Patents by Inventor Abhigyan Som
Abhigyan Som has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20210137122Abstract: A disinfectant includes a source of chlorine, a buffer system, a pH adjuster, and a polar carrier. The disinfectant has a pH of 9.9-11 and activity against Clostridium difficile spores and Mycobacterium within a 3 minute kill time. In one embodiment, the disinfectant includes sodium hypochlorite as a source of chlorine, a carbonate or phosphate buffer system, a hydroxide pH adjuster, and a polar carrier, wherein the disinfectant has a pH of 10.0-10.5 and kills at least 90% of Clostridium difficile spores and Mycobacterium within a 3 minute kill time.Type: ApplicationFiled: January 11, 2021Publication date: May 13, 2021Inventors: Abhigyan Som, Olga Borokhov, Timothy J. Taylor, Harish Jani, Anabell Jackson, Robert Carrier
-
Patent number: 10897905Abstract: A disinfectant includes a source of chlorine, a buffer system, a pH adjuster, and a polar carrier. The disinfectant has a pH of 9.9-11 and activity against Clostridium difficile spores and Mycobacterium within a 3 minute kill time. In one embodiment, the disinfectant includes sodium hypochlorite as a source of chlorine, a carbonate or phosphate buffer system, a hydroxide pH adjuster, and a polar carrier, wherein the disinfectant has a pH of 10.0-10.5 and kills at least 90% of Clostridium difficile spores and Mycobacterium within a 3 minute kill time.Type: GrantFiled: January 25, 2017Date of Patent: January 26, 2021Assignee: METREX RESEARCH, LLCInventors: Abhigyan Som, Olga Borokhov, Timothy J. Taylor, Harish Jani, Anabell Jackson, Robert Carrier
-
Patent number: 10493159Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: GrantFiled: October 23, 2018Date of Patent: December 3, 2019Assignee: University of MassachusettsInventors: Gregory N. Tew, Gregory J. Gabriel, Abhigyan Som, Arife Ozgul Tezgel
-
Patent number: 10321975Abstract: A method for continuously evaluating the effectiveness of debridement of a root canal of a tooth, the tooth having an open access cavity and an apex end, includes delivering a fluid to the open access cavity of the tooth, evacuating the fluid near the apex end of the tooth such that the fluid flushes most of the root canal before being evacuated, and continuously evaluating the evacuated fluid for at least one of a presence of debris, a concentration level of the debris, or a type of the debris. An apparatus for use in debriding a root canal of a tooth includes a microcannula or a macrocannula configured to evacuate a fluid in the root canal, and a sensing mechanism fluidically coupled to the microcannula or the macrocannula, the sensing mechanism configured to continuously sense debris in the evacuated fluid in real time.Type: GrantFiled: May 25, 2017Date of Patent: June 18, 2019Assignee: Ormco CorporationInventors: Steven Joseph Burns, Emanuele Maretto, Abhigyan Som, Carlos Alberto Munoz, Matteo Bosisio, Gopikrishnan Soundararajan, Tuyen Nguyen, M. Reza Mehrabi
-
Publication number: 20190091337Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: ApplicationFiled: October 23, 2018Publication date: March 28, 2019Inventors: Gregory N. Tew, Gregory J. Gabriel, Abhigyan Som, Arife Ozgul Tezgel
-
Patent number: 10235861Abstract: A mobile device that includes an input device, an output device, and an electronic processor connected to the input device and the output device. The electronic processor is configured to receive, from the input device, information about a disinfectant and set a threshold time, a threshold activity level, or both the threshold time and the threshold activity level based on the information about the disinfectant. The electronic processor is also configured to track a passage of time, an activity level, or both. If the passage of time is greater than or equal to the threshold time, the activity level is greater than or equal to the threshold activity level, or both then the electronic processor is configured to output a user notification, via the output device.Type: GrantFiled: January 8, 2018Date of Patent: March 19, 2019Assignee: METREX RESEARCH, LLCInventors: Steven Burns, Abhigyan Som, Tuyen Quang Nguyen
-
Patent number: 10143753Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: GrantFiled: August 22, 2017Date of Patent: December 4, 2018Assignee: University of MassachusettsInventors: Gregory N. Tew, Gregory J. Gabriel, Abhigyan Som, Arife Ozgul Tezgel
-
Publication number: 20180044615Abstract: Stabilized hydrogen peroxide-containing compositions and methods of making same are disclosed. The compositions contain a stabilizer system made up of a disulfonate surfactant, a diester solvent, and a sulfonic acid or a salt thereof in a sufficient quantity to provide the stabilized hydrogen peroxide with an acidic pH value. The compositions are suitable for use as disinfectants, as cleaning agents, and in various personal care applications such as hair care and tooth whitening.Type: ApplicationFiled: August 31, 2017Publication date: February 15, 2018Inventors: Abhigyan Som, Harish Jani
-
Publication number: 20180043025Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: ApplicationFiled: August 22, 2017Publication date: February 15, 2018Inventors: Gregory N. Tew, Gregory J. Gabriel, Abhigyan Som, Arife Ozgul Tezgel
-
Publication number: 20170340413Abstract: A method for continuously evaluating the effectiveness of debridement of a root canal of a tooth, the tooth having an open access cavity and an apex end, includes delivering a fluid to the open access cavity of the tooth, evacuating the fluid near the apex end of the tooth such that the fluid flushes most of the root canal before being evacuated, and continuously evaluating the evacuated fluid for at least one of a presence of debris, a concentration level of the debris, or a type of the debris. An apparatus for use in debriding a root canal of a tooth includes a microcannula or a macrocannula configured to evacuate a fluid in the root canal, and a sensing mechanism fluidically coupled to the microcannula or the macrocannula, the sensing mechanism configured to continuously sense debris in the evacuated fluid in real time.Type: ApplicationFiled: May 25, 2017Publication date: November 30, 2017Inventors: Steven Joseph Burns, Emanuele Maretto, Abhigyan Som, Carlos Alberto Munoz, Matteo Bosisio, Gopikrishnan Soundararajan, Tuyen Nguyen, M. Reza Mehrabi
-
Patent number: 9770511Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: GrantFiled: June 7, 2016Date of Patent: September 26, 2017Assignee: University of MassachusettsInventors: Gregory N. Tew, Gregory J. Gabriel, Abhigyan Som, Arife Ozgul Tezgel
-
Patent number: 9765287Abstract: Stabilized hydrogen peroxide-containing compositions and methods of making same are disclosed. The compositions contain a stabilizer system made up of a disulfonate surfactant, a diester solvent, and a sulfonic acid or a salt thereof in a sufficient quantity to provide the stabilized hydrogen peroxide with an acidic pH value. The compositions are suitable for use as disinfectants, as cleaning agents, and in various personal care applications such as hair care and tooth whitening.Type: GrantFiled: June 3, 2015Date of Patent: September 19, 2017Assignee: Metrex Research CorporationInventors: Abhigyan Som, Harish Jani
-
Publication number: 20170208812Abstract: A disinfectant includes a source of chlorine, a buffer system, a pH adjuster, and a polar carrier. The disinfectant has a pH of 9.9-11 and activity against Clostridium difficile spores and Mycobacterium within a 3 minute kill time. In one embodiment, the disinfectant includes sodium hypochlorite as a source of chlorine, a carbonate or phosphate buffer system, a hydroxide pH adjuster, and a polar carrier, wherein the disinfectant has a pH of 10.0-10.5 and kills at least 90% of Clostridium difficile spores and Mycobacterium within a 3 minute kill time.Type: ApplicationFiled: January 25, 2017Publication date: July 27, 2017Inventors: Abhigyan Som, Olga Borokhov, Timothy J. Taylor, Harish Jani, Anabell Jackson, Robert Carrier
-
Publication number: 20160355760Abstract: Stabilized hydrogen peroxide-containing compositions and methods of making same are disclosed. The compositions contain a stabilizer system made up of a disulfonate surfactant, a diester solvent, and a sulfonic acid or a salt thereof in a sufficient quantity to provide the stabilized hydrogen peroxide with an acidic pH value. The compositions are suitable for use as disinfectants, as cleaning agents, and in various personal care applications such as hair care and tooth whitening.Type: ApplicationFiled: June 3, 2015Publication date: December 8, 2016Inventors: Abhigyan Som, Harish Jani
-
Publication number: 20160324970Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: ApplicationFiled: June 7, 2016Publication date: November 10, 2016Inventors: Gregory N. Tew, Gregory J Gabriel, Abhigyan Som, Arife Ozgul Tezgel
-
Patent number: 9382366Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: GrantFiled: June 24, 2011Date of Patent: July 5, 2016Assignee: University of MassachusettsInventors: Gregory N. Tew, Gregory J. Gabriel, Abhigyan Som, Arife Ozgul Tezgel
-
Patent number: 9170205Abstract: An indicator kit for detecting the presence of a quaternary ammonium compound disinfectant is provided. The kit includes an indicator composition that includes an azo dye material and water; an extraction composition that includes water, and at least one of a C1-C7 alcohol or a glycol ether; and an acidic compound present in at least one of the indicator composition, the extraction composition, or an acidic developer solution packaged separately from the indicator composition and the extraction composition. A method of detecting a quaternary ammonium compound disinfectant on a surface is also provided.Type: GrantFiled: September 18, 2013Date of Patent: October 27, 2015Assignee: Metrex Research, LLCInventors: Steven Joseph Burns, Abhigyan Som, Walter Joseph Tulpinski
-
Publication number: 20150079690Abstract: An indicator kit for detecting the presence of a quaternary ammonium compound disinfectant is provided. The kit includes an indicator composition that includes an azo dye material and water; an extraction composition that includes water, and at least one of a C1-C7 alcohol or a glycol ether; and an acidic compound present in at least one of the indicator composition, the extraction composition, or an acidic developer solution packaged separately from the indicator composition and the extraction composition. A method of detecting a quaternary ammonium compound disinfectant on a surface is also provided.Type: ApplicationFiled: September 18, 2013Publication date: March 19, 2015Applicant: Metrex Research, LLCInventors: Steven Joseph Burns, Abhigyan Som, Walter Joseph Tulpinski
-
Publication number: 20130280237Abstract: The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.Type: ApplicationFiled: June 24, 2011Publication date: October 24, 2013Applicant: University of MassachusettsInventors: Gregory N. Tew, Gregory J. Gabriel, Abhigyan Som, Arife Ozgul Tezgel