Application
    Filed: June 24, 2019
    Publication date: December 24, 2020
    Applicant: FEI Company
    Inventors: Bart Buijsse, Abhay Kotecha
  • Patent number: 10294277
    Abstract: The present invention relates to the stabilization of foot-and-mouth disease virus (FMDV) capsids, by specific substitution of amino acids in a specific region of FMDV VP2. The invention provides stabilized FMDV capsids and vaccines against FMD.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: May 21, 2019
    Assignee: The Pirbright Institute
    Inventors: Abhay Kotecha, David Stuart, Elizabeth Fry, Robert Esnouf
  • Publication number: 20190135874
    Abstract: The present invention relates to the stabilisation of foot-and-mouth disease virus (FMDV) capsids, by specific substitution of amino acids in a specific region of FMDV VP2. The invention provides stabilised FMDV capsids and vaccines against FMD.
    Type: Application
    Filed: January 17, 2019
    Publication date: May 9, 2019
    Applicant: Pirbright Institute
    Inventors: Abhay Kotecha, David Stuart, Elizabeth Fry, Robert Esnouf
  • Publication number: 20160052973
    Abstract: The present invention relates to the stabilisation of foot-and-mouth disease virus (FMDV) capsids, by specific substitution of amino acids in a specific region of FMDV VP2. The invention provides stabilised FMDV capsids and vaccines against FMD.
    Type: Application
    Filed: March 25, 2014
    Publication date: February 25, 2016
    Applicant: Pirbright Institute
    Inventors: Abhay Kotecha, David Stuart, Elizabeth Fry, Robert Esnouf